{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:09:43Z","timestamp":1787724583472,"version":"build-2784847793"},"reference-count":77,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T00:00:00Z","timestamp":1664496000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,10,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Mycobacterium genavense infection is rare and can occur in immunocompromised patients without human immunodeficiency virus (HIV).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We describe 2 cases of M genavense infection in solid organ transplant (SOT) recipients, and we performed a literature review of immunocompromised patients without HIV.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Fifty-two cases are reported. Predisposing factors were receipt of SOT (40.4%) and autoimmune disease (36.5%). Infection was disseminated in 86.5% of cases. Organs involved were lymph nodes (72.3%), gastrointestinal tract (56.5%), lung (35.5%), and bone marrow (28.8%). Most patients were treated with at least 3 antimycobacterial agents (98%), with a clinical cure achieved in 54.9%. In multivariate analysis, lack for cure was associated with age of the time infection (odds ratio [OR], 15.81 [95% confidence interval {CI}, 2.92\u2013152.93]; P = .011) and positive bone marrow culture (OR, 1.05 [95% CI, 1.01\u20131.12]; P = .042).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Mycobacterium genavense infection is a rare and generally disseminated disease with a poor prognosis. Optimal treatment regimen and its duration remain to be defined.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ofid\/ofac498","type":"journal-article","created":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T20:15:49Z","timestamp":1664568949000},"source":"Crossref","is-referenced-by-count":21,"title":["<i>Mycobacterium genavense<\/i> Infections in Immunocompromised Patients Without HIV: Case Series of Solid Organ Transplant Patients and Literature Review"],"prefix":"10.1093","volume":"9","author":[{"given":"Aur\u00e9lie","family":"Baldolli","sequence":"first","affiliation":[{"name":"CHU de Caen, Infectious Diseases Department, Avenue de la C\u00f4te de Nacre , Caen, F-14000 , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Chocron","sequence":"additional","affiliation":[{"name":"Emergency department, European Georges Pompidou Hospital (AP-HP) , 75015, Paris , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie","family":"Darg\u00e8re","sequence":"additional","affiliation":[{"name":"CHU de Caen, Infectious Diseases Department, Avenue de la C\u00f4te de Nacre , Caen, F-14000 , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jocelyn","family":"Michon","sequence":"additional","affiliation":[{"name":"CHU de Caen, Infectious Diseases Department, Avenue de la C\u00f4te de Nacre , Caen, F-14000 , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Daurel","sequence":"additional","affiliation":[{"name":"CHU de Caen, Microbiology Department , Avenue de la C\u00f4te de Nacre , Caen, F-14000 , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ang\u00e9lique","family":"Thuillier-Lecouf","sequence":"additional","affiliation":[{"name":"CHU de Caen, Nephrology Department , Avenue de la C\u00f4te de Nacre , Caen, F-14000 , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renaud","family":"Verdon","sequence":"additional","affiliation":[{"name":"CHU de Caen, Infectious Diseases Department, Avenue de la C\u00f4te de Nacre , Caen, F-14000 , France"},{"name":"INSERM U1311 DynaMicURe, Normandy University, UNICAEN, UNIROUEN , 14033 Caen , France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,9,30]]},"reference":[{"key":"2022102108581306800_ofac498-B1","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/0140-6736(92)90397-L","article-title":"Disseminated Mycobacterium genavense infection in patients with AIDS","volume":"340","author":"B\u00f6ttger","year":"1992","journal-title":"Lancet"},{"key":"2022102108581306800_ofac498-B2","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1080\/00365549950161907","article-title":"Generalized Mycobacterium genavense infection in HIV-infected patients: detection of the 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