{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T18:14:48Z","timestamp":1792692888252,"version":"4.5.0"},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Studies performed during the 1940s\u20131960s continue to serve as the foundation of the epidemiology of histoplasmosis given that many knowledge gaps persist regarding its geographic distribution, prevalence, and burden in the United States. We explore 3 long-standing, frequently cited, and somewhat incomplete epidemiologic beliefs about histoplasmosis: (1) histoplasmosis is the most common endemic mycosis in the United States, (2) histoplasmosis is endemic to the Ohio and Mississippi River Valleys, and (3) histoplasmosis is associated with bird or bat droppings. We also summarize recent insights about the clinical spectrum of histoplasmosis and changes in underlying conditions associated with the severe forms. Continuing to identify prevention opportunities will require better epidemiologic data, better diagnostic testing, and greater awareness about this neglected disease among health care providers, public health professionals, and the general public.<\/jats:p>","DOI":"10.1093\/ofid\/ofab306","type":"journal-article","created":{"date-parts":[[2021,6,10]],"date-time":"2021-06-10T14:30:24Z","timestamp":1623335424000},"source":"Crossref","is-referenced-by-count":26,"title":["Revising Conventional Wisdom About Histoplasmosis in the United States"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0458-2493","authenticated-orcid":false,"given":"Kaitlin","family":"Benedict","sequence":"first","affiliation":[{"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuru","family":"Toda","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan R","family":"Jackson","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,6,10]]},"reference":[{"key":"2021102308450874400_CIT0001","doi-asserted-by":"crossref","first-page":"e2034890","DOI":"10.1001\/jamanetworkopen.2020.34890","article-title":"Allocation of National Institutes of Health funding by disease category in 2008 and 2019","volume":"4","author":"Ballreich","year":"2021","journal-title":"JAMA Netw Open"},{"key":"2021102308450874400_CIT0002","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1056\/NEJM195702072560605","article-title":"The history of histoplasmosis, 1906 to 1956","volume":"256","author":"Baum","year":"1957","journal-title":"N Engl J Med"},{"key":"2021102308450874400_CIT0003","first-page":"144","article-title":"Physical examination at induction","author":"Long","year":"1943"},{"key":"2021102308450874400_CIT0004","first-page":"Suppl):1","article-title":"An atlas of sensitivity to tuberculin, PPD-B, and histoplasmin in the United States","volume":"99","author":"Edwards","year":"1969","journal-title":"Am Rev Respir Dis"},{"key":"2021102308450874400_CIT0005","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1378\/chest.29.6.649","article-title":"Geographic variation in the prevalence of histoplasmin sensitivity","volume":"29","author":"Manos","year":"1956","journal-title":"Dis Chest"},{"key":"2021102308450874400_CIT0006","doi-asserted-by":"crossref","first-page":"475","DOI":"10.2307\/4585617","article-title":"Geographic differences in sensitivity to histoplasmin among student nurses","volume":"61","author":"Palmer","year":"1946","journal-title":"Public Health Rep"},{"key":"2021102308450874400_CIT0007","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/0021-9681(57)90117-0","article-title":"Epidemic histoplasmosis","volume":"5","author":"Lehan","year":"1957","journal-title":"J Chronic Dis"},{"key":"2021102308450874400_CIT0008","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1053\/srin.2001.24241","article-title":"The epidemiology of histoplasmosis: a review","volume":"16","author":"Cano","year":"2001","journal-title":"Semin Respir Infect"},{"key":"2021102308450874400_CIT0009","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1164\/rccm.201906-1185ST","article-title":"Microbiological laboratory testing in the diagnosis of fungal infections in pulmonary and critical care practice. 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