{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T20:51:36Z","timestamp":1792702296278,"version":"4.5.0"},"reference-count":48,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2022,1,22]],"date-time":"2022-01-22T00:00:00Z","timestamp":1642809600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,4,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Raynaud\u2019s phenomenon (RP) is a recognized symptom associated with carpal tunnel syndrome (CTS) and is also the vascular manifestation of hand arm vibration syndrome (HAVS). The symptoms of HAVS and CTS are such that there is a significant possibility of misdiagnosis and an incorrect attribution of vascular and sensory symptoms. An understanding of the relationship between RP and CTS is essential when undertaking health surveillance of vibration-exposed workers presenting with combined vascular and sensory symptoms.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>To clarify the relationship between CTS and Raynaud\u2019s phenomenon.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A systematic search was undertaken of studies that reviewed links between CTS and Raynaud\u2019s phenomenon (RP).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 4170 papers were identified, with 21 articles that were then reviewed in full, including 1 meta-analysis of 8 studies. Eighteen papers, not included in the meta-analysis, were found including 3 case control studies, 9 case reports, 2 prospective studies and 4 retrospective reviews. Papers were reviewed on the basis of the diagnostic criteria used for CTS and RP. Our review of the literature confirms a substantial body of evidence of a relationship between RP and CTS.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>It is recommended that assessment of vibration exposed individuals who report concurrent RP and separate sensory symptoms suggestive of, or compatible with CTS, should formally exclude CTS before attributing symptoms to HAVS.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/occmed\/kqab158","type":"journal-article","created":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T19:10:26Z","timestamp":1634843426000},"page":"170-176","source":"Crossref","is-referenced-by-count":11,"title":["Carpal tunnel syndrome and Raynaud\u2019s phenomenon: a narrative review"],"prefix":"10.1093","volume":"72","author":[{"given":"Roger","family":"Cooke","sequence":"first","affiliation":[{"name":"Institute of Occupational and Environmental Medicine, University of Birmingham, Birmingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Lawson","sequence":"additional","affiliation":[{"name":"Occupational Health Physician (ret\u2019d), Belper, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanna","family":"Gillibrand","sequence":"additional","affiliation":[{"name":"Independent Occupational Physician, Southampton,UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Cooke","sequence":"additional","affiliation":[{"name":"Clarity Healthcare Ltd, Stockport, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,1,22]]},"reference":[{"key":"2022041911054975300_CIT0001","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1136\/bmj.1.5021.730","article-title":"Compression of median nerve in carpal tunnel and its relation to acroparaesthesiae","volume":"1","author":"Garland","year":"1957","journal-title":"Br Med J"},{"key":"2022041911054975300_CIT0002","first-page":"952","article-title":"Carpal tunnel syndrome","volume":"83","author":"LeBlanc","year":"2011","journal-title":"Am Fam Physician"},{"key":"2022041911054975300_CIT0003","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1093\/rheumatology\/37.6.630","article-title":"Estimating the prevalence of delayed median nerve conduction in the general population","volume":"37","author":"Ferry","year":"1998","journal-title":"Br J Rheumatol"},{"key":"2022041911054975300_CIT0004","article-title":"(1836) Arch gen de med XL: 187.","author":"Genoul."},{"key":"2022041911054975300_CIT0005","article-title":"Lectures on Surgical Pathology at the Royal College of Surgeons of England Philadelphia","author":"Paget","year":"1854"},{"key":"2022041911054975300_CIT0006","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-540-49008-1_1","article-title":"History of Carpal Tunnel Syndrome.","volume-title":"Carpal Tunnel Syndrome","author":"Amadio","year":"2007"},{"key":"2022041911054975300_CIT0007","first-page":"7","article-title":"The effect of repetitive wrist loads in Athletes on Median Nerve Neurophysiological evaluation","volume":"3","author":"Abdulrazzaq","year":"2016","journal-title":"J Sports Phys Ed"},{"key":"2022041911054975300_CIT0008","first-page":"4","article-title":"Pathophysiology of carpal tunnel syndrome","volume":"20","author":"Abbonq","year":"2015","journal-title":"Neurosciences"},{"key":"2022041911054975300_CIT0009","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1136\/oem.55.4.264","article-title":"Surveillance case definitions for work related upper limb pain syndromes","volume":"55","author":"Harrington","year":"1998","journal-title":"Occup Environ Med"},{"key":"2022041911054975300_CIT0010","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/S0025-6196(12)61756-X","article-title":"The many faces of carpal tunnel syndrome","volume":"64","author":"Spinner","year":"1989","journal-title":"Mayo Clin Proc"},{"key":"2022041911054975300_CIT0011","doi-asserted-by":"crossref","DOI":"10.1093\/occmed\/kqaa118","article-title":"Non-classical presentation of carpal tunnel syndrome","author":"Cooke","year":"2021","journal-title":"Occup Med (Lond)"},{"key":"2022041911054975300_CIT0012","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1308\/003588411X586191","article-title":"Often atypical? 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