{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:13:39Z","timestamp":1753877619576,"version":"3.41.2"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T00:00:00Z","timestamp":1727395200000},"content-version":"vor","delay-in-days":28,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We report 2 cases of infection by fungi unprecedented in Rwanda. One patient with emergomycosis presented with disseminated disease and prominent cutaneous involvement and one patient with African blastomycosis had cutaneous and osseous disease. These cases illustrate the clinicopathologic and molecular traits of novel dimorphic onygenalean species in Rwanda.<\/jats:p>","DOI":"10.1093\/ofid\/ofae511","type":"journal-article","created":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T09:43:30Z","timestamp":1725615810000},"source":"Crossref","is-referenced-by-count":0,"title":["Systemic Mycoses by Novel Onygenalean Fungal Pathogens <i>Emergomyces<\/i> spp and <i>Blastomyces percursus<\/i> in Rwanda"],"prefix":"10.1093","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1282-2274","authenticated-orcid":false,"given":"Alvaro C","family":"Laga","sequence":"first","affiliation":[{"name":"Department of Pathology, Brigham and Women's Hospital and Harvard Medical School , Boston, Massachusetts ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deogratias","family":"Ruhangaza","sequence":"additional","affiliation":[{"name":"Department of Pathology, Butaro District Hospital. \u00a0 Butaro ,","place":["Rwanda"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annie Isabelle","family":"Izimukwiye","sequence":"additional","affiliation":[{"name":"Department of Pathology, Rwanda Military Hospital , Kigali ,","place":["Rwanda"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raquel","family":"Vilela","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais ,","place":["Brazil"]},{"name":"Microbiology and Molecular Genetics, Biomedical Laboratory Diagnostics, Michigan State University , East Lansing, Michigan ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonel","family":"Mendoza","sequence":"additional","affiliation":[{"name":"Microbiology and Molecular Genetics, Biomedical Laboratory Diagnostics, Michigan State University , East Lansing, Michigan ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,9,6]]},"reference":[{"key":"2024092714522824200_ofae511-B1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11046-020-00428-x","article-title":"Onygenalean fungi as major human and animal pathogens","volume":"185","author":"Chaturvedi","year":"2020","journal-title":"Mycopathologia"},{"key":"2024092714522824200_ofae511-B2","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1056\/NEJMoa1215460","article-title":"A dimorphic fungus causing disseminated infection in South Africa","volume":"369","author":"Kenyon","year":"2013","journal-title":"N Engl J Med"},{"key":"2024092714522824200_ofae511-B3","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1111\/myc.12601","article-title":"Novel taxa of thermally dimorphic systemic pathogens in the Ajellomycetaceae (Onygenales)","volume":"60","author":"Dukik","year":"2017","journal-title":"Mycoses"},{"key":"2024092714522824200_ofae511-B4","doi-asserted-by":"crossref","first-page":"e0009922","DOI":"10.1128\/cmr.00099-22","article-title":"Changes in fungal taxonomy: mycological rationale and clinical implications","volume":"36","author":"Borman","year":"2023","journal-title":"Clin Microbiol Rev"},{"key":"2024092714522824200_ofae511-B5","doi-asserted-by":"crossref","first-page":"e0087323","DOI":"10.1128\/jcm.00873-23","article-title":"A conceptual framework for nomenclatural stability and validity of medically important fungi: a proposed global consensus guideline for fungal name changes supported by ABP, ASM, CLSI, ECMM, ESCMID-EFISG, EUCAST-AFST, FDLC, IDSA, ISHAM, MMSA, and MSGERC","volume":"61","author":"de Hoog","year":"2023","journal-title":"J Clin Microbiol"},{"key":"2024092714522824200_ofae511-B6","doi-asserted-by":"crossref","first-page":"e0010737","DOI":"10.1371\/journal.pntd.0010737","article-title":"Endemic mycoses in South Africa, 2010\u20132020: a decade-long description of laboratory diagnosed cases and prospects for the future","volume":"16","author":"Mapengo","year":"2022","journal-title":"PLoS Negl Trop Dis"},{"key":"2024092714522824200_ofae511-B7","doi-asserted-by":"crossref","first-page":"96","DOI":"10.4269\/ajtmh.1968.17.96","article-title":"Blastomyces dermatitidis infection in the Congo","volume":"17","author":"Gatti","year":"1968","journal-title":"Am J Trop Med Hyg"},{"key":"2024092714522824200_ofae511-B8","doi-asserted-by":"crossref","first-page":"e1560","DOI":"10.1093\/cid\/ciaa1100","article-title":"Blastomycosis in Africa and the Middle East: a comprehensive review of reported cases and reanalysis of historical isolates based on molecular data","volume":"73","author":"Schwartz","year":"2021","journal-title":"Clin Infect Dis"},{"key":"2024092714522824200_ofae511-B9","doi-asserted-by":"crossref","first-page":"e01661-19","DOI":"10.1128\/JCM.01661-19","article-title":"Human Blastomycosis in South Africa caused by Blastomyces percursus and Blastomyces emzantsi sp. nov., 1967 to 2014","volume":"58","author":"Maphanga","year":"2020","journal-title":"J Clin Microbiol"},{"key":"2024092714522824200_ofae511-B10","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.3390\/jof9101039","article-title":"Emergomycosis, an emerging thermally dimorphic fungal infection: a systematic review","volume":"9","author":"Vinayagamoorthy","year":"2023","journal-title":"J Fungi (Basel)"},{"key":"2024092714522824200_ofae511-B11","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.3201\/eid2509.181234","article-title":"Disseminated emergomycosis in a person with HIV infection, Uganda","volume":"25","author":"Rooms","year":"2019","journal-title":"Emerg Infect Dis"},{"key":"2024092714522824200_ofae511-B12","first-page":"512","article-title":"Blastomycose \u00e0 Blastomyces dermatitidis au Rwanda: a propos de trois observations","volume":"A133","author":"Vandepitte","year":"1982","journal-title":"Ann Microbiol (Paris)"},{"key":"2024092714522824200_ofae511-B13","first-page":"415","article-title":"A presumptive case of cutaneous emergomycosis in a female living with HIV, Maseru, Lesotho","volume":"37","author":"Madani","year":"2022","journal-title":"S Afr J Infect Dis"},{"key":"2024092714522824200_ofae511-B14","doi-asserted-by":"crossref","first-page":"993","DOI":"10.3390\/jof8100993","article-title":"Immunologic diagnosis of endemic mycoses","volume":"8","author":"Almeida-Paes","year":"2022","journal-title":"J. Fungi (Basel)"}],"container-title":["Open Forum Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ofid\/advance-article-pdf\/doi\/10.1093\/ofid\/ofae511\/59031263\/ofae511.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ofid\/article-pdf\/11\/9\/ofae511\/59278583\/ofae511.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ofid\/article-pdf\/11\/9\/ofae511\/59278583\/ofae511.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T14:52:42Z","timestamp":1727448762000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ofid\/article\/doi\/10.1093\/ofid\/ofae511\/7750182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,30]]},"references-count":14,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,8,30]]}},"URL":"https:\/\/doi.org\/10.1093\/ofid\/ofae511","relation":{},"ISSN":["2328-8957"],"issn-type":[{"type":"electronic","value":"2328-8957"}],"subject":[],"published-other":{"date-parts":[[2024,9]]},"published":{"date-parts":[[2024,8,30]]},"article-number":"ofae511"}}