{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:10:45Z","timestamp":1753877445919,"version":"3.41.2"},"reference-count":29,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"The National Advisory Unit for Rare Disorders"},{"name":"Frambu Competence Centre for Rare Disorders"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Neurofibromatosis type 1 (NF1) is a rare genetic disorder with usually benign nerve tumours, skin problems, pain and cardiovascular problems among common complications.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>To examine work participation and experiences in relation to health complaints among adults with NF1.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We conducted a cross-sectional self-reported survey among 142 persons with NF1 (mean age = 50.3 years, SD = 12.0; 62% females). We measured physical and social dimensions of work experiences with eight items from the third wave of the epidemiological survey \u2018Nord-Tr\u00f8ndelag Health Study\u2019 (HUNT3). We compared NF1 data to 27 036 HUNT3 controls. We measured health complaints with the 29-item Subjective Health Complaints Inventory (SHC; subscales musculoskeletal pain, pseudoneurology and gastrointestinal problems) and compared NF1 data to norms.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Compared to controls, significantly more persons with NF1 reported workplace bullying (13% versus 5%) and work as physically exhausting (74% versus 44%), whereas fewer reported work autonomy (64% versus 80%). Women with NF1 reported significantly more SHC than female norms (99% versus 86%). Men with NF1 reported significantly more pseudoneurology and gastrointestinal problems compared to male norms (76% versus 58%). SHC explained 9% of the variance in physical work experiences (\u03b2 = \u22120.47; 95% CI \u22120.76 to \u22120.19) and 8% of the variance in social work experiences (\u03b2 = 0.48; 95% CI 0.18\u20130.78).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Persons with NF1 experience more physical and social work problems, and both work domains were related to health complaints. Individualized assessment and information to co-workers and managers may represent ways to increase work participation among persons with NF1.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/occmed\/kqz134","type":"journal-article","created":{"date-parts":[[2019,9,28]],"date-time":"2019-09-28T02:57:18Z","timestamp":1569639438000},"source":"Crossref","is-referenced-by-count":4,"title":["Health complaints and work experiences among adults with neurofibromatosis 1"],"prefix":"10.1093","author":[{"given":"Krister W","family":"Fjermestad","sequence":"first","affiliation":[{"name":"Department of Psychology, University of Oslo, Oslo, Norway"},{"name":"Frambu Resource Centre for Rare Disorders, Siggerud, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,11,1]]},"reference":[{"key":"2019110106293387700_CIT0001","first-page":"297","article-title":"Neurofibromin in neurofibromatosis type 1\u2014mutations in NF1 gene as a cause of disease","volume":"18","author":"Abramowicz","year":"2014","journal-title":"Dev Period Med"},{"key":"2019110106293387700_CIT0002","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1055\/s-0036-1579766","article-title":"Neurofibromatosis: a review of NF1, NF2, and Schwannomatosis","volume":"5","author":"Kresak","year":"2016","journal-title":"J Pediatr Genet"},{"key":"2019110106293387700_CIT0003","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1542\/peds.2007-3204","article-title":"Neurofibromatosis type 1 revisited","volume":"123","author":"Williams","year":"2009","journal-title":"Pediatrics"},{"key":"2019110106293387700_CIT0004","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1542\/peds.105.3.608","article-title":"Use of the National Institutes of Health criteria for diagnosis of neurofibromatosis 1 in children","volume":"105","author":"DeBella","year":"2000","journal-title":"Pediatrics"},{"key":"2019110106293387700_CIT0005","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1007\/s10897-018-0229-5","article-title":"Health survey of adults with neurofibromatosis 1 compared to population study controls","volume":"27","author":"Fjermestad","year":"2018","journal-title":"J Genet Couns"},{"key":"2019110106293387700_CIT0006","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1159\/000187594","article-title":"Health-related quality of life in patients with neurofibromatosis type 1. 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