{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T16:09:53Z","timestamp":1787587793247,"version":"build-2736575974"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T00:00:00Z","timestamp":1707264000000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["T2225017"],"award-info":[{"award-number":["T2225017"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52\u2009073\u2009138"],"award-info":[{"award-number":["52\u2009073\u2009138"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Science Technology and Innovation Committee of Shenzhen Municipality","award":["JCYJ20210324120202007"],"award-info":[{"award-number":["JCYJ20210324120202007"]}]},{"name":"Shenzhen Sci-Tech Fund","award":["YTDPT20181011104007"],"award-info":[{"award-number":["YTDPT20181011104007"]}]},{"name":"Guangdong Provincial Key Laboratory Program","award":["2021B1212040001"],"award-info":[{"award-number":["2021B1212040001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>High intraocular pressure (IOP) is one of the high-risk pathogenic factors of glaucoma. Existing methods of IOP measurement are based on the direct interaction with the cornea. Commercial ophthalmic tonometers based on snapshot measurements are expensive, bulky, and their operation requires trained personnel. Theranostic contact lenses are easy to use, but they may block vision and cause infection. Here, we report a sensory system for IOP assessment that uses a soft indentor with two asymmetrically deployed iontronic flexible pressure sensors to interact with the eyelid-eyeball in an eye-closed situation. Inspired by human fingertip assessment of softness, the sensory system extracts displacement-pressure information for soft evaluation, achieving high accuracy IOP monitoring (&amp;gt;96%). We further design and custom-make a portable and wearable ophthalmic tonometer based on the sensory system and demonstrate its high efficacy in IOP screening. This sensory system paves a way towards cost-effective, robust, and reliable IOP monitoring.<\/jats:p>","DOI":"10.1093\/nsr\/nwae050","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T09:58:45Z","timestamp":1707299925000},"source":"Crossref","is-referenced-by-count":23,"title":["Displacement-pressure biparametrically regulated softness sensory system for intraocular pressure monitoring"],"prefix":"10.1093","volume":"11","author":[{"given":"Yu","family":"Cheng","sequence":"first","affiliation":[{"name":"Department of Materials Science and Engineering, Southern University of Science and Technology , Shenzhen 518055 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifei","family":"Zhan","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering, Southern University of Science and Technology , Shenzhen 518055 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangyi","family":"Guan","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering, Southern University of Science and Technology , Shenzhen 518055 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junli","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering, Southern University of Science and Technology , Shenzhen 518055 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingxiao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering, Southern University of Science and Technology , Shenzhen 518055 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering, Southern University of Science and Technology , Shenzhen 518055 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Zubair","sequence":"additional","affiliation":[{"name":"Department of Engineering Science and Mechanics, Pennsylvania State University , State College 16802 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cunjiang","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Engineering Science and Mechanics, Pennsylvania State University , State College 16802 , USA"},{"name":"Department of Biomedical Engineering, Pennsylvania State University , State College 16802 , USA"},{"name":"Department of Materials Science and Engineering, Materials Research Institute, Pennsylvania State University , State College 16802 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4513-3117","authenticated-orcid":false,"given":"Chuan Fei","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering, Southern University of Science and Technology , Shenzhen 518055 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,2,6]]},"reference":[{"key":"2024050314423232300_bib1","doi-asserted-by":"publisher","first-page":"501","DOI":"10.2165\/11533180-000000000-00000","article-title":"Ocular adverse effects of common psychotropic agents","volume":"24","author":"Richa","year":"2010","journal-title":"CNS Drugs"},{"key":"2024050314423232300_bib2","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1136\/bjo.2005.081224","article-title":"The number of people with glaucoma worldwide in 2010 and 2020","volume":"90","author":"Quigley","year":"2006","journal-title":"Br J 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