{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T14:02:53Z","timestamp":1791640973411,"version":"4.3.4"},"reference-count":81,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"publisher","award":["401761\/2022\u20133"],"award-info":[{"award-number":["401761\/2022\u20133"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Context<\/jats:title>\n                    <jats:p>Although it is well established that caloric restriction (CR) is the primary driver of weight loss, circadian-driven metabolic benefits have been recognized as possibly enhancing the effects of CR. Time-restricted eating (TRE) has emerged as a promising approach in this context.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We conducted a systematic review and meta-analysis to compare the effects of TRE with isocaloric diet controls (analysis 1) and non-isocaloric controls (analysis 2) on anthropometric and body-composition parameters in adults with overweight or obesity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>A search was carried out in the Medline, LILACS, Embase, and CENTRAL databases using Medical Subject Heading (MeSH) and similar terms such as \u201cObesity,\u201d \u201cObesity, Abdominal,\u201d \u201cTime-restricted eating,\u201d \u201cBody weight,\u201d \u201cChanges in body weight,\u201d and others.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Extraction<\/jats:title>\n                    <jats:p>We included 30 studies involving a total of 1341 participants. Studies were screened based on titles and abstracts followed by full-text reading, and data were extracted from eligible studies using a pre-established form. All these steps were performed by 2 authors independently and blinded, with discrepancies resolved by a third author.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Analysis<\/jats:title>\n                    <jats:p>The results of main findings revealed that, in studies using non-isocaloric controls, the TRE group showed significant reductions in body weight (BW) (mean difference [MD]: \u20132.82\u2009kg; 95% CI: \u20133.49, \u20132.15), fat mass (FM) (MD: \u20131.36\u2009kg; 95% CI: \u20132.09, \u20130.63), and fat-free mass (FFM) (MD: \u20130.86\u2009kg; 95% CI: \u20131.23, \u20130.49). In studies that used isocaloric control strategies, the TRE group showed significant reductions in BW (MD: \u20131.46\u2009kg; 95% CI: \u20132.65, \u20130.26), FM (MD: \u20131.50\u2009kg; 95% CI: \u20132.77, \u20130.24), and FFM (MD: \u20130.41\u2009kg; 95% CI: \u20130.79, \u20130. 03).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>TRE yields favorable anthropometric and clinical outcomes, even when intake is isocaloric between the intervention and control groups. This result suggests that circadian effects may enhance the impact of CR on excess weight.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Systematic Review Registration<\/jats:title>\n                    <jats:p>PROSPERO registration no. CRD42022301594.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/nutrit\/nuaf053","type":"journal-article","created":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T16:30:05Z","timestamp":1743438605000},"page":"463-486","source":"Crossref","is-referenced-by-count":8,"title":["Systematic Review and Meta-analysis of Randomized Clinical Trials Comparing Time-Restricted Eating With and Without Caloric Restriction for Weight Loss"],"prefix":"10.1093","volume":"84","author":[{"given":"Danielle","family":"Fernandes-Alves","sequence":"first","affiliation":[{"name":"Chrononutrition Research Group (Cronutri), School of Medicine, Federal University of Uberlandia , Uberl\u00e2ndia, Minas Gerais 38405-320,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1568-4137","authenticated-orcid":false,"given":"Gabriela Pereira","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Chrononutrition Research Group (Cronutri), School of Medicine, Federal University of Uberlandia , Uberl\u00e2ndia, Minas Gerais 38405-320,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5500-2981","authenticated-orcid":false,"given":"Kisian Costa","family":"Guimar\u00e3es","sequence":"additional","affiliation":[{"name":"Chrononutrition Research Group (Cronutri), School of Medicine, Federal University of Uberlandia , Uberl\u00e2ndia, Minas Gerais 