{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T16:19:52Z","timestamp":1777306792355,"version":"3.51.4"},"reference-count":0,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T00:00:00Z","timestamp":1636070400000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Uninsured people who use drugs (PWUD) require extended parenteral antibiotic therapy when diagnosed with complex infections such as osteomyelitis. They are ineligible to enroll in our self-administered outpatient antimicrobial therapy (S-OPAT) program and instead sent to a skilled nursing facility (SNF). We aim to retrospectively assess clinical outcomes of PWUD discharged from our safety net hospital to complete OPAT in a SNF.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Using our hospital electronic medical record, PWUD and discharged to SNF for extended antibiotic therapy were identified for the study period 1\/1\/17 -4\/30\/18. Demographics, drug use, discharge diagnosis, antibiotic therapy, discharge disposition from SNF (AMA, early non-AMA, completed), 30-day emergency department (ED) utilization, and 30-day readmission were collected for the study cohort. ED-utilization and 30-day readmission rates were analyzed by disposition group.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n While the majority of patients completed treatment (83), a sizeable number left AMA (26) or early non-AMA (20) Patients who left early, AMA or non-AMA, had increased rates of 30-day readmission or ED-utilization (p=0.01), increased rates of 30-day readmission alone (p=0.01), but not ED-utilization alone (p=0.43) compared to patients who completed treatment.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n In our cohort, many PWUD discharged to SNF to receive parenteral antibiotics do not complete treatment. These patients are observed to have increased healthcare utilization compared to patients completing therapy.<\/jats:p>\n <\/jats:sec>","DOI":"10.1093\/ofid\/ofab540","type":"journal-article","created":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T14:02:46Z","timestamp":1636120966000},"source":"Crossref","is-referenced-by-count":7,"title":["Healthcare Utilization Patterns for Patients with a History of Substance Use Requiring OPAT"],"prefix":"10.1093","author":[{"given":"Bilal","family":"Ashraf","sequence":"first","affiliation":[{"name":"UT Southwestern Department of Internal Medicine and Pediatrics, Dallas, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Hoff","sequence":"additional","affiliation":[{"name":"UT Southwestern Department of Internal Medicine, Dallas, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L Steven","family":"Brown","sequence":"additional","affiliation":[{"name":"Parkland Health and Hospital System, Dallas, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jillian","family":"Smartt","sequence":"additional","affiliation":[{"name":"Parkland Health and Hospital System Center of Innovation and Value, Dallas, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheryl","family":"Mathew","sequence":"additional","affiliation":[{"name":"Parkland Health and Hospital System Center of Innovation and Value, Dallas, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cylaina","family":"Bird","sequence":"additional","affiliation":[{"name":"UT Southwestern Department of Internal Medicine, Dallas, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan","family":"Collins","sequence":"additional","affiliation":[{"name":"Parkland Health and Hospital System, Dallas, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Johnson","sequence":"additional","affiliation":[{"name":"UT Southwestern Department of Internal Medicine, Dallas, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kapila","family":"Marambage","sequence":"additional","affiliation":[{"name":"UT Southwestern Department of Psychiatry, Dallas, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kavita","family":"Bhavan","sequence":"additional","affiliation":[{"name":"Parkland Health and Hospital System Center of Innovation and Value, Dallas, Texas, United States"},{"name":"UT Southwestern Department of Internal Medicine, Division of Infectious Diseases, Dallas, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,11,5]]},"container-title":["Open Forum Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ofid\/advance-article-pdf\/doi\/10.1093\/ofid\/ofab540\/41090498\/ofab540.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ofid\/advance-article-pdf\/doi\/10.1093\/ofid\/ofab540\/41090498\/ofab540.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T14:02:47Z","timestamp":1636120967000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ofid\/advance-article\/doi\/10.1093\/ofid\/ofab540\/6421693"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,5]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/ofid\/ofab540","relation":{},"ISSN":["2328-8957"],"issn-type":[{"value":"2328-8957","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,5]]},"article-number":"ofab540"}}