{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T01:24:10Z","timestamp":1769563450125,"version":"3.49.0"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T00:00:00Z","timestamp":1611360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["Y1-AI-5072"],"award-info":[{"award-number":["Y1-AI-5072"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HU0001190002"],"award-info":[{"award-number":["HU0001190002"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Coronavirus disease 2019 (COVID-19) presents a unique challenge to United States Navy hospital ships. The aim of this study was to determine the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among US Navy personnel deployed on the USNS COMFORT to augment the inpatient health care capacity in New York City.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This was a cross-sectional study conducted on USNS COMFORT crewmembers returning to Norfolk, Virginia, following deployment. Participants completed an electronic questionnaire and provided a serum sample at Day 14 post-deployment. Polymerase chain reaction (PCR) results from testing of symptomatic crewmembers during deployment and Day 0 and Day 14 post-deployment screening swabs conducted on all crewmembers, per military order, were abstracted. SARS-CoV-2 infection was defined as a positive SARS-CoV-2 spike glycoprotein immunoglobulin G antibody or PCR result.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of the ship\u2019s total complement of 1200 crewmembers, 450 were enrolled: 432 (96.0%) completed the questionnaire and provided a serum sample. The median age of participants (interquartile range) was 30 (24\u201339) years, 50.8% were female, 58.6% were White, and 14.0% were Black; 80.1% had a clinical role during deployment. The cumulative prevalence of SARS-CoV-2 infection was 3.01% (13\/432; 95% CI, 1.61%\u20135.09%). Twelve of 13 infections occurred in health care providers, and 8 of 13 were asymptomatic. The antibody profile of infected crewmembers varied by suspected timing of infection.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>We observed a low prevalence of SARS-CoV-2 infection among USNS COMFORT crewmembers despite the inherent risk of a shipboard deployment to an area with high rates of community transmission. Our findings suggest that early infection control measures mitigated the spread of SARS-CoV-2 among crewmembers.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ofid\/ofaa654","type":"journal-article","created":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T23:36:54Z","timestamp":1611445014000},"source":"Crossref","is-referenced-by-count":17,"title":["SARS-CoV-2 Infections and Serologic Responses Among Military Personnel Deployed on the USNS COMFORT to New York City During the COVID-19 Pandemic"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9361-2991","authenticated-orcid":false,"given":"Tahaniyat","family":"Lalani","sequence":"first","affiliation":[{"name":"Infectious Disease Clinical Research Program, Uniformed Services University, Bethesda, Maryland, USA"},{"name":"Henry M Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA"},{"name":"Naval Medical Center Portsmouth, Portsmouth, Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tida K","family":"Lee","sequence":"additional","affiliation":[{"name":"Naval Medical Center Portsmouth, Portsmouth, Virginia, USA"},{"name":"Department of Medicine, Uniformed Services University, Bethesda, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric D","family":"Laing","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Ritter","sequence":"additional","affiliation":[{"name":"Naval Medical Center Portsmouth, Portsmouth, Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Cooper","sequence":"additional","affiliation":[{"name":"Naval Medical Center Portsmouth, Portsmouth, Virginia, 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University, Bethesda, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Samuels","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huy","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Naval Medical Center Portsmouth, Portsmouth, Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher C","family":"Broder","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nusrat","family":"Epsi","sequence":"additional","affiliation":[{"name":"Infectious Disease Clinical Research Program, Uniformed Services University, Bethesda, Maryland, USA"},{"name":"Henry M Jackson Foundation for the 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