{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T15:05:44Z","timestamp":1790867144739,"version":"4.1.0"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,11,27]],"date-time":"2020-11-27T00:00:00Z","timestamp":1606435200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Peritoneal dialysis (PD)\u2013associated peritonitis constitutes a major complication associated with the procedure. PD-associated peritonitis caused by nontuberculous mycobacteria, usually as a result of an infection related to the PD catheter, has been reported in adults and is associated with significant complications and poor outcome. The management of PD-associated peritonitis caused by Mycobacterium abscessus is particularly challenging because this species is resistant to many antimicrobials commonly used to treat mycobacterial species. We present here the second reported case of PD-associated peritonitis caused by M. abscessus in children. Our patient was a 9-year-old boy with end-stage renal disease (ESRD) who presented with suspected peritonitis, and his PD fluid cultures eventually grew M. abscessus. The patient received a 3-week course of triple therapy with clarithromycin, amikacin, and meropenem in addition to PD catheter removal. The infection completely resolved even though a susceptibility report at the end of treatment revealed that the isolate was resistant to clarithromycin and had decreased susceptibility to carbapenems. Our observations suggest that PD catheter removal is important in PD-associated peritonitis caused by M. abscessus in children and that more studies are needed to define the optimal length of treatment.<\/jats:p>","DOI":"10.1093\/ofid\/ofaa579","type":"journal-article","created":{"date-parts":[[2020,11,27]],"date-time":"2020-11-27T00:16:44Z","timestamp":1606436204000},"source":"Crossref","is-referenced-by-count":11,"title":["Peritoneal Dialysis\u2013Associated Peritonitis Caused by <i>Mycobacterium abscessus<\/i> in Children\u2014A Case Report"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9591-8719","authenticated-orcid":false,"given":"Omar","family":"Imam","sequence":"first","affiliation":[{"name":"Division of Pediatric Infectious Diseases, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Al-Zubaidi","sequence":"additional","affiliation":[{"name":"Division of Pediatric Infectious Diseases, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Janahi","sequence":"additional","affiliation":[{"name":"Division of Pediatric Infectious Diseases, Doha, Qatar"},{"name":"Department of Infection Prevention and Control, Sidra Medicine, Doha, Qatar"},{"name":"Weill Cornell Medical College in Qatar, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abubakr","family":"Imam","sequence":"additional","affiliation":[{"name":"Division of Pediatric Nephrology, Doha, Qatar"},{"name":"Department of Infection Prevention and Control, Sidra Medicine, Doha, Qatar"},{"name":"Weill Cornell Medical College in Qatar, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bassil","family":"Leghrouz","sequence":"additional","affiliation":[{"name":"Division of Pediatric Nephrology, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Dobson","sequence":"additional","affiliation":[{"name":"Department of Infection Prevention and Control, Sidra Medicine, Doha, Qatar"},{"name":"Weill Cornell Medical College in Qatar, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sathyavathi","family":"Sundararaju","sequence":"additional","affiliation":[{"name":"Division of Microbiology, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kin Ming","family":"Tsui","sequence":"additional","affiliation":[{"name":"Division of Microbiology, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Rubayet","family":"Hasan","sequence":"additional","affiliation":[{"name":"Division of Microbiology, Doha, Qatar"},{"name":"Department of Infection Prevention and Control, Sidra Medicine, Doha, Qatar"},{"name":"Weill Cornell Medical College in Qatar, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andres","family":"Perez-Lopez","sequence":"additional","affiliation":[{"name":"Division of Microbiology, Doha, Qatar"},{"name":"Department of Infection Prevention and Control, Sidra Medicine, Doha, Qatar"},{"name":"Weill Cornell Medical College in Qatar, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,11,27]]},"reference":[{"key":"2021012918355830800_CIT0001","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1186\/s12879-020-04966-z","article-title":"Unusual accumulation of a wide array of antimicrobial resistance mechanisms in a patient with cytomegalovirus-associated hemophagocytic lymphohistiocytosis: a case report","volume":"20","author":"Hasan","year":"2020","journal-title":"BMC Infect Dis"},{"key":"2021012918355830800_CIT0002","first-page":"D517","article-title":"CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database","volume":"48","author":"Alcock","year":"2020","journal-title":"Nucleic Acids