{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:04:09Z","timestamp":1753877049115,"version":"3.41.2"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T00:00:00Z","timestamp":1743724800000},"content-version":"vor","delay-in-days":8,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>We report a case of Kazachstania slooffiae fungemia in a 77-year-old immunocompromised male with gastrointestinal abnormalities including achalasia, gastroparesis, and prior esophagectomy. He presented with sepsis, gastric ischemia, and pleural effusion. To date, only 2 prior cases of Kazachstania slooffiae infection have been reported, both involving nonbloodstream infections.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We reviewed the existing literature and compared clinical, diagnostic, and treatment characteristics across all identified cases.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Kazachstania slooffiae has been identified in critically ill, immunocompromised patients with gastrointestinal anatomic abnormalities, underlying malignancy, and disease. Diagnosis relies on advanced methods such as matrix-assisted laser desorption\/ionization time-of-flight mass spectrometry and DNA sequencing. Antifungal treatments (caspofungin, fluconazole, micafungin) have resulted in favorable outcomes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This review highlights Kazachstania slooffiae as a rare opportunistic pathogen and provides the first evidence for Kazachstania slooffiae as a bloodstream pathogen in humans. Prompt identification and antifungal therapy are critical for managing infections.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ofid\/ofaf209","type":"journal-article","created":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T05:59:37Z","timestamp":1743746377000},"source":"Crossref","is-referenced-by-count":0,"title":["<i>Kazachstania slooffiae<\/i> Fungemia: A Case Report and Literature Review on an Emerging Opportunistic Pathogen in Humans"],"prefix":"10.1093","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-4946-1486","authenticated-orcid":false,"given":"Sarah N","family":"Fortna","sequence":"first","affiliation":[{"name":"Department of Medicine, Indiana University School of Medicine , Indianapolis, Indiana ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4587-6121","authenticated-orcid":false,"given":"David M","family":"Aronoff","sequence":"additional","affiliation":[{"name":"Department of Medicine, Indiana University School of Medicine , Indianapolis, Indiana ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2873-5776","authenticated-orcid":false,"given":"Andrew T","family":"Dysangco","sequence":"additional","affiliation":[{"name":"VA Atlanta Healthcare System , Decatur, Georgia ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,4,4]]},"reference":[{"key":"2025052712083694800_ofaf209-B1","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1056\/NEJMra1315399","article-title":"Invasive candidiasis","volume":"373","author":"Kullberg","year":"2015","journal-title":"N Engl J Med"},{"key":"2025052712083694800_ofaf209-B2","doi-asserted-by":"crossref","first-page":"963","DOI":"10.3390\/pathogens11090963","article-title":"Overview on the infections related to rare Candida 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