{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T19:21:27Z","timestamp":1773343287874,"version":"3.50.1"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T00:00:00Z","timestamp":1629331200000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002808","name":"Carlsberg Foundation","doi-asserted-by":"publisher","award":["CF20-476 0045"],"award-info":[{"award-number":["CF20-476 0045"]}],"id":[{"id":"10.13039\/501100002808","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Foundation","doi-asserted-by":"publisher","award":["NFF205A0063505"],"award-info":[{"award-number":["NFF205A0063505"]}],"id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Foundation","doi-asserted-by":"publisher","award":["NNF20SA0064201"],"award-info":[{"award-number":["NNF20SA0064201"]}],"id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Health care workers are at a higher risk of getting infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) than the general population. Knowledge about medical students\u2019 exposure to SARS-CoV-2 is lacking. Thus, we measured the prevalence of SARS-CoV-2 antibodies in a cohort of Danish medical students.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We invited all medical students at the University of Copenhagen (UCPH) to participate. Students underwent venous blood sampling and a questionnaire about work-life behaviors possibly associated with SARS-CoV-2 exposure and coronavirus disease 2019 (COVID-19) symptoms. Samples were analyzed for total immunoglobulin G (IgG) antibodies against SARS-CoV-2, and seropositive samples were screened for IgG, immunoglobulin M, and immunoglobulin A antibodies. We determined associations between seropositivity and clinical and social activities and self-reported symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Between October 19 and 26, 1120 students participated in the questionnaire and 1096 were included. Of all included, 379 (34.58%) were seropositive. Seropositivity was associated with attendance at 2 parties at UCPH, on February 29 and March 6, 2020 (odds ratio [OR], 5.96; 95% CI, 4.34\u20138.24; P\u2005&amp;lt;\u2005.001). Four hundred sixty-one students (42.06%) worked with COVID-19 patients, which was significantly associated with seropositivity (OR, 1.38; 95% CI, 1.03\u20131.85; P\u2005=\u2005.033). The symptom most associated with seropositivity was loss of smell and\/or taste (n\u2005=\u2005183 of all, 31.35%; OR, 24.48; 95% CI, 15.49\u201340.60; P\u2005&amp;lt;\u2005.001). Bachelor\u2019s students were significantly more likely to be seropositive than Master\u2019s students (42.28% vs 16.87%; P\u2005&amp;lt;\u2005.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Medical students have the highest reported seropositivity in the Danish health care system. In this cohort of students at UCPH, seropositivity was associated with social behavior markers and, to a lesser extent, with self-reported contact with SARS-CoV-2-infected patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ofid\/ofab273","type":"journal-article","created":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T00:39:02Z","timestamp":1629333542000},"source":"Crossref","is-referenced-by-count":9,"title":["Anti-SARS-CoV-2 Seropositivity Among Medical Students in Copenhagen"],"prefix":"10.1093","volume":"8","author":[{"given":"Johannes R","family":"Madsen","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Herlev-Gentofte Hospital, Copenhagen,Denmark"},{"name":"Laboratory of Molecular Medicine, Department of Clinical Immunology, Section 7631, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob P S","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Herlev-Gentofte Hospital, Copenhagen,Denmark"},{"name":"Laboratory of Molecular Medicine, Department of Clinical Immunology, Section 7631, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamille","family":"Fogh","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Herlev-Gentofte Hospital, Copenhagen,Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilie B","family":"Hansen","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Medicine, Department of Clinical Immunology, Section 7631, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pernille B","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Herlev-Gentofte Hospital, Copenhagen,Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theis","family":"Lange","sequence":"additional","affiliation":[{"name":"Section of Biostatistics, Department of Public Health, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rasmus B","family":"Hasselbalch","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Herlev-Gentofte Hospital, Copenhagen,Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Garred","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Medicine, Department of Clinical Immunology, Section 7631, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kasper","family":"Iversen","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Herlev-Gentofte Hospital, Copenhagen,Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,8,19]]},"reference":[{"key":"2021081904311760700_CIT0001","author":"World Health Organization.","year":"2020"},{"key":"2021081904311760700_CIT0002","year":"2021"},{"key":"2021081904311760700_CIT0003","author":"Copenhagen."},{"key":"2021081904311760700_CIT0004","doi-asserted-by":"crossref","first-page":"e79","DOI":"10.1016\/S0140-6736(20)30923-5","article-title":"Medical students for health-care staff shortages during the COVID-19 pandemic","volume":"395","author":"Rasmussen","year":"2020","journal-title":"Lancet"},{"key":"2021081904311760700_CIT0005","author":"The Union of Danish Medicial Students employment agency (FADL\u2019s vagtbureau). vagtbureau 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