38405-320,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cibele A","family":"Crispim","sequence":"additional","affiliation":[{"name":"Chrononutrition Research Group (Cronutri), School of Medicine, Federal University of Uberlandia , Uberl\u00e2ndia, Minas Gerais 38405-320,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,4,29]]},"reference":[{"key":"2026021210022314000_nuaf053-B1","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1038\/s41574-019-0176-8","article-title":"Obesity: global epidemiology and pathogenesis","volume":"15","author":"Bl\u00fcher","year":"2019","journal-title":"Nat Rev Endocrinol"},{"key":"2026021210022314000_nuaf053-B2","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1056\/NEJMoa1614362","article-title":"Health effects of overweight and obesity in 195 countries over 25 years","volume":"377","author":"Afshin","year":"2017","journal-title":"N Engl J Med"},{"key":"2026021210022314000_nuaf053-B3","doi-asserted-by":"publisher","first-page":"1947","DOI":"10.1016\/S0140-6736(16)00271-3","article-title":"Management of obesity","volume":"387","author":"Bray","year":"2016","journal-title":"Lancet"},{"key":"2026021210022314000_nuaf053-B4","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.1016\/S0140-6736(11)60105-0","article-title":"Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies","volume":"377","author":"Wormser","year":"2011","journal-title":"Lancet"},{"key":"2026021210022314000_nuaf053-B5","doi-asserted-by":"publisher","first-page":"30","DOI":"10.2174\/1573402115666190415154603","article-title":"Hypertension in obesity: novel insights","volume":"16","author":"Natsis","year":"2020","journal-title":"Curr Hypertens Rev"},{"key":"2026021210022314000_nuaf053-B6","doi-asserted-by":"publisher","first-page":"e0194127","DOI":"10.1371\/journal.pone.0194127","article-title":"Risk factors for type 2 diabetes mellitus: an exposure-wide umbrella review of meta-analyses","volume":"13","author":"Bellou","year":"2018","journal-title":"PLoS One"},{"key":"2026021210022314000_nuaf053-B7","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.metabol.2018.11.001","article-title":"Obesity and cancer risk: emerging biological mechanisms and perspectives","volume":"92","author":"Avgerinos","year":"2019","journal-title":"Metabolism"},{"key":"2026021210022314000_nuaf053-B8","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.jacc.2017.11.011","article-title":"Obesity: pathophysiology and management","volume":"71","author":"Gadde","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"2026021210022314000_nuaf053-B9","doi-asserted-by":"publisher","first-page":"e97834","DOI":"10.1371\/journal.pone.0097834","article-title":"Weight-loss strategies used by the general population: how are they perceived?","volume":"9","author":"Julia","year":"2014","journal-title":"PLoS One"},{"key":"2026021210022314000_nuaf053-B10","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1093\/ajcn\/74.5.579","article-title":"Long-term weight-loss maintenance: a meta-analysis of US studies","volume":"74","author":"Anderson","year":"2001","journal-title":"Am J Clin Nutr"},{"key":"2026021210022314000_nuaf053-B11","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1002\/oby.20967","article-title":"NIH Working Group report: innovative research to improve maintenance of weight loss","volume":"23","author":"MacLean","year":"2015","journal-title":"Obesity (Silver Spring)"},{"key":"2026021210022314000_nuaf053-B12","doi-asserted-by":"publisher","first-page":"2985","DOI":"10.1016\/j.jacc.2013.11.004","article-title":"2013 AHA\/ACC\/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines and the Obesity Society","volume":"63(","author":"Jensen","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"2026021210022314000_nuaf053-B13","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1038\/ijo.2014.214","article-title":"Fasting for weight loss: an effective strategy or latest dieting trend?","volume":"39","author":"Johnstone","year":"2015","journal-title":"Int J Obes (Lond)"},{"key":"2026021210022314000_nuaf053-B14","doi-asserted-by":"publisher","DOI":"10.3390\/nu11040873","article-title":"Clinical management of intermittent fasting in patients with diabetes mellitus","volume":"11","author":"Grajower","year":"2019","journal-title":"Nutrients"},{"key":"2026021210022314000_nuaf053-B15","doi-asserted-by":"publisher","first-page":"2541","DOI":"10.1056\/NEJMra1905136","article-title":"Effects