Res"},{"key":"2021012918355830800_CIT0003","doi-asserted-by":"crossref","first-page":"2640","DOI":"10.1093\/jac\/dks261","article-title":"Identification of acquired antimicrobial resistance genes","volume":"67","author":"Zankari","year":"2012","journal-title":"J Antimicrob Chemother"},{"key":"2021012918355830800_CIT0004","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1089\/cmb.2012.0021","article-title":"SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing","volume":"19","author":"Bankevich","year":"2012","journal-title":"J Comput Biol"},{"key":"2021012918355830800_CIT0005","doi-asserted-by":"crossref","first-page":"e01204","DOI":"10.1128\/AAC.01204-18","article-title":"Whole-genome sequencing for predicting clarithromycin resistance in Mycobacterium abscessus","volume":"63","author":"Lipworth","year":"2018","journal-title":"Antimicrob Agents Chemother"},{"key":"2021012918355830800_CIT0006","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.3201\/2109.141634","article-title":"Mycobacterium abscessus complex infections in humans","volume":"21","author":"Lee","year":"2015","journal-title":"Emerg Infect Dis"},{"key":"2021012918355830800_CIT0007","article-title":"Clofazimine in Mycobacterium abscessus peritonitis: a pediatric case report","author":"Pinapala","year":"","journal-title":"Perit Dial Int"},{"key":"2021012918355830800_CIT0008","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1053\/j.ajkd.2014.02.025","article-title":"Peritoneal dialysis-related peritonitis: towards improving evidence, practices, and outcomes","volume":"64","author":"Cho","year":"2014","journal-title":"Am J Kidney Dis"},{"key":"2021012918355830800_CIT0009","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1093\/ndt\/gfr504","article-title":"Peritoneal dialysis-associated nontuberculous Mycobacterium peritonitis: a systematic review of reported cases","volume":"27","author":"Song","year":"2012","journal-title":"Nephrol Dial Transplant"},{"key":"2021012918355830800_CIT0010","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1159\/000485716","article-title":"The role of non-tuberculous mycobacteria in peritoneal dialysis-related infections: a literature review","volume":"196","author":"Washida","year":"2018","journal-title":"Contrib Nephrol"},{"key":"2021012918355830800_CIT0011","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1186\/s12882-018-1148-2","article-title":"Peritoneal dialysis-associated infection caused by Mycobacterium abscessus: a case report","volume":"19","author":"Yoshimura","year":"2018","journal-title":"BMC Nephrol"},{"key":"2021012918355830800_CIT0012","doi-asserted-by":"crossref","first-page":"267","DOI":"10.3747\/pdi.2011.00184","article-title":"Atypical mycobacterial exit-site infection and peritonitis in peritoneal dialysis patients on prophylactic exit-site gentamicin cream","volume":"33","author":"Lo","year":"2013","journal-title":"Perit Dial Int"},{"key":"2021012918355830800_CIT0013","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.3201\/eid0912.020774","article-title":"Mycobacterium abscessus and children with cystic fibrosis","volume":"9","author":"Sermet-Gaudelus","year":"2003","journal-title":"Emerg Infect Dis"},{"key":"2021012918355830800_CIT0014","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s00467-008-1113-6","article-title":"Dialysis-associated peritonitis in children","volume":"25","author":"Chadha","year":"2010","journal-title":"Pediatr Nephrol"},{"key":"2021012918355830800_CIT0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijid.2017.07.022","article-title":"Rapidly growing Mycobacterium infections after cosmetic surgery in medical tourists: the Bronx experience and a review of the literature","volume":"63","author":"Cusumano","year":"2017","journal-title":"Int J Infect Dis"},{"key":"2021012918355830800_CIT0016","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1128\/AAC.01275-08","article-title":"A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae","volume":"53","author":"Nash","year":"2009","journal-title":"Antimicrob Agents Chemother"}],"container-title":["Open Forum Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ofid\/advance-article-pdf\/doi\/10.1093\/ofid\/ofaa579\/34556241\/ofaa579.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ofid\/article-pdf\/8\/1\/ofaa579\/36149746\/ofaa579.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ofid\/article-pdf\/8\/1\/ofaa579\/36149746\/ofaa579.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,29]],"date-time":"2021-01-29T18:36:11Z","timestamp":1611945371000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ofid\/article\/doi\/10.1093\/ofid\/ofaa579\/6006998"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,27]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ofid\/ofaa579","relation":{},"ISSN":["2328-8957"],"issn-type":[{"value":"2328-8957","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,1]]},"published":{"date-parts":[[2020,11,27]]},"article-number":"ofaa579"}}