{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T03:39:38Z","timestamp":1781753978969,"version":"3.54.5"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Harvard MIT Center for Regulatory Sciences"},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["U54-CA225088"],"award-info":[{"award-number":["U54-CA225088"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["T32-GM007753"],"award-info":[{"award-number":["T32-GM007753"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["U54-CA225088"],"award-info":[{"award-number":["U54-CA225088"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Proper disinfection using adequate disinfecting agents will be necessary for infection control strategies against coronavirus disease 2019 (COVID-19). However, limited guidance exists on effective surface disinfectants or best practices for their use against severe acute respiratory coronavirus 2. We outlined a process of fully characterizing over 350 products on the Environmental Protection Agency List N, including pH, method of delivery, indication for equipment sterilization, and purchase availability. We then developed a streamlined set of guidelines to help rapidly evaluate and select suitable disinfectants from List N, including practicality, efficacy, safety, and cost\/availability. This resource guides the evaluation of ideal disinfectants amidst practical considerations posed by the COVID-19 pandemic.<\/jats:p>","DOI":"10.1093\/ofid\/ofaa396","type":"journal-article","created":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T20:32:15Z","timestamp":1598905935000},"source":"Crossref","is-referenced-by-count":6,"title":["Considerations for the Selection and Use of Disinfectants Against SARS-CoV-2 in a Health Care Setting"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8585-1802","authenticated-orcid":false,"given":"Kevin","family":"Tyan","sequence":"first","affiliation":[{"name":"Greater Boston Pandemic Fabrication Team (PanFab) c\/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriane","family":"Levin","sequence":"additional","affiliation":[{"name":"Greater Boston Pandemic Fabrication Team (PanFab) c\/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Department of Dermatology, Brigham and Women\u2019s Hospital, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandra","family":"Avalos-Pacheco","sequence":"additional","affiliation":[{"name":"Greater Boston Pandemic Fabrication Team (PanFab) c\/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Dana-Farber Cancer Institute, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Plana","sequence":"additional","affiliation":[{"name":"Greater Boston Pandemic Fabrication Team (PanFab) c\/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Harvard-MIT Division of Health Sciences & Technology, Cambridge, Massachusetts, USA"},{"name":"Harvard Ludwig Cancer Research Center and Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleanor A","family":"Rand","sequence":"additional","affiliation":[{"name":"Greater Boston Pandemic Fabrication Team (PanFab) c\/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Harvard University Department of Systems Biology, Cambridge, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Yang","sequence":"additional","affiliation":[{"name":"Greater Boston Pandemic Fabrication Team (PanFab) c\/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura E","family":"Maliszewski","sequence":"additional","affiliation":[{"name":"Greater Boston Pandemic Fabrication Team (PanFab) c\/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Harvard Program in Therapeutic Science, Cambridge, Massachusetts, USA"},{"name":"Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lily A","family":"Chylek","sequence":"additional","affiliation":[{"name":"Greater Boston Pandemic Fabrication Team (PanFab) c\/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyla","family":"Atta","sequence":"additional","affiliation":[{"name":"Greater Boston Pandemic Fabrication Team (PanFab) c\/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A","family":"Tye","sequence":"additional","affiliation":[{"name":"Greater Boston Pandemic Fabrication Team (PanFab) c\/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Harvard University Graduate School of Arts and Sciences, Cambridge, Massachusetts, USA"},{"name":"Massachusetts General Hospital Center for Systems Biology, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary M","family":"Carmack","sequence":"additional","affiliation":[{"name":"Greater Boston Pandemic Fabrication Team (PanFab) c\/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Computational Health Informatics Program, Boston Children\u2019s Hospital, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N Synclaire","family":"Oglesby","sequence":"additional","affiliation":[{"name":"Greater Boston Pandemic Fabrication Team (PanFab) c\/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Harvard Program in Therapeutic Science, Cambridge, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Burgin","sequence":"additional","affiliation":[{"name":"Greater Boston Pandemic Fabrication Team (PanFab) c\/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Brigham and Women\u2019s Hospital, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherry H","family":"Yu","sequence":"additional","affiliation":[{"name":"Greater Boston Pandemic Fabrication Team (PanFab) c\/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole R","family":"LeBoeuf","sequence":"additional","affiliation":[{"name":"Greater Boston Pandemic Fabrication Team (PanFab) c\/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Department of Dermatology, Brigham and Women\u2019s Hospital, Boston, Massachusetts, USA"},{"name":"Dana-Farber Cancer Institute, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline M","family":"Kemp","sequence":"additional","affiliation":[{"name":"Greater Boston Pandemic Fabrication Team (PanFab) c\/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Department of Dermatology, Brigham and Women\u2019s Hospital, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,8,31]]},"reference":[{"key":"2020092114342347500_CIT0001","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1056\/NEJMc2004973","article-title":"Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1","volume":"382","author":"van