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Concurrently, several nutritional therapies and alternative supportive treatments are also being used and tested to reduce the mortality associated with acute respiratory distress in patients with COVID-19. In the context of COVID-19, improved nutrition that includes micronutrient supplementation to augment the immune system has been recognized as a viable approach to both prevent and alleviate the severity of the infection. The potential role of micronutrients as immune-boosting agents is particularly relevant for low- and middle-income countries, which already have an existing high burden of undernutrition and micronutrient deficiencies. A systematic literature review was performed to identify nutritional interventions that might prevent or aid in the recovery from COVID-19. The PubMed, ScienceDirect, Cochrane, Scopus, Web of Science, and Google Scholar databases were searched electronically from February to April 2020. All abstracts and full-text articles were examined for their relevance to this review. The information gathered was collated under various categories. Deficiencies of micronutrients, especially vitamins\u2009A, B complex, C, and D, zinc, iron, and selenium, are common among vulnerable populations in general and among COVID-19 patients in particular and could plausibly increase the risk of mortality. Judicious use of need-based micronutrient supplementation, alongside existing micronutrient fortification programs, is warranted in the current global pandemic, especially in low- and middle-income economies.<\/jats:p>","DOI":"10.1093\/nutrit\/nuaa063","type":"journal-article","created":{"date-parts":[[2020,6,4]],"date-time":"2020-06-04T15:12:24Z","timestamp":1591283544000},"page":"289-300","source":"Crossref","is-referenced-by-count":76,"title":["Nutritional perspectives for the prevention and mitigation of COVID-19"],"prefix":"10.1093","volume":"79","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7806-1212","authenticated-orcid":false,"given":"Saeed","family":"Akhtar","sequence":"first","affiliation":[{"name":"Institute of Food Science and Nutrition, Bahauddin Zakariya University, Multan, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jai K","family":"Das","sequence":"additional","affiliation":[{"name":"Centre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tariq","family":"Ismail","sequence":"additional","affiliation":[{"name":"Institute of Food Science and Nutrition, Bahauddin Zakariya University, Multan, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muqeet","family":"Wahid","sequence":"additional","affiliation":[{"name":"Division of Woman and Child Health, Aga Khan University Hospital, Karachi, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wisha","family":"Saeed","sequence":"additional","affiliation":[{"name":"Institute of Food Science and Nutrition, Bahauddin Zakariya University, Multan, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zulfiqar A","family":"Bhutta","sequence":"additional","affiliation":[{"name":"Centre of Excellence in Women and Child Health, Aga Khan University, Karachi, 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