{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T05:43:51Z","timestamp":1764913431700,"version":"3.46.0"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T00:00:00Z","timestamp":1756944000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>Caplan syndrome, a rare condition characterized by the coexistence of pneumoconiosis and rheumatoid arthritis in individuals exposed to inorganic dust, remains a relevant diagnostic consideration in the 21st century. We present a case of a 41-year-old former coal miner who developed multiple cavitary pulmonary nodules years after leaving the mining sector, initially mimicking pulmonary malignancy. Extensive diagnostic work-up, including positron emission tomography-computed tomography, bronchoscopy and lung biopsy, eventually led to the diagnosis of Caplan syndrome, with seropositive rheumatoid arthritis emerging 8 years after exposure cessation. This case highlights the delayed autoimmune effects of occupational inhalants and underscores the ongoing need for vigilance and improved occupational health measures in high-risk industries.<\/jats:p>","DOI":"10.1093\/occmed\/kqaf094","type":"journal-article","created":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T11:52:00Z","timestamp":1755690720000},"page":"535-539","source":"Crossref","is-referenced-by-count":0,"title":["Caplan syndrome in the 21st century: Cavitary nodules and delayed rheumatoid arthritis"],"prefix":"10.1093","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6514-6789","authenticated-orcid":false,"given":"Y S","family":"Hasanli","sequence":"first","affiliation":[{"name":"Department of Internal Diseases, Occupational Diseases Unit, Ministry of Health Ankara Etlik City Hospital , Ankara,","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,9,4]]},"reference":[{"key":"2025120500420893800_kqaf094-B1","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.ejim.2010.02.004","article-title":"Rheumatoid pneumoconiosis (Caplan\u2019s syndrome)","volume":"21","author":"Schreiber","year":"2010","journal-title":"Eur J Intern Med"},{"key":"2025120500420893800_kqaf094-B2","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1136\/thx.8.1.29","article-title":"Certain unusual radiological appearances in the chest of coal miners suffering from rheumatoid arthritis","volume":"8","author":"Caplan","year":"1953","journal-title":"Thorax"},{"volume-title":"StatPearls [Internet]","year":"2025","author":"Nemakayala","key":"2025120500420893800_kqaf094-B3"},{"key":"2025120500420893800_kqaf094-B4","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1016\/j.radcr.2018.03.004","article-title":"A case of Caplan syndrome in a recently diagnosed patient with silicosis: a case report","volume":"13","author":"Alaya","year":"2018","journal-title":"Radiol Case Rep"},{"key":"2025120500420893800_kqaf094-B5","doi-asserted-by":"publisher","DOI":"10.31579\/2690-4861\/007","article-title":"Caplan\u2019s syndrome with a twist","volume":"2","author":"Deepak","year":"2020","journal-title":"Int J Clin Case Rep Rev"},{"volume-title":"In: StatPearls [Internet].","year":"2025","author":"Baum","key":"2025120500420893800_kqaf094-B6"},{"key":"2025120500420893800_kqaf094-B7","doi-asserted-by":"publisher","first-page":"789","DOI":"10.3348\/jksr.2023.0128","article-title":"Caplan syndrome mimicking progressive massive fibrosis on CT: a case report","volume":"85","author":"Baek","year":"2024","journal-title":"J Korean Soc Radiol"},{"key":"2025120500420893800_kqaf094-B8","doi-asserted-by":"publisher","first-page":"91","DOI":"10.2147\/LCTT.S156376","article-title":"Silicosis and lung cancer: current perspectives","volume":"9","author":"Sato","year":"2018","journal-title":"Lung Cancer (Auckl)"},{"key":"2025120500420893800_kqaf094-B9","doi-asserted-by":"publisher","first-page":"383","DOI":"10.2174\/1574886317666220428132311","article-title":"Treatment with rituximab in rheumatoid pneumoconiosis: a case report","volume":"18","author":"Yasmine","year":"2023","journal-title":"Curr Drug Saf"},{"volume-title":"Diagnostic and Exposure Criteria for Occupational Diseases. Guidance Notes for Diagnosis and Prevention of the Diseases in the ILO List of Occupational Diseases","year":"2010","author":"International Labour Organization","key":"2025120500420893800_kqaf094-B10"},{"volume-title":"Pn\u00f6mokonyozlarda Sa\u011fl\u0131k G\u00f6zetimi, Klinik Tan\u0131, Kay\u0131t, Bildirim ve \u0130zlem Protokol\u00fc (Versiyon 1.0) [Health Surveillance, Clinical Diagnosis, Registration, Notification, and Follow-up Protocol for Pneumoconiosis (Version 1.0)].","year":"2021","author":"Sa\u011fl\u0131k Bakanl\u0131\u011f\u0131","key":"2025120500420893800_kqaf094-B11"}],"container-title":["Occupational Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/occmed\/article-pdf\/75\/8\/535\/64212110\/kqaf094.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/occmed\/article-pdf\/75\/8\/535\/64212110\/kqaf094.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T05:42:16Z","timestamp":1764913336000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/occmed\/article\/75\/8\/535\/8248158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,4]]},"references-count":11,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2025,9,4]]},"published-print":{"date-parts":[[2025,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/occmed\/kqaf094","relation":{},"ISSN":["0962-7480","1471-8405"],"issn-type":[{"type":"print","value":"0962-7480"},{"type":"electronic","value":"1471-8405"}],"subject":[],"published-other":{"date-parts":[[2025,11]]},"published":{"date-parts":[[2025,9,4]]}}}