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Over the years, clinical studies have accumulated evidence that viral or bacterial infections may promote the onset of eating disorders such as AN. This review aims to describe how infections and the subsequent immune responses affect food intake regulation in the short term and also how these processes may lead to long-term intestinal disorders, including gut barrier disruption and gut microbiota dysbiosis, even after the clearance of the pathogens. We discuss in particular how infection-mediated intestinal dysbiosis may promote the onset of several AN symptoms and comorbidities, including appetite dysregulation, functional gastrointestinal disorders, and mood disorders.<\/jats:p>","DOI":"10.1093\/nutrit\/nuab030","type":"journal-article","created":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T12:34:33Z","timestamp":1616502873000},"page":"381-391","source":"Crossref","is-referenced-by-count":18,"title":["Role of microbiota-gut-brain axis dysfunctions induced by infections in the onset of anorexia nervosa"],"prefix":"10.1093","volume":"80","author":[{"given":"Marie","family":"Galmiche","sequence":"first","affiliation":[{"name":"Nutrition Department, CHU Rouen, F-76000 Rouen, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Najate","family":"Achamrah","sequence":"additional","affiliation":[{"name":"Nutrition Department, CHU Rouen, F-76000 Rouen, France"},{"name":"UNIROUEN, INSERM UMR 1073, Nutrition, Gut and Brain Laboratory, Rouen, France"},{"name":"UNIROUEN, Institute for Research and Innovation in Biomedicine, Normandie University, Rouen, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"D\u00e9chelotte","sequence":"additional","affiliation":[{"name":"Nutrition Department, CHU Rouen, F-76000 Rouen, France"},{"name":"UNIROUEN, Institute for Research and Innovation in Biomedicine, Normandie University, Rouen, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Ribet","sequence":"additional","affiliation":[{"name":"UNIROUEN, INSERM UMR 1073, Nutrition, Gut and Brain Laboratory, Rouen, France"},{"name":"UNIROUEN, Institute for Research and Innovation in Biomedicine, Normandie University, Rouen, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Breton","sequence":"additional","affiliation":[{"name":"Nutrition Department, CHU Rouen, F-76000 Rouen, France"},{"name":"UNIROUEN, INSERM UMR 1073, Nutrition, Gut and Brain Laboratory, Rouen, France"},{"name":"UNIROUEN, Institute for Research and Innovation in Biomedicine, Normandie University, Rouen, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,5,19]]},"reference":[{"key":"2022021009333541400_nuab030-B1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders: DSM-5","year":"2013"},{"key":"2022021009333541400_nuab030-B2","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1002\/eat.23243","article-title":"Association between gastrointestinal complaints and psychopathology in patients with anorexia nervosa","volume":"53","author":"Kessler","year":"2020","journal-title":"Int J Eat Disord."},{"key":"2022021009333541400_nuab030-B3","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1002\/eat.22462","article-title":"Gastrointestinal complications associated with anorexia nervosa: a systematic 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The case for enhanced apoptosis of infected cells","volume":"54","author":"LeGrand","year":"2000","journal-title":"Med Hypotheses."},{"key":"2022021009333541400_nuab030-B91","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.amjmed.2015.06.031","article-title":"Medical complications of anorexia nervosa and bulimia","volume":"129","author":"Westmoreland","year":"2016","journal-title":"Am J Med."},{"key":"2022021009333541400_nuab030-B92","doi-asserted-by":"crossref","first-page":"21887","DOI":"10.1038\/srep21887","article-title":"Maintaining physical activity during refeeding improves body composition, intestinal hyperpermeability and behavior in anorectic mice","volume":"6","author":"Achamrah","year":"2016","journal-title":"Sci Rep."},{"key":"2022021009333541400_nuab030-B93","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1159\/000479918","article-title":"Bacterial translocation from the gut to the distant organs: an 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One."