{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T04:01:08Z","timestamp":1772078468223,"version":"3.50.1"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>HIV coinfection worsens health outcomes for persons with chronic hepatitis C virus (HCV) infection; however, access to comprehensive Ryan White (RW) HIV care may improve the health of persons with HIV and HCV.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>In a retrospective cohort study, we used surveillance data from Philadelphia's hepatitis and HIV registries for newly reported HCV infections from November 2015 to October 2021. We plotted Kaplan-Meier curves and performed Cox regressions on time to HCV clearance by HIV coinfection status, adjusting for demographic characteristics and HCV report year.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 10 251 persons with newly reported HCV infection were included, of whom 9898 (96.6%) had HCV monoinfection and 353 (3.4%) had HIV coinfection. HCV reports were mostly among residents who were non-Hispanic\/Latine White (n = 3609, 35.2%) and non-Hispanic\/Latine Black (n = 3221, 31.4%) and assigned male sex at birth (n = 6931, 67.8%). At every month of follow-up, having HIV was associated with a higher likelihood of HCV clearance as compared with HCV monoinfection (adjusted hazard ratio, 1.2; 95% CI, 1.1\u20131.4; P &amp;lt; .05). For persons with HIV coinfection, participation in RW support services 2 to 6 times monthly was associated with an increased likelihood (adjusted hazard ratio, 1.7\u20133.1) of HCV clearance at every month of follow-up as compared with persons without RW participation (P &amp;lt; .05).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Among newly reported HCV infections, the likelihood of HCV clearance was higher among persons with HIV coinfection who participated in RW support services. Frequent receipt of supportive services, such as those provided by the national, federally funded RW system, is crucial for HCV elimination.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ofid\/ofaf043","type":"journal-article","created":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T16:38:02Z","timestamp":1738082282000},"source":"Crossref","is-referenced-by-count":1,"title":["People With HIV Are More Likely to Clear Hepatitis C: Role of Ryan White Services, Philadelphia, Pennsylvania, United States"],"prefix":"10.1093","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7001-8319","authenticated-orcid":false,"given":"Marissa","family":"Tan","sequence":"first","affiliation":[{"name":"Cooper Center for Healing , Cooper University Health Care, Camden, New Jersey ,","place":["USA"]},{"name":"Epidemiology Intelligence Service, Division of Workforce Development, Centers for Disease Control and Prevention , Atlanta, Georgia ,","place":["USA"]},{"name":"Hepatitis, Division of Disease Control, Philadelphia Department of Public Health , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0777-5074","authenticated-orcid":false,"given":"Danica","family":"Kuncio","sequence":"additional","affiliation":[{"name":"Hepatitis, Division of Disease Control, Philadelphia Department of Public Health , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eman","family":"Addish","sequence":"additional","affiliation":[{"name":"Hepatitis, Division of Disease Control, Philadelphia Department of Public Health , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9335-5382","authenticated-orcid":false,"given":"Tanner","family":"Nassau","sequence":"additional","affiliation":[{"name":"Division of HIV Health, Philadelphia Department of Public Health , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2908-1345","authenticated-orcid":false,"given":"Dana","family":"Higgins","sequence":"additional","affiliation":[{"name":"Division of Substance Use Prevention and Harm Reduction, Philadelphia Department of Public Health , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Miller","sequence":"additional","affiliation":[{"name":"Division of HIV Health, Philadelphia Department of Public Health , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen","family":"Brady","sequence":"additional","affiliation":[{"name":"Division of HIV Health, Philadelphia Department of Public Health , Philadelphia, Pennsylvania 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Medicaid nonexpansion state","volume":"65","author":"Diepstra","year":"2017","journal-title":"Clin Infect Dis"},{"key":"2025022510074543800_ofaf043-B9","author":"Nassau"},{"key":"2025022510074543800_ofaf043-B10","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1093\/cid\/civ708","article-title":"Ryan White HIV\/AIDS program assistance and HIV treatment outcomes","volume":"62","author":"Bradley","year":"2016","journal-title":"Clin Infect Dis"},{"issue":"suppl 1","key":"2025022510074543800_ofaf043-B11","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1089\/apc.2022.0095","article-title":"Evaluating evidence-informed behavioral health models to improve HIV health outcomes: quantitative findings from the Ryan White HIV\/AIDS program special projects of national significance Black men who have sex with men initiative","volume":"36","author":"Shah","year":"2022","journal-title":"AIDS Patient Care 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