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These disorders are grouped under the term fetal alcohol spectrum disorders (FASDs). Adequate nutrition and a conducive intrauterine environment are essential for healthy fetal development. Nutrient deficiencies resulting from inadequate maternal nutrient ingestion may be compounded by alcohol-induced altered nutrient metabolism, placental clearance, and malabsorption. Alcohol-induced alteration of the intrauterine environment is the main source of developmental deficits and nutritional insufficiencies can worsen the effects on fetal development. In this review, we discuss studies examining the collective and interactive effects of nutrition (specifically iron, selenium, vitamin\u2009A, thiamine, zinc, folate, vitamin B12, choline, and amino acids) relative to gestational alcohol consumption and its effects on fetal growth and development. We also summarize scientific reports that tested potential benefits of micronutrient supplementation in animal models of fetal alcohol spectrum disorders and in humans. In summary, the deleterious effects of alcohol exposure in relation to nutrient homeostasis further validate that avoidance of alcohol consumption during pregnancy is the most effective way to mitigate the teratogenic effects of alcohol.<\/jats:p>","DOI":"10.1093\/nutrit\/nuab119","type":"journal-article","created":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T12:50:15Z","timestamp":1639054215000},"page":"1568-1579","source":"Crossref","is-referenced-by-count":37,"title":["Effects of nutrition and gestational alcohol consumption on fetal growth and development"],"prefix":"10.1093","volume":"80","author":[{"given":"Vishal D","family":"Naik","sequence":"first","affiliation":[{"name":"Department of Obstetrics & Gynecology, C.S. Mott Center for Human Growth and Development, School of Medicine, Wayne State University, Detroit, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jehoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoyao","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Texas A&M University, College Station, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon","family":"Washburn","sequence":"additional","affiliation":[{"name":"Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9778-5224","authenticated-orcid":false,"given":"Jayanth","family":"Ramadoss","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, C.S. Mott Center for Human Growth and Development, School of Medicine, Wayne State University, Detroit, Michigan, USA"},{"name":"Department of Physiology, School of Medicine, Wayne State University, Detroit, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,5,4]]},"reference":[{"key":"2022051008251863000_nuab119-B1","doi-asserted-by":"crossref","first-page":"2996","DOI":"10.1001\/jama.290.22.2996","article-title":"Fetal alcohol spectrum disorder","volume":"290","author":"Sokol","year":"2003","journal-title":"JAMA"},{"key":"2022051008251863000_nuab119-B2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/tera.1420120102","article-title":"The fetal alcohol 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