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According to the Rome IV criteria, irritable bowel syndrome and functional dyspepsia are the most common FGIDs. Complementary and alternative medicines are employed by increasing numbers of individuals around the world, and they include herbal and dietary supplements, acupuncture, and hypnosis. Of these, herbal and dietary supplements seem to have the greatest potential for relieving FGIDs, through multiple modes of action. However, despite the extensive application of natural extracts in alternative treatments for FGIDs, the safety and effectiveness of food and orally ingested food-derived extracts remain uncertain. Many randomized controlled trials have provided compelling evidence supporting their potential, as detailed in this review. The consumption of certain foods (eg, kiwifruit, mentha, ginger, etc) and food ingredients may contribute to the alleviation of symptoms associated with FGID,. However, it is crucial to emphasize that the short-term consumption of these components may not yield satisfactory efficacy. Physicians are advised to share both the benefits and potential risks of these alternative therapies with patients. Furthermore, larger randomized clinical trials with appropriate comparators are imperative.<\/jats:p>","DOI":"10.1093\/nutrit\/nuae047","type":"journal-article","created":{"date-parts":[[2024,6,22]],"date-time":"2024-06-22T16:51:20Z","timestamp":1719075080000},"page":"e1158-e1171","source":"Crossref","is-referenced-by-count":9,"title":["The effectiveness and safety of natural food and food-derived extract supplements for treating functional gastrointestinal disorders\u2014current perspectives"],"prefix":"10.1093","volume":"83","author":[{"given":"Tianxu","family":"Liu","sequence":"first","affiliation":[{"name":"College of Food Science and Technology, Huazhong Agricultural University , Wuhan, Hubei 430070,","place":["China"]},{"name":"Key Laboratory of Environment Correlative Dietology (Huazhong Agricultural University), Ministry of Education , Wuhan, Hubei 430070,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismail Muhammad","family":"Asif","sequence":"additional","affiliation":[{"name":"College of Food Science and Technology, Huazhong Agricultural University , Wuhan, Hubei 430070,","place":["China"]},{"name":"Key Laboratory of Environment Correlative Dietology (Huazhong Agricultural University), Ministry of Education , Wuhan, Hubei 430070,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengmei","family":"Bai","sequence":"additional","affiliation":[{"name":"College of Food Science and Technology, Huazhong Agricultural University , Wuhan, Hubei 430070,","place":["China"]},{"name":"Key Laboratory of Environment Correlative Dietology (Huazhong Agricultural University), Ministry of Education , Wuhan, Hubei 430070,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutian","family":"Huang","sequence":"additional","affiliation":[{"name":"College of Food Science and Technology, Huazhong Agricultural University , Wuhan, Hubei 430070,","place":["China"]},{"name":"Key Laboratory of Environment Correlative Dietology (Huazhong Agricultural University), Ministry of Education , Wuhan, Hubei 430070,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Li","sequence":"additional","affiliation":[{"name":"College of Food Science and Technology, Huazhong Agricultural University , Wuhan, Hubei 430070,","place":["China"]},{"name":"Key Laboratory of Environment Correlative Dietology (Huazhong Agricultural University), Ministry of Education , Wuhan, Hubei 430070,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1076-0500","authenticated-orcid":false,"given":"Ling","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Food Science and Technology, Huazhong Agricultural University , Wuhan, Hubei 430070,","place":["China"]},{"name":"Key Laboratory of Environment Correlative Dietology (Huazhong 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