of intermittent fasting on health, aging, and disease","volume":"381","author":"de Cabo","year":"2019","journal-title":"N Engl J Med"},{"key":"2026021210022314000_nuaf053-B16","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1186\/s12986-021-00613-9","article-title":"Time-restricted feeding improves blood glucose and insulin sensitivity in overweight patients with type 2 diabetes: a randomised controlled trial","volume":"18","author":"Che","year":"2021","journal-title":"Nutr Metab (Lond)"},{"key":"2026021210022314000_nuaf053-B17","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.arr.2016.10.005","article-title":"Impact of intermittent fasting on health and disease processes","volume":"39","author":"Mattson","year":"2017","journal-title":"Ageing Res Rev"},{"key":"2026021210022314000_nuaf053-B18","doi-asserted-by":"publisher","first-page":"1491","DOI":"10.1001\/jamainternmed.2020.4153","article-title":"Effects of time-restricted eating on weight loss and other metabolic parameters in women and men with overweight and obesity: the TREAT randomized clinical trial","volume":"180","author":"Lowe","year":"2020","journal-title":"JAMA Intern Med"},{"key":"2026021210022314000_nuaf053-B19","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1016\/j.jand.2015.02.018","article-title":"Intermittent fasting and human metabolic health","volume":"115","author":"Patterson","year":"2015","journal-title":"J Acad Nutr Diet"},{"key":"2026021210022314000_nuaf053-B20","doi-asserted-by":"publisher","first-page":"2442","DOI":"10.3390\/nu11102442","article-title":"Effectiveness of intermittent fasting and time-restricted feeding compared to continuous energy restriction for weight loss","volume":"11","author":"Rynders","year":"2019","journal-title":"Nutrients"},{"key":"2026021210022314000_nuaf053-B21","doi-asserted-by":"publisher","first-page":"4911","DOI":"10.3390\/nu15234911","article-title":"Effectiveness of time-restricted eating with caloric restriction vs. caloric restriction for weight loss and health: meta-analysis","volume":"15","author":"\u010cre\u0161novar","year":"2023","journal-title":"Nutrients"},{"key":"2026021210022314000_nuaf053-B22","doi-asserted-by":"publisher","DOI":"10.1017\/S002966512400747X","article-title":"Effects of time-restricted eating on body composition, biomarkers of metabolism, inflammation, circadian system and oxidative stress in overweight and obesity: an exploratory review","author":"Lages","journal-title":"Proc Nutr Soc"},{"key":"2026021210022314000_nuaf053-B23","doi-asserted-by":"publisher","DOI":"10.3390\/nu13051430","article-title":"Time-restricted eating improves quality of life measures in overweight humans","author":"Crose","journal-title":"Nutrients"},{"key":"2026021210022314000_nuaf053-B24","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/j.cmet.2018.08.004","article-title":"Time-restricted feeding prevents obesity and metabolic syndrome in mice lacking a circadian clock","volume":"29","author":"Chaix","year":"2019","journal-title":"Cell Metab"},{"key":"2026021210022314000_nuaf053-B25","doi-asserted-by":"publisher","DOI":"10.3390\/nu13051405","article-title":"Beneficial effects of early time-restricted feeding on metabolic diseases: importance of aligning food habits with the circadian clock","author":"Charlot","journal-title":"Nutrients"},{"key":"2026021210022314000_nuaf053-B26","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1146\/annurev-nutr-082018-124320","article-title":"Time-restricted eating to prevent and manage chronic metabolic diseases","volume":"39","author":"Chaix","year":"2019","journal-title":"Annu Rev Nutr"},{"key":"2026021210022314000_nuaf053-B27","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1001\/jamainternmed.2017.0936","article-title":"Effect of alternate-day fasting on weight loss, weight maintenance, and cardioprotection among metabolically healthy obese adults: a randomized clinical trial","volume":"177","author":"Trepanowski","year":"2017","journal-title":"JAMA Intern Med"},{"key":"2026021210022314000_nuaf053-B28","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1002\/oby.23577","article-title":"The effects of time-restricted eating and weight loss on bone metabolism and health: a 6-month randomized controlled