},{"key":"2022021009333541400_nuab030-B102","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1038\/nature09415","article-title":"Gut inflammation provides a respiratory electron acceptor for Salmonella","volume":"467","author":"Winter","year":"2010","journal-title":"Nature"},{"key":"2022021009333541400_nuab030-B103","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1126\/science.1232467","article-title":"Host-derived nitrate boosts growth of E. coli in the inflamed gut","volume":"339","author":"Winter","year":"2013","journal-title":"Science."},{"key":"2022021009333541400_nuab030-B104","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.tim.2016.12.008","article-title":"The role of reactive oxygen species in antibiotic-mediated killing of bacteria","volume":"25","author":"Van Acker","year":"2017","journal-title":"Trends Microbiol."},{"key":"2022021009333541400_nuab030-B105","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.imlet.2014.04.014","article-title":"The impact of intestinal inflammation on the nutritional environment of the gut microbiota","volume":"162","author":"Faber","year":"2014","journal-title":"Immunol Lett."},{"key":"2022021009333541400_nuab030-B106","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1038\/ismej.2013.80","article-title":"Dysbiosis in inflammatory bowel diseases: the oxygen hypothesis","volume":"7","author":"Rigottier-Gois","year":"2013","journal-title":"Isme J."},{"key":"2022021009333541400_nuab030-B107","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S1473-3099(01)00066-4","article-title":"Effect of antimicrobial agents on the ecological balance of human microflora","volume":"1","author":"Sullivan","year":"2001","journal-title":"Lancet Infect Dis."},{"key":"2022021009333541400_nuab030-B108","doi-asserted-by":"crossref","first-page":"E0220642","DOI":"10.1371\/journal.pone.0220642","article-title":"The long-term consequences of antibiotic therapy: role of colonic short-chain fatty acids (SCFA) system and intestinal barrier integrity","volume":"14","author":"Holota","year":"2019","journal-title":"PLoS One."},{"key":"2022021009333541400_nuab030-B109","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.yclnex.2019.05.001","article-title":"Intestinal microbiota and anorexia nervosa","volume":"28","author":"Breton","year":"2019","journal-title":"Clin Nutr Exp"},{"key":"2022021009333541400_nuab030-B110","doi-asserted-by":"crossref","first-page":"E65465","DOI":"10.1371\/journal.pone.0065465","article-title":"Gut microbiota composition in male rat models under different nutritional status and physical activity and its association with serum leptin and ghrelin 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Escherichia coli","volume":"37","author":"Million","year":"2013","journal-title":"Int J Obes"},{"key":"2022021009333541400_nuab030-B114","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.bbi.2015.03.016","article-title":"Altered fecal microbiota composition in patients with major depressive disorder","volume":"48","author":"Jiang","year":"2015","journal-title":"Brain Behav Immun."},{"key":"2022021009333541400_nuab030-B115","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.jpsychires.2018.07.007","article-title":"Altered gut microbiota profile in patients with generalized anxiety disorder","volume":"104","author":"Jiang","year":"2018","journal-title":"J Psychiatr Res."},{"key":"2022021009333541400_nuab030-B116","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.3389\/fimmu.2019.01551","article-title":"The commensal microbiota and viral infection: a comprehensive review","volume":"10","author":"Li","year":"2019","journal-title":"Front Immunol"},{"key":"2022021009333541400_nuab030-B117","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1093\/cid\/ciy205","article-title":"Gut dysbiosis associated with hepatitis C virus infection","volume":"67","author":"Inoue","year":"2018","journal-title":"Clin Infect Dis."},{"key":"2022021009333541400_nuab030-B118","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.clnu.2020.05.002","article-title":"Gut microbiota alteration in a mouse model of anorexia nervosa","volume":"40","author":"Breton","year":"2021","journal-title":"Clin Nutr."},{"key":"2022021009333541400_nuab030-B119","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.3389\/fmicb.2017.02222","article-title":"Gut microbial dysbiosis is associated with altered hepatic functions and serum metabolites in chronic hepatitis B patients","volume":"8","author":"Wang","year":"2017","journal-title":"Front Microbiol"},{"key":"2022021009333541400_nuab030-B120","doi-asserted-by":"crossref","first-page":"2304","DOI":"10.1016\/j.clnu.2018.10.004","article-title":"Altered host-gut microbes symbiosis in severely malnourished anorexia nervosa (AN) patients undergoing enteral nutrition: an explicative factor of functional intestinal disorders?","volume":"38","author":"Hanachi","year":"2019","journal-title":"Clin Nutr."