{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T08:31:22Z","timestamp":1774513882502,"version":"3.50.1"},"reference-count":64,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T00:00:00Z","timestamp":1737072000000},"content-version":"vor","delay-in-days":47,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Exposure to strong inorganic acid mists (SIAMs) in the workplace has been linked to respiratory tract cancers.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>We conducted a meta-analysis of cohort and case\u2013control studies examining the association between occupational SIAMs and respiratory tract cancers other than laryngeal cancer, which is already established.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Studies mentioned in the 1992 IARC Monograph on carcinogenicity of SIAMs were combined with later studies identified from a systematic search of Scopus, PubMed and Embase. Forest plots of relative risks (RR) and odds ratios were constructed for the 34 identified studies. A random-effects model was used to address heterogeneity.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>An association between the roles associated with occupational SIAMs exposure and risk of lung (RR\u2005=\u20051.17; 95% confidence interval [CI]\u2005=\u20051.05\u20131.32), and nasal cancers (RR\u2005=\u20053.30, 95% CI\u2005=\u20051.16\u20139.41) was found. The risk of oral and pharyngeal cancer was also associated with SIAMs exposure-related roles (RR\u2005=\u20051.59, 95% CI\u2005=\u20050.98\u20132.57). Results did not differ by study design, gender or outcome for all three cancers. A positive association for lung cancer was found with chemical (RR\u2005=\u20051.25, 95% CI\u2005=\u20051.13\u20131.38), and metal and steel industries (RR\u2005=\u20051.19, 95% CI\u2005=\u20051.04\u20131.37), as well as for oral and pharyngeal cancer with chemical industry (RR\u2005=\u20051.72, 95% CI\u2005=\u20051.57\u20131.89). We checked publication bias for lung (p\u2005=\u20050.35), oral and pharyngeal (p\u2005=\u20050.02) and nasal cancer (p\u2005=\u20050.40).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Our study showed an association between occupational SIAM exposure and risk of lung, nasal, and possibly oral and pharyngeal cancers. However, weaknesses in the recording of confounding and exposure data in the currently available literature were found.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/occmed\/kqae089","type":"journal-article","created":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T23:18:11Z","timestamp":1727911091000},"page":"632-638","source":"Crossref","is-referenced-by-count":3,"title":["Strong inorganic acid mists and respiratory tract cancers: a meta-analysis"],"prefix":"10.1093","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9063-9128","authenticated-orcid":false,"given":"M S","family":"Seyyedsalehi","sequence":"first","affiliation":[{"name":"Department of Medical and Surgical Sciences, University of Bologna , Bologna ,","place":["Italy"]},{"name":"Cancer Research Center, Cancer Institute, Tehran University of Medical Sciences , Tehran ,","place":["Iran"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Di Lorenzo","sequence":"additional","affiliation":[{"name":"Interdisciplinary Department of Medicine, University of Bari , 70124 Bari ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4072-2871","authenticated-orcid":false,"given":"L","family":"Vimercati","sequence":"additional","affiliation":[{"name":"Interdisciplinary Department of Medicine, University of Bari , 70124 Bari ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Boffetta","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences, University of Bologna , Bologna ,","place":["Italy"]},{"name":"Stony Brook Cancer Center, Stony Brook University , Stony Brook, NY ,","place":["USA"]},{"name":"Department of Family, Population and Preventive Medicine, Renaissance School of Medicine, Stony Brook University , Stony Brook, NY ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,1,16]]},"reference":[{"key":"2025071807515116200_CIT0001","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global Cancer Statistics 2020: GLOBOCAN estimates incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"2025071807515116200_CIT0002","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1183\/13993003.00359-2016","article-title":"Risk factors for lung cancer worldwide","volume":"48","author":"Malhotra","year":"2016","journal-title":"Eur Respir J"},{"key":"2025071807515116200_CIT0003","first-page":"42","article-title":"Epidemiology, risk factors, and prevention of head and neck squamous cell carcinoma","volume":"11","author":"Barsouk","year":"2023","journal-title":"Med Sci"},{"key":"2025071807515116200_CIT0004","first-page":"3","volume-title":"Aerosol Technology. 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