{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T10:23:17Z","timestamp":1789122197383,"version":"build-2803163510"},"reference-count":101,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:00:00Z","timestamp":1756339200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Context<\/jats:title>\n                    <jats:p>Bitter taste sensitivity plays a role in dietary preferences and food intake, potentially affecting weight status. Despite previous studies performed to investigate this role, the relationship between bitter taste sensitivity and anthropometric measures remains inconclusive.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>In this review we sought to systematically evaluate the association between sensitivity to bitter taste and weight status in adults through a comprehensive meta-analysis and meta-regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>We conducted a systematic search of the EMBASE, MEDLINE, CINAHL, Scopus, and PsycInfo databases for reported studies on this topic published up to March 2024. Included studies involved healthy adults and were published in English.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Extraction<\/jats:title>\n                    <jats:p>Two reviewers independently screened titles, abstracts, and full texts. Data on study characteristics, methods of assessing taste sensitivity, and anthropometric outcomes were extracted. Quality assessment was performed using the American Dietetic Association Quality Criteria Checklist.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Analysis<\/jats:title>\n                    <jats:p>Meta-analysis of 27 studies (80 effect estimates) revealed no significant association between bitter taste sensitivity and overall weight status (Cohen\u2019s dz, \u22120.02; 95% CI, \u22120.10 to 0.05, P\u2009=\u2009.58). Subgroup analyses also showed no significant differences between nontasters, medium tasters, and supertasters. Meta-regression indicated that the waist\u2013hip ratio was a significant moderator (P\u2009=\u2009.004). Heterogeneity was high (I2 = 91.5%), and publication bias was minimal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Bitter taste sensitivity does not significantly influence overall weight status but may affect body fat distribution. Methodological variability and population differences highlight the need for standardized protocols in future research. These findings contribute to understanding taste sensitivity in obesity prevention and dietary behavior strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/nutrit\/nuaf160","type":"journal-article","created":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T07:35:45Z","timestamp":1751960145000},"page":"84-98","source":"Crossref","is-referenced-by-count":2,"title":["Association between Bitter Taste Sensitivity and Weight Status in Adults: A Systematic Review and Meta-Analysis"],"prefix":"10.1093","volume":"84","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2017-927X","authenticated-orcid":false,"given":"Alia","family":"Shareef","sequence":"first","affiliation":[{"name":"School of Allied Health, Sport and Social Work, Griffith University , Gold Coast, Queensland 4222,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4173-3759","authenticated-orcid":false,"given":"Getahun Fentaw","family":"Mulaw","sequence":"additional","affiliation":[{"name":"School of Pharmacy and Medical Science, Griffith University , Gold Coast, Queensland 4222,","place":["Australia"]},{"name":"Department of Public Health, College of Health Sciences, Woldia University , Woldia 6040, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4463-6871","authenticated-orcid":false,"given":"Kruti","family":"Rathore","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Dietetics, Bangalore University , Bengaluru 560056,","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1379-4271","authenticated-orcid":false,"given":"Chris","family":"Irwin","sequence":"additional","affiliation":[{"name":"School of Allied Health, Sport and Social Work, Griffith University , Gold Coast, Queensland 4222,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0669-7147","authenticated-orcid":false,"given":"Lisa","family":"Vincze","sequence":"additional","affiliation":[{"name":"School of Allied Health, Sport and Social Work, Griffith University , Gold Coast, Queensland 4222,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4829-8371","authenticated-orcid":false,"given":"Roshan","family":"Rigby","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences and Medicine, Bond University , Gold Coast, Queensland 4229,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0915-4420","authenticated-orcid":false,"given":"Rati","family":"Jani","sequence":"additional","affiliation":[{"name":"School of Allied Health, Sport and Social Work, Griffith University , Gold Coast, Queensland 4222,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,8,28]]},"reference":[{"key":"2025121102520876200_nuaf160-B1","author":"World Health Organization"},{"key":"2025121102520876200_nuaf160-B2","doi-asserted-by":"publisher","first-page":"1990","DOI":"10.1186\/s12889-021-12009-8","article-title":"The association between obesity and quality of life: a retrospective analysis of a large-scale population-based cohort study","volume":"21","author":"Stephenson","year":"2021","journal-title":"BMC Public Health"},{"key":"2025121102520876200_nuaf160-B3","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1467-789X.2009.00712.x","article-title":"The economic burden of obesity worldwide: a systematic review of the direct costs of obesity","volume":"12","author":"Withrow","year":"2011","journal-title":"Obes Rev"},{"key":"2025121102520876200_nuaf160-B4","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1016\/S0140-6736(16)30175-1","article-title":"Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents","volume":"388","author":"Di Angelantonio","year":"2016","journal-title":"Lancet"},{"key":"2025121102520876200_nuaf160-B5","doi-asserted-by":"crossref","first-page":"7","DOI":"10.4103\/SHB.SHB_37_18","article-title":"Economic burden of obesity: a systematic review","volume":"2","author":"Yusefzadeh","year":"2019","journal-title":"Asian J Soc Health Behav"},{"key":"2025121102520876200_nuaf160-B6","doi-asserted-by":"publisher","first-page":"1148","DOI":"10.1080\/02640414.2015.1093650","article-title":"What is really causing the obesity epidemic? 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