{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T18:08:16Z","timestamp":1791655696355,"version":"4.3.4"},"reference-count":61,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Context<\/jats:title>\n                    <jats:p>Obesity is a prevalent comorbidity in type 2 diabetes mellitus (T2DM) and contributes significantly to poor glycemic control and insulin resistance. Curcumin, a bioactive compound in turmeric, has shown potential in influencing body composition due to its anti-inflammatory and metabolic properties.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We sought to evaluate the effects of curcumin supplementation on body weight (BW), body mass index (BMI), and waist circumference (WC) in adults with T2DM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>A systematic literature search was performed in the PubMed, Scopus, Web of Science, and ISI databases up to January 2024. Reference lists of relevant articles and reviews were also screened manually.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Extraction<\/jats:title>\n                    <jats:p>Two independent reviewers (N.A. and S.A.) selected randomized controlled trials (RCTs) based on predefined inclusion criteria and extracted data on BW, BMI, and WC changes. The Cochrane risk-of-bias tool was used for quality assessment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Analysis<\/jats:title>\n                    <jats:p>Nine RCTs involving 699 participants were included. Pooled estimates were calculated using a random-effects model. Curcumin supplementation significantly reduced BW (weighted mean difference [WMD], \u20131.65\u2009kg), BMI (WMD, \u20130.69\u2009kg\/m2), and WC (WMD, \u20130.93\u2009cm). Subgroup analyses indicated greater reductions at doses &amp;gt;1000\u2009mg\/d.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Curcumin supplementation may beneficially affect body composition parameters in T2DM patients, particularly at higher doses. Further high-quality RCTs are warranted to confirm long-term benefits and clinical significance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Systematic Review Registration<\/jats:title>\n                    <jats:p>This review was not registered in PROSPERO.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/nutrit\/nuaf193","type":"journal-article","created":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T11:49:25Z","timestamp":1762775365000},"page":"1535-1548","source":"Crossref","is-referenced-by-count":6,"title":["The Effects of Curcumin Supplementation on Body Weight, Body Mass Index, and Waist Circumference in Patients With Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials"],"prefix":"10.1093","volume":"84","author":[{"given":"Noorbakhsh","family":"Alivand","sequence":"first","affiliation":[{"name":"Nutrition Research Center, Department of Clinical Nutrition, School of 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