},{"key":"2022021009333541400_nuab030-B121","doi-asserted-by":"crossref","first-page":"E0173124","DOI":"10.1371\/journal.pone.0173124","article-title":"Human norovirus binding to select bacteria representative of the human gut microbiota","volume":"12","author":"Almand","year":"2017","journal-title":"PLoS One."},{"key":"2022021009333541400_nuab030-B122","doi-asserted-by":"crossref","first-page":"44377","DOI":"10.1038\/srep44377","article-title":"Gut dysbiosis and neuroimmune responses to brain infection with Theiler\u2019s murine encephalomyelitis virus","volume":"7","author":"Carrillo-Salinas","year":"2017","journal-title":"Sci Rep."},{"key":"2022021009333541400_nuab030-B123","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1210\/en.2019-00408","article-title":"The gut microbiome derived from anorexia nervosa patients impairs weight gain and behavioral performance in female mice","volume":"160","author":"Hata","year":"2019","journal-title":"Endocrinology"},{"key":"2022021009333541400_nuab030-B124","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1097\/PSY.0000000000000247","article-title":"The intestinal microbiota in acute anorexia nervosa and during renourishment: relationship to depression, anxiety, and eating disorder psychopathology","volume":"77","author":"Kleiman","year":"2015","journal-title":"Psychosom Med."},{"key":"2022021009333541400_nuab030-B125","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1574-6941.1996.tb00212.x","article-title":"Acetogenesis from H2 and CO2 by methane-and non-methane-producing human colonic bacterial communities","volume":"19","author":"Bernalier","year":"1996","journal-title":"FEMS Microbiol Ecol"},{"key":"2022021009333541400_nuab030-B126","doi-asserted-by":"crossref","first-page":"E7125","DOI":"10.1371\/journal.pone.0007125","article-title":"Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and methanogens in anorexic patients","volume":"4","author":"Armougom","year":"2009","journal-title":"PloS One"},{"key":"2022021009333541400_nuab030-B127","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/j.nut.2008.06.021","article-title":"Emerging role of autoantibodies against appetite-regulating neuropeptides in eating disorders","volume":"24","author":"Fetissov","year":"2008","journal-title":"Nutrition."},{"key":"2022021009333541400_nuab030-B128","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2014.98","article-title":"Bacterial ClpB heat-shock protein, an antigen-mimetic of the anorexigenic peptide \u03b1-MSH, at the origin of eating disorders","volume":"4","author":"Tennoune","year":"2014","journal-title":"Transl Psychiatry."},{"key":"2022021009333541400_nuab030-B129","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.cmet.2015.10.017","article-title":"Gut commensal E. coli proteins activate host satiety pathways following nutrient-induced bacterial growth","volume":"23","author":"Breton","year":"2016","journal-title":"Cell Metab."},{"key":"2022021009333541400_nuab030-B130","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1002\/eat.22531","article-title":"Elevated plasma concentrations of bacterial ClpB protein in patients with eating disorders","volume":"49","author":"Breton","year":"2016","journal-title":"Int J Eat Disord."},{"key":"2022021009333541400_nuab030-B131","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.3390\/nu11092115","article-title":"Effects of macronutrients on the in vitro production 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intestine","volume":"7","author":"Cao","year":"2017","journal-title":"Sci Rep."},{"key":"2022021009333541400_nuab030-B139","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1053\/j.gastro.2016.09.049","article-title":"Identification of an intestinal microbiota signature associated with severity of irritable bowel syndrome","volume":"152","author":"Tap","year":"2017","journal-title":"Gastroenterology"},{"key":"2022021009333541400_nuab030-B140","doi-asserted-by":"crossref","first-page":"Eaaf6397","DOI":"10.1126\/scitranslmed.aaf6397","article-title":"Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice","volume":"9","author":"De","year":"2017","journal-title":"Sci Translat Med"},{"key":"2022021009333541400_nuab030-B141","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.jpsychores.2004.04.375","article-title":"Eating disorders and irritable bowel syndrome: is there a 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