{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:11:27Z","timestamp":1753877487566,"version":"3.41.2"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T00:00:00Z","timestamp":1664236800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,10,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Reported adverse reactions to the mRNA-1273 vaccine (Spikevax, Moderna Inc) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) range from mild, local delayed cutaneous reactions to rarer, more serious reactions such as myocarditis. Here, we describe the presentation and successful treatment of delayed, localized necrotizing inflammatory myositis following a third dose of the mRNA-1273 SARS-CoV-2 vaccine. To our knowledge, this is the first report of biopsy-confirmed, delayed inflammatory myositis after administration of an mRNA-1273 SARS-CoV-2 vaccine booster.<\/jats:p>","DOI":"10.1093\/ofid\/ofac499","type":"journal-article","created":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T16:59:37Z","timestamp":1664297977000},"source":"Crossref","is-referenced-by-count":2,"title":["Successful Treatment of Delayed Localized Necrotizing Inflammatory Myositis After Severe Acute Respiratory Syndrome Coronavirus 2 mRNA-1273 Vaccine: A Case Report"],"prefix":"10.1093","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3847-360X","authenticated-orcid":false,"given":"Jennifer Chen","family":"Li","sequence":"first","affiliation":[{"name":"Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital , Boston, Massachusetts , USA"},{"name":"Harvard Medical School , Boston, Massachusetts , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Siglin","sequence":"additional","affiliation":[{"name":"Harvard Medical School , Boston, Massachusetts , USA"},{"name":"Department of Medicine, Massachusetts General Hospital , Boston, Massachusetts , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael S","family":"Marshall","sequence":"additional","affiliation":[{"name":"Harvard Medical School , Boston, Massachusetts , USA"},{"name":"Department of Pathology, Massachusetts General Hospital , Boston, Massachusetts , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anat","family":"Stemmer-Rachamimov","sequence":"additional","affiliation":[{"name":"Harvard Medical School , Boston, Massachusetts , USA"},{"name":"Department of Pathology, Massachusetts General Hospital , Boston, Massachusetts , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0462-4596","authenticated-orcid":false,"given":"Seth M","family":"Bloom","sequence":"additional","affiliation":[{"name":"Harvard Medical School , Boston, Massachusetts , USA"},{"name":"Division of Infectious Diseases, Massachusetts General Hospital , Boston, Massachusetts , USA"},{"name":"Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard , Boston, Massachusetts , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4773-9817","authenticated-orcid":false,"given":"Kimberly G","family":"Blumenthal","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital , Boston, Massachusetts , USA"},{"name":"Harvard Medical School , Boston, Massachusetts , USA"},{"name":"Edward P. Lawrence Center for Quality and Safety, Massachusetts General Hospital and Massachusetts General Professional Organization , Boston, Massachusetts , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,9,27]]},"reference":[{"key":"2022101811285272000_ofac499-B1"},{"key":"2022101811285272000_ofac499-B2","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1056\/NEJMoa2035389","article-title":"Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine","volume":"384","author":"Baden","year":"2021","journal-title":"N Engl J Med"},{"key":"2022101811285272000_ofac499-B3","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1056\/NEJMc2102131","article-title":"Delayed large local reactions to mRNA-1273 vaccine against SARS-CoV-2","volume":"384","author":"Blumenthal","year":"2021","journal-title":"N Engl J 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