{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T06:57:21Z","timestamp":1780556241073,"version":"3.54.1"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:00:00Z","timestamp":1756339200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.nationalarchives.gov.uk\/doc\/open-government-licence\/version\/3\/"}],"funder":[{"DOI":"10.13039\/501100000869","name":"Health and Safety Executive","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000869","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The relationship between pesticide exposure and respiratory ill-health remains under researched.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>We set out to define the prevalence of respiratory complaints, excluding asthma, and estimates of exposure in a cohort of pesticide applicators based in Great Britain (GB).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A baseline cross-sectional study (n\u2005=\u20055817), with follow-up at up to 5 years (n\u2005=\u20052578), was conducted in GB pesticide workers. Demographic and personal factors, details of working hours and practices, exposures to specific pesticide types, self-reported respiratory ill-health and doctor-diagnosed health conditions were recorded. Multivariable logistic regression models were used to assess the association between exposures to pesticides and respiratory health.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The mean age was 54.1 years; 98% were male. At baseline, 70 (1.2%) had doctor-diagnosed chronic bronchitis, and 60 (1%) had chronic obstructive pulmonary disease (COPD). Twenty-six (0.4%) reported farmer\u2019s lung. In contrast, reported respiratory symptoms were common at follow-up; nasal allergies reported by 541 participants (21%), regular cough by 351 (14%), chest tightness ever by 329 (13%) and work-related chest tightness by 45 (1.8%). Nasal allergies were more common in those not using pesticides in the last 12 months [odds ratio (OR) 1.54 (95% CI 1.14\u20132.06)], chest tightness was more common in retired workers [OR 1.87 (1.25\u20132.81)], and work-related chest tightness more common in the current high exposure category [OR 2.68 (1.28\u20135.60)].<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This study has confirmed low levels of self-reported doctor-diagnosed conditions, but high levels of reported respiratory symptoms. This suggests potential under diagnosis of respiratory ill-health in this sector.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/occmed\/kqaf029","type":"journal-article","created":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:13:06Z","timestamp":1756339986000},"page":"403-411","source":"Crossref","is-referenced-by-count":2,"title":["Respiratory conditions and pesticide exposure in British pesticide applicators"],"prefix":"10.1093","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5941-090X","authenticated-orcid":false,"given":"D","family":"Fishwick","sequence":"first","affiliation":[{"name":"HSE Science and Research Centre, Health and Safety Executive (HSE) , Buxton, Derbyshire SK17 9JN ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A H","family":"Harding","sequence":"additional","affiliation":[{"name":"HSE Science and Research Centre, Health and Safety Executive (HSE) , Buxton, Derbyshire SK17 9JN ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4218-084X","authenticated-orcid":false,"given":"Y","family":"Chen","sequence":"additional","affiliation":[{"name":"HSE Science and Research Centre, Health and Safety Executive (HSE) , Buxton, Derbyshire SK17 9JN ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C M","family":"Barber","sequence":"additional","affiliation":[{"name":"HSE Science and Research Centre, Health and Safety Executive (HSE) , Buxton, Derbyshire SK17 9JN ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9938-7852","authenticated-orcid":false,"given":"N","family":"Pearce","sequence":"additional","affiliation":[{"name":"London School of Hygiene and Tropical Medicine, Keppel Street , London WC1E 7HT 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