{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T22:44:33Z","timestamp":1778280273422,"version":"3.51.4"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,1,10]],"date-time":"2020-01-10T00:00:00Z","timestamp":1578614400000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Fujian Medical University Sailing Fund","award":["2016QH121"],"award-info":[{"award-number":["2016QH121"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>To explore the efficacy of postoperative antifungal treatment for preventing the recurrence of pulmonary cryptococcosis (PC) and occurrence of cryptococcal meningitis (CM), a retrospective study was conducted in 112 hospitalized PC patients with or without antifungal treatment following surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The treatment failure rate, PC recurrence rate, and CM incidence were compared. Additionally, the effectiveness of postoperative antifungal therapy was assessed by gathering and analyzing the published literature.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The failure rate (P\u2005=\u2005.054) and recurrence rate (P\u2005=\u2005.178) were similar in the 2 groups, but the incidence of CM was lower in the group that received postoperative antifungal treatment (P\u2005=\u2005.039).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This study did not show any difference in the PC recurrence rate or failure rate in the different treatment duration groups. Thus, a shorter antifungal treatment course of 2 months may be an optional treatment. In addition, upon review of the literature, no case of CM occurrence was reported among the 169 cases given postoperative antifungal treatment.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ofid\/ofaa004","type":"journal-article","created":{"date-parts":[[2020,1,10]],"date-time":"2020-01-10T08:16:18Z","timestamp":1578644178000},"source":"Crossref","is-referenced-by-count":7,"title":["Postoperative Antifungal Treatment of Pulmonary Cryptococcosis in Non-HIV-Infected and Non-Transplant-Recipient Patients: A Report of 110 Cases and Literature Review"],"prefix":"10.1093","volume":"7","author":[{"given":"Shuo","family":"Wei","sequence":"first","affiliation":[{"name":"Jinling Hospital Department of Respiratory Medicine, Southern Medical University (Guangzhou), Nanjing, China"},{"name":"Fujian Provincial Hospital, Fujian Medical University, Fuzhou, 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