trial","volume":"31(Suppl 1)","author":"Papageorgiou","year":"2023","journal-title":"Obesity (Silver Spring)"},{"key":"2026021210022314000_nuaf053-B29","doi-asserted-by":"publisher","DOI":"10.3390\/nu13031042","article-title":"The effects of time-restricted eating versus standard dietary advice on weight, metabolic health and the consumption of processed food: a pragmatic randomised controlled trial in community-based adults","author":"Phillips","journal-title":"Nutrients"},{"key":"2026021210022314000_nuaf053-B30","doi-asserted-by":"publisher","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"2026021210022314000_nuaf053-B31","author":"Higgins","year":"2022"},{"key":"2026021210022314000_nuaf053-B32","author":"Elmagarmid"},{"key":"2026021210022314000_nuaf053-B33","author":"Cochrane","year":"2020"},{"key":"2026021210022314000_nuaf053-B34","doi-asserted-by":"publisher","first-page":"d5928","DOI":"10.1136\/bmj.d5928","article-title":"The Cochrane Collaboration\u2019s tool for assessing risk of bias in randomised trials","volume":"343","author":"Higgins","year":"2011","journal-title":"BMJ"},{"key":"2026021210022314000_nuaf053-B35","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"key":"2026021210022314000_nuaf053-B36","doi-asserted-by":"publisher","first-page":"1","DOI":"10.12707\/RV21077","article-title":"How to measure and explore heterogeneity in a meta-analysis: key methodological strategies","volume":"6","author":"Santos","year":"2022","journal-title":"Rev Enfermagem Referencia"},{"key":"2026021210022314000_nuaf053-B37","doi-asserted-by":"publisher","first-page":"775","DOI":"10.5123\/s1679-49742014000400021","article-title":"Heterogeneidade e vi\u00e9s de publica\u00e7\u00e3o em revis\u00f5es sistem\u00e1ticas","volume":"23","author":"Pereira","year":"2014","journal-title":"Epidemiol Serv Sa\u00fade"},{"key":"2026021210022314000_nuaf053-B38","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1002\/oby.23637","article-title":"Eight-hour time-restricted eating does not lower daily myofibrillar protein synthesis rates: a randomized control trial","volume":"31(Suppl 1)","author":"Parr","year":"2023","journal-title":"Obesity (Silver Spring)"},{"key":"2026021210022314000_nuaf053-B39","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1016\/j.clnu.2020.06.036","article-title":"Effects of time-restricted feeding on body weight, body composition and vital signs in low-income women with obesity: a 12-month randomized clinical trial","volume":"40","author":"de Oliveira Maranh\u00e3o Pureza","year":"2021","journal-title":"Clin Nutr"},{"key":"2026021210022314000_nuaf053-B40","doi-asserted-by":"publisher","first-page":"S39","DOI":"10.1016\/s0261-5614(16)30332-6","article-title":"PT09.1: Time restricted feeding (TRF) enhances weight loss efficiency in dietary restricted women with metabolic syndrome","volume":"35","author":"Amodio","year":"2016","journal-title":"Clin Nutr"},{"key":"2026021210022314000_nuaf053-B41","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1002\/oby.23620","article-title":"Time-restricted eating did not alter insulin sensitivity or \u03b2-cell function in adults with obesity: a randomized pilot study","volume":"31(Suppl 1)","author":"Bantle","year":"2023","journal-title":"Obesity (Silver Spring)"},{"key":"2026021210022314000_nuaf053-B42","doi-asserted-by":"publisher","first-page":"E185","DOI":"10.1097\/jnr.0000000000000469","article-title":"Intermittent fasting in weight loss and cardiometabolic risk reduction: a randomized controlled trial","volume":"30","author":"Chair","year":"2022","journal-title":"J Nurs Res"},{"key":"2026021210022314000_nuaf053-B43","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1002\/oby.22756","article-title":"Time-restricted eating effects on body composition and metabolic measures in humans who are overweight: a feasibility study","volume":"28","author":"Chow","year":"2020","journal-title":"Obesity (Silver Spring)"},{"key":"2026021210022314000_nuaf053-B44","doi-asserted-by":"publisher","DOI":"10.3390\/nu13051430","article-title":"Time-restricted eating improves quality of life measures in overweight humans","volume":"13","author":"Crose","year":"2021","journal-title":"Nutrients"},{"key":"2026021210022314000_nuaf053-B45","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/ijerph17114138","article-title":"Effect