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Major dietary sources of salicylates were found in spices and herbs, such as curry and paprika (hot powder). Several studies suggest that these natural salicylates offer health benefits in the human body, such as antidiabetic, anticancer, antiviral, and anti-inflammatory properties. However, despite their advantages, salicylates can be harmful to people with allergies, and high doses of salicylates may cause respiratory alkalosis and gastrointestinal bleeding. Additionally, salicylates can interact with certain drugs, such as nonsteroidal anti-inflammatory drugs and warfarin. This narrative review aimed to consolidate recent information on the content of salicylates in food based on the literature, while also highlighting the benefits and risks associated with salicylate consumption in humans. Based on the literature review and analysis of results, it can be concluded that the dietary intake of salicylates in vegetarians can be relatively high, resulting in concentrations of salicylic acid in the blood and urine that are comparable to those observed in patients taking a low dose of aspirin (75\u2009mg). This suggests that a diet rich in salicylates may have potential benefits in preventing and treating some diseases that require low doses of aspirin.<\/jats:p>","DOI":"10.1093\/nutrit\/nuad136","type":"journal-article","created":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T05:45:51Z","timestamp":1698471951000},"page":"1594-1604","source":"Crossref","is-referenced-by-count":14,"title":["Risks and benefits of salicylates in food: a narrative review"],"prefix":"10.1093","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0937-8427","authenticated-orcid":false,"given":"Joanna","family":"Suliburska","sequence":"first","affiliation":[{"name":"Department of Human Nutrition and Dietetics, Faculty of Food Science and Nutrition, Poznan University of Life Sciences , Pozna\u0144,","place":["Poland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafsan Syabani","family":"Cholik","sequence":"additional","affiliation":[{"name":"Department of Human Nutrition and Dietetics, Faculty of Food Science and Nutrition, Poznan University of Life Sciences , Pozna\u0144,","place":["Poland"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,10,27]]},"reference":[{"key":"2024101007511870200_nuad136-B1","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1146\/annurev.phyto.050908.135202","article-title":"Salicylic acid, a multifaceted hormone to combat disease","volume":"47","author":"Vlot","year":"2009","journal-title":"Annu Rev Phytopathol."},{"key":"2024101007511870200_nuad136-B2","doi-asserted-by":"publisher","first-page":"206","DOI":"10.3389\/fimmu.2016.00206","article-title":"Multiple targets of salicylic acid and its derivatives in plants and animals","volume":"7","author":"Klessig","year":"2016","journal-title":"Front Immunol"},{"key":"2024101007511870200_nuad136-B3","doi-asserted-by":"publisher","first-page":"839","DOI":"10.3390\/foods10040839","article-title":"Potential health benefits of plant food-derived bioactive components: an overview","volume":"10","author":"Samtiya","year":"2021","journal-title":"Foods"},{"key":"2024101007511870200_nuad136-B4","doi-asserted-by":"publisher","first-page":"1753","DOI":"10.3390\/ijms20071753","article-title":"Salicylate and procyanidin-rich stem extracts of Gaultheria procumbens L. inhibit pro-inflammatory enzymes and suppress pro-inflammatory and pro-oxidant functions of human neutrophils ex-vivo","volume":"20","author":"Michel","year":"2019","journal-title":"Int J Mol Sci"},{"key":"2024101007511870200_nuad136-B5","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1039\/c1fo10128e","article-title":"Natural salicylates: foods, functions and disease prevention","volume":"2","author":"Duthie","year":"2011","journal-title":"Food Funct"},{"key":"2024101007511870200_nuad136-B6","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1111\/j.1744-7348.2002.tb00176.x","article-title":"Can aspirin help identify leaf proteins active in defence responses?","volume":"140","author":"Pierpoint","year":"2002","journal-title":"Ann Appl Biol."},{"key":"2024101007511870200_nuad136-B7","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1016\/s0002-8223(21)03743-3v","article-title":"Salicylates in foods","volume":"85","author":"Swain","year":"1985","journal-title":"J Am Diet Assoc"},{"key":"2024101007511870200_nuad136-B8","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1016\/j.ijcard.2012.09.192","article-title":"Mediterranean diet: natural salicylates and other secrets of the pyramid","volume":"166","author":"Siniorakis","year":"2013","journal-title":"Int J Cardiol."},{"key":"2024101007511870200_nuad136-B9","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1016\/b0-12-369400-0\/00861-9","volume-title":"Encyclopedia of Toxicology","author":"Baer","year":"2005"},{"key":"2024101007511870200_nuad136-B10","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1136\/jcp.56.9.651","article-title":"Urinary excretion of salicyluric and salicylic acids by non-vegetarians, vegetarians, and patients taking low dose aspirin","volume":"56","author":"Lawrence","year":"2003","journal-title":"J Clin Pathol."},{"key":"2024101007511870200_nuad136-B11","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1136\/jcp.54.7.553","article-title":"Salicylic acid in the serum of subjects not taking aspirin. 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