{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T13:36:25Z","timestamp":1789565785644,"version":"build-2803163510"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T00:00:00Z","timestamp":1680048000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100017037","name":"Cepheid","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100017037","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Colonization with multidrug-resistant organisms (MDROs) is a risk factor for subsequent infection. Surveillance for MDROs, including methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, extended-spectrum beta-lactamase-producing Enterobacterales, and carbapenemase-producing organisms, is commonly conducted in hospitals to prevent spread of MDROs, in part to reduce the potential for additional infections. Although colonization is a risk factor for infection, data on colonization with various MDROs are often not considered when selecting anti-infective therapy. There are conflicting data on the strength of the positive and negative predictive values of the colonization test results to guide therapeutic strategies. Defining therapeutic strategies for patients with complicated or drug-resistant infections or to select antimicrobial prophylaxis before performing prostate biopsies often falls under the purview of the antimicrobial stewardship team. Should colonization data, which are often present in the patient's medical record from routine infection prevention measures, be reviewed before selecting therapy for infections or for prophylaxis? In this perspective, we will explore the intersection of infection control and antimicrobial stewardship activities.<\/jats:p>","DOI":"10.1093\/ofid\/ofad176","type":"journal-article","created":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T05:44:36Z","timestamp":1680155076000},"source":"Crossref","is-referenced-by-count":11,"title":["Surveillance and Stewardship: Where Infection Prevention and Antimicrobial Stewardship Intersect"],"prefix":"10.1093","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1220-3118","authenticated-orcid":false,"given":"Fred C","family":"Tenover","sequence":"first","affiliation":[{"name":"Cepheid , Sunnyvale, California , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7686-0670","authenticated-orcid":false,"given":"Debra A","family":"Goff","sequence":"additional","affiliation":[{"name":"College of Pharmacy, The Ohio State University Wexner Medical Center , Columbus, Ohio , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,3,29]]},"reference":[{"key":"2023042014133431400_ofad176-B1","doi-asserted-by":"crossref","first-page":"e169","DOI":"10.1093\/cid\/ciaa1478","article-title":"Infectious Diseases Society of America guidance on the treatment of extended-spectrum \u03b2-lactamase producing enterobacterales (ESBL-E), carbapenem-resistant enterobacterales (CRE), and Pseudomonas aeruginosa with difficult-to-treat resistance (DTR-P. aeruginosa)","volume":"72","author":"Tamma","year":"2021","journal-title":"Clin Infect Dis"},{"key":"2023042014133431400_ofad176-B2","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1586\/14787210.2016.1106940","article-title":"Infection control implications of heterogeneous resistance mechanisms in carbapenem-resistant enterobacteriaceae (CRE)","volume":"14","author":"Goodman","year":"2016","journal-title":"Exp Rev Anti Infect Ther"},{"key":"2023042014133431400_ofad176-B3","article-title":"Comparing the activity of novel antibiotic agents against carbapenem-resistant Enterobacterales clinical isolates","author":"Tamma","journal-title":"Infect Control Hosp Epidemiol"},{"key":"2023042014133431400_ofad176-B4","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.1093\/cid\/ciab452","article-title":"Current paradigms of combination therapy in methicillin-resistant Staphylococcus aureus (MRSA) bacteremia: does it work, which combination, and for which patients?","volume":"73","author":"Rose","year":"2021","journal-title":"Clin Infect Dis"},{"key":"2023042014133431400_ofad176-B5","doi-asserted-by":"crossref","first-page":"E181","DOI":"10.1111\/1469-0691.12132","article-title":"Enterococcal bacteraemia: factors influencing mortality, length of stay and costs of hospitalization","volume":"19","author":"Cheah","year":"2013","journal-title":"Clin Microbiol Infect"},{"key":"2023042014133431400_ofad176-B6","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1164\/rccm.201908-1581ST","article-title":"Diagnosis and treatment of adults with community-acquired pneumonia. An official clinical practice guideline of the American Thoracic Society and Infectious Diseases Society of America","volume":"200","author":"Metlay","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"key":"2023042014133431400_ofad176-B7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/cid\/ciy024","article-title":"The clinical utility of methicillin-resistant Staphylococcus aureus (MRSA) nasal screening to rule out MRSA pneumonia: a diagnostic meta-analysis with antimicrobial stewardship implications","volume":"67","author":"Parente","year":"2018","journal-title":"Clin Infect Dis"},{"key":"2023042014133431400_ofad176-B8","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1093\/cid\/ciy868","article-title":"Methicillin-resistant Staphylococcus aureus nasal screening adds limited value to the choice of empiric antibiotics in community-acquired pneumonia","volume":"68","author":"Burnham","year":"2019","journal-title":"Clin Infect 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