of a six-week intermittent fasting intervention program on the composition of the human body in women over 60 years of age","volume":"17","author":"Domaszewski","year":"2020","journal-title":"Int J Environ Res Public Health"},{"key":"2026021210022314000_nuaf053-B46","doi-asserted-by":"publisher","first-page":"345","DOI":"10.3233\/NHA-170036","article-title":"Effects of 8-hour time restricted feeding on body weight and metabolic disease risk factors in obese adults: a pilot study","volume":"4","author":"Gabel","year":"2018","journal-title":"Nutr Healthy Aging"},{"key":"2026021210022314000_nuaf053-B47","doi-asserted-by":"publisher","first-page":"e14868","DOI":"10.14814\/phy2.14868","article-title":"Time-restricted eating and concurrent exercise training reduces fat mass and increases lean mass in overweight and obese adults","volume":"9","author":"Kotarsky","year":"2021","journal-title":"Physiol Rep"},{"key":"2026021210022314000_nuaf053-B48","doi-asserted-by":"crossref","first-page":"111504","DOI":"10.1016\/j.nut.2021.111504","article-title":"Effect of time-restricted feeding on body composition and cardio-metabolic risk in middle-aged women in Taiwan","volume":"93","author":"Lin","year":"2022","journal-title":"Nutrition"},{"key":"2026021210022314000_nuaf053-B49","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1093\/aje\/kwr140","article-title":"Evaluation and comparison of food records, recalls, and frequencies for energy and protein assessment by using recovery biomarkers","volume":"174","author":"Prentice","year":"2011","journal-title":"Am J Epidemiol"},{"key":"2026021210022314000_nuaf053-B50","doi-asserted-by":"publisher","DOI":"10.3390\/nu13041155","article-title":"Time-restricted eating for 12 weeks does not adversely alter bone turnover in overweight adults","volume":"13","author":"Lobene","year":"2021","journal-title":"Nutrients"},{"key":"2026021210022314000_nuaf053-B51","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1002\/oby.23637","article-title":"Eight-hour time-restricted eating does not lower daily myofibrillar protein synthesis rates: a randomized control trial","volume":"31(Suppl 1)","author":"Parr","year":"2023","journal-title":"Obesity (Silver Spring)"},{"key":"2026021210022314000_nuaf053-B52","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1002\/oby.23057","article-title":"Effect of time-restricted eating on weight, fat loss and cardiometabolic risk inadults with obesity","volume":"28","author":"Steger","year":"2020","journal-title":"Obesity"},{"key":"2026021210022314000_nuaf053-B53","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1093\/ajcn\/nqz126","article-title":"Time-restricted feeding plus resistance training in active females: a randomized trial","volume":"110","author":"Tinsley","year":"2019","journal-title":"Am J Clin Nutr"},{"key":"2026021210022314000_nuaf053-B54","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1002\/oby.23420","article-title":"Early time-restricted eating compared with daily caloric restriction: a randomized trial in adults with obesity","volume":"30","author":"Thomas","year":"2022","journal-title":"Obesity (Silver Spring)"},{"key":"2026021210022314000_nuaf053-B55","doi-asserted-by":"publisher","first-page":"111909","DOI":"10.1016\/j.nut.2022.111909","article-title":"Metabolic and behavioral effects of time-restricted eating in women with overweight or obesity: preliminary findings from a randomized study","volume":"107","author":"Fagundes","year":"2023","journal-title":"Nutrition"},{"key":"2026021210022314000_nuaf053-B56","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1001\/jamainternmed.2022.3050","article-title":"Effectiveness of early time-restricted eating for weight loss, fat loss, and cardiometabolic health in adults with obesity: a randomized clinical trial","volume":"182","author":"Jamshed","year":"2022","journal-title":"JAMA Intern Med"},{"key":"2026021210022314000_nuaf053-B57","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1038\/s41387-021-00149-0","article-title":"Effect of time restricted eating on body weight and fasting glucose in participants with obesity: results of a randomized, controlled, virtual clinical trial","volume":"11","author":"Peeke","year":"2021","journal-title":"Nutr Diabetes"},{"key":"2026021210022314000_nuaf053-B58","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1002\/oby.23614","article-title":"Early