Doremalen","year":"2020","journal-title":"N Engl J Med"},{"key":"2020092114342347500_CIT0002","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.jhin.2020.01.022","article-title":"Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents","volume":"104","author":"Kampf","year":"2020","journal-title":"J Hosp Infect"},{"key":"2020092114342347500_CIT0003","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1001\/jama.2020.3227","article-title":"Air, surface environmental, and personal protective equipment contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a symptomatic patient","volume":"323","author":"Ong","year":"2020","journal-title":"JAMA"},{"key":"2020092114342347500_CIT0004","doi-asserted-by":"crossref","first-page":"12732","DOI":"10.1038\/s41598-020-69286-3","article-title":"Aerosol and surface contamination of SARS-CoV-2 observed in quarantine and isolation care","volume":"10","author":"Santarpia","year":"2020","journal-title":"Sci Rep"},{"key":"2020092114342347500_CIT0005","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/s41586-020-2271-3","article-title":"Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals","volume":"582","author":"Liu","year":"2020","journal-title":"Nature"},{"key":"2020092114342347500_CIT0006","doi-asserted-by":"crossref","DOI":"10.7326\/M20-2237","article-title":"Investing in our first line of defense: environmental services workers","author":"Tyan","year":"2020","journal-title":"Ann Intern Med"},{"key":"2020092114342347500_CIT0007","author":"List N: disinfectants for use against SARS-CoV-2.","year":"2020"},{"key":"2020092114342347500_CIT0008","author":"Tullo","year":"2020"},{"key":"2020092114342347500_CIT0009","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1086\/676877","article-title":"Selection of the ideal disinfectant","volume":"35","author":"Rutala","year":"2014","journal-title":"Infect Control Hosp Epidemiol"},{"key":"2020092114342347500_CIT0010","doi-asserted-by":"crossref","first-page":"e73","DOI":"10.1056\/NEJMc2009432","article-title":"Opening up new supply chains","volume":"382","author":"Zeidel","year":"2020","journal-title":"N Engl J Med"},{"key":"2020092114342347500_CIT0011","author":"Rutala","year":"2020"},{"key":"2020092114342347500_CIT0012","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1017\/ice.2018.323","article-title":"A novel color additive for bleach wipes indicates surface coverage and contact time to improve thoroughness of cleaning","volume":"40","author":"Tyan","year":"2019","journal-title":"Infect Control Hosp Epidemiol"},{"key":"2020092114342347500_CIT0013","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1017\/ice.2017.288","article-title":"Surface disinfection: treatment time (wipes and sprays) versus contact time (liquids)","volume":"39","author":"Rutala","year":"2018","journal-title":"Infect Control Hosp Epidemiol"},{"key":"2020092114342347500_CIT0014","first-page":"175","article-title":"Factors in the selection of surface disinfectants for use in a laboratory animal setting","volume":"55","author":"Campagna","year":"2016","journal-title":"J Am Assoc Lab Anim Sci"},{"key":"2020092114342347500_CIT0015","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1111\/j.1556-4029.2011.01752.x","article-title":"The effects of corrosive substances on human bone, teeth, hair, nails, and soft tissue","volume":"56","author":"Hartnett","year":"2011","journal-title":"J Forensic Sci"},{"key":"2020092114342347500_CIT0016","doi-asserted-by":"crossref","first-page":"1700237","DOI":"10.1183\/13993003.00237-2017","article-title":"Occupational exposure to disinfectants and asthma control in US nurses","volume":"50","author":"Dumas","year":"2017","journal-title":"Eur Respir J"},{"key":"2020092114342347500_CIT0017","doi-asserted-by":"crossref","first-page":"e1913563","DOI":"10.1001\/jamanetworkopen.2019.13563","article-title":"Association of occupational exposure to disinfectants with incidence of chronic obstructive pulmonary disease among US female nurses","volume":"2","author":"Dumas","year":"2019","journal-title":"JAMA Netw Open"},{"key":"2020092114342347500_CIT0018","doi-asserted-by":"crossref","first-page":"e69","DOI":"10.1016\/j.ajic.2017.04.290","article-title":"Effectiveness of cleaning-disinfection wipes and sprays against multidrug-resistant outbreak strains","volume":"45","author":"Kenters","year":"2017","journal-title":"Am J Infect Control"},{"key":"2020092114342347500_CIT0019","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1016\/j.ajic.2016.05.028","article-title":"Disinfectant sprays versus wipes: applications in behavioral health","volume":"44","author":"Wiemken","year":"2016","journal-title":"Am J Infect Control"},{"key":"2020092114342347500_CIT0020","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1017\/ice.2015.299","article-title":"Quaternary ammonium disinfectant issues encountered in an environmental services department","volume":"37","author":"Boyce","year":"2016","journal-title":"Infect Control Hosp Epidemiol"},{"key":"2020092114342347500_CIT0021","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.jhin.2018.09.012","article-title":"Novel colour additive for bleach disinfectant wipes reduces corrosive damage on stainless steel","volume":"103","author":"Tyan","year":"2019","journal-title":"J Hosp Infect"},{"key":"2020092114342347500_CIT0022","author":"Terlep","year":"2020"}],"container-title":["Open Forum Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ofid\/advance-article-pdf\/doi\/10.1093\/ofid\/ofaa396\/33702093\/ofaa396.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ofid\/article-pdf\/7\/9\/ofaa396\/33777829\/ofaa396.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ofid\/article-pdf\/7\/9\/ofaa396\/33777829\/ofaa396.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T19:08:22Z","timestamp":1600715302000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ofid\/article\/doi\/10.1093\/ofid\/ofaa396\/5899802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,31]]},"references-count":22,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ofid\/ofaa396","relation":{},"ISSN":["2328-8957"],"issn-type":[{"value":"2328-8957","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,9]]},"published":{"date-parts":[[2020,8,31]]},"article-number":"ofaa396"}}