time-restricted eating affects weight, metabolic health, mood, and sleep in adherent completers: a secondary analysis","volume":"31(Suppl 1)","author":"Steger","year":"2023","journal-title":"Obesity (Silver Spring)"},{"key":"2026021210022314000_nuaf053-B59","doi-asserted-by":"publisher","first-page":"41","DOI":"10.30699\/jambs.28.126.41","article-title":"Effects of evening meal timing on weight loss: a pilot open-labelled randomized clinical trial","volume":"28","author":"Mansoori","year":"2020","journal-title":"J Adv Med Biomed Res"},{"key":"2026021210022314000_nuaf053-B60","doi-asserted-by":"publisher","first-page":"110796","DOI":"10.1016\/j.nut.2020.110796","article-title":"Acute effects of time-restricted feeding in low-income women with obesity placed on hypoenergetic diets: randomized trial","volume":"77","author":"Pureza","year":"2020","journal-title":"Nutrition"},{"key":"2026021210022314000_nuaf053-B61","doi-asserted-by":"publisher","DOI":"10.2337\/db19-2076-p","article-title":"2076-P: Time restricted eating (TRE) promotes weight loss, alters body composition, and improves metabolic parameters in overweight humans","volume":"68(Suppl 1):2076-P","author":"Chow","year":"2019","journal-title":"Diabetes"},{"key":"2026021210022314000_nuaf053-B62","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1177\/02601060211002347","article-title":"The effect of 4-h versus 6-h time restricted feeding on sleep quality, duration, insomnia severity and obstructive sleep apnea in adults with obesity","volume":"28","author":"Cienfuegos","year":"2022","journal-title":"Nutr Health"},{"key":"2026021210022314000_nuaf053-B63","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1016\/j.cmet.2020.06.018","article-title":"Effects of 4- and 6-h time-restricted feeding on weight and cardiometabolic health: a randomized controlled trial in adults with obesity","volume":"32","author":"Cienfuegos","year":"2020","journal-title":"Cell Metab"},{"key":"2026021210022314000_nuaf053-B64","doi-asserted-by":"publisher","DOI":"10.3390\/nu13093122","article-title":"The effects of a macronutrient-based diet and time-restricted feeding (16:8) on body composition in physically active individuals\u2014a 14-week randomised controlled trial","volume":"13","author":"Isenmann","year":"2021","journal-title":"Nutrients"},{"key":"2026021210022314000_nuaf053-B65","author":"Gabel","year":"2018"},{"key":"2026021210022314000_nuaf053-B66","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/ijerph17114138","article-title":"Effect of a six-week intermittent fasting intervention program on the composition of the human body in women over 60 years of age","volume":"17","author":"Domaszewski","year":"2020","journal-title":"Int J Environ Res Public Health"},{"key":"2026021210022314000_nuaf053-B67","doi-asserted-by":"publisher","DOI":"10.3390\/nu13041155","article-title":"Time-restricted eating for 12 weeks does not adversely alter bone turnover in overweight adults","volume":"13","author":"Lobene","year":"2021","journal-title":"Nutrients"},{"key":"2026021210022314000_nuaf053-B68","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1002\/oby.23620","article-title":"Time-restricted eating did not alter insulin sensitivity or \u03b2-cell function in adults with obesity: a randomized pilot study","volume":"31(Suppl 1)","author":"Bantle","year":"2023","journal-title":"Obesity (Silver Spring)"},{"key":"2026021210022314000_nuaf053-B69","doi-asserted-by":"publisher","first-page":"898792","DOI":"10.3389\/fphys.2022.898792","article-title":"Calorie restriction rescues mitochondrial dysfunction in Adck2-deficient skeletal muscle","volume":"13","author":"Hern\u00e1ndez-Camacho","year":"2022","journal-title":"Front Physiol"},{"key":"2026021210022314000_nuaf053-B70","doi-asserted-by":"publisher","first-page":"101684","DOI":"10.1016\/j.molmet.2023.101684","article-title":"Targeting negative energy balance with calorie restriction and mitochondrial uncoupling in db\/db mice","volume":"69","author":"Chen","year":"2023","journal-title":"Mol Metab"},{"key":"2026021210022314000_nuaf053-B71","doi-asserted-by":"publisher","DOI":"10.3390\/nu12040930","article-title":"Calorie restriction improves physical performance and modulates the antioxidant and inflammatory responses to acute exercise","volume":"12","author":"Cap\u00f3","year":"2020","journal-title":"Nutrients"},{"key":"2026021210022314000_nuaf053-B72","doi-asserted-by":"publisher","first-page":"95","DOI":"10.3390\/geriatrics5040095","article-title":"Nutrients and pathways that regulate health span and life span","volume":"5","author":"Pignatti","year":"2020","journal-title":"Geriatrics (Switzerland)"},{"key":"2026021210022314000_nuaf053-B73","doi-asserted-by":"publisher","DOI":"10.3390\/nu13041302","article-title":"Effects of calorie restriction on health span and insulin resistance: classic calorie restriction diet vs. ketosis-inducing diet","volume":"13","author":"Napole\u00e3o","year":"2021","journal-title":"Nutrients"},{"key":"2026021210022314000_nuaf053-B74","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1002\/fsn3.3194","article-title":"Is time-restricted eating (8\/16) beneficial for body weight and metabolism of obese and overweight adults? A systematic review and meta-analysis of randomized controlled trials","volume":"11","author":"Huang","year":"2023","journal-title":"Food Sci Nutr"},{"key":"2026021210022314000_nuaf053-B75","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1080\/10408398.2021.1974335","article-title":"Missing puzzle pieces of time-restricted-eating (TRE) as a long-term weight-loss strategy in overweight and obese people? A systematic review and meta-analysis of randomized controlled trials","volume":"63","author":"Chen","year":"2023","journal-title":"Crit Rev Food Sci Nutr"},{"key":"2026021210022314000_nuaf053-B76","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/nu12123770","article-title":"Food timing, circadian rhythm and chrononutrition: a systematic review of time-restricted eating\u2019s effects on human health","volume":"12","author":"R\u00e9da","year":"2020","journal-title":"Nutrients"},{"key":"2026021210022314000_nuaf053-B77","doi-asserted-by":"publisher","DOI":"10.3390\/nu13051405","article-title":"Beneficial effects of early time-restricted feeding on metabolic diseases: importance of aligning food habits with the circadian clock","volume":"13","author":"Charlot","year":"2021","journal-title":"Nutrients"},{"key":"2026021210022314000_nuaf053-B78","doi-asserted-by":"publisher","first-page":"3428","DOI":"10.1210\/clinem\/dgac570","article-title":"Metabolic efficacy of time-restricted eating in adults: a systematic review and meta-analysis of randomized controlled trials","volume":"107","author":"Liu","year":"2022","journal-title":"J Clin Endocrinol Metab"},{"key":"2026021210022314000_nuaf053-B79","doi-asserted-by":"publisher","first-page":"1572","DOI":"10.1056\/nejme2202821","article-title":"Calorie and time restriction in weight loss","volume":"386","author":"Laferr\u00e8re","year":"2022","journal-title":"N Engl J Med"},{"key":"2026021210022314000_nuaf053-B80","doi-asserted-by":"publisher","DOI":"10.3390\/nu11102442","article-title":"Effectiveness of intermittent fasting and time-restricted feeding compared to continuous energy restriction for weight loss","volume":"11","author":"Rynders","year":"2019","journal-title":"Nutrients"},{"key":"2026021210022314000_nuaf053-B81","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/nu12030874","article-title":"Determinants of adherence in time-restricted feeding in older adults: lessons from a pilot study","volume":"12","author":"Lee","year":"2020","journal-title":"Nutrients"}],"container-title":["Nutrition Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/nutritionreviews\/article-pdf\/84\/3\/463\/63028472\/nuaf053.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/nutritionreviews\/article-pdf\/84\/3\/463\/63028472\/nuaf053.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T15:02:29Z","timestamp":1770908549000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/nutritionreviews\/article\/84\/3\/463\/8121825"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,29]]},"references-count":81,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,4,29]]},"published-print":{"date-parts":[[2026,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/nutrit\/nuaf053","relation":{},"ISSN":["0029-6643","1753-4887"],"issn-type":[{"value":"0029-6643","type":"print"},{"value":"1753-4887","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,3]]},"published":{"date-parts":[[2025,4,29]]}}}