{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T10:39:03Z","timestamp":1786963143222,"version":"build-2736575974"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We analyzed the impact of a diagnostic meningitis\/encephalitis polymerase chain reaction panel. Introducing the test resulted in no significantly shortened empiric antibiotic streptococcal\/meningococcal treatment (\u22121 day [95% confidence interval {CI}, 0\u20133 days]; P = .16), nor hospitalization (\u22122 days [95% CI, 0\u20133 days]; P = .86). Empiric treatment duration against Herpesviridae and Listeria monocytogenes remained unchanged, and pathogen-specific diagnoses were not increased.<\/jats:p>","DOI":"10.1093\/ofid\/ofaf241","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T14:49:28Z","timestamp":1745506168000},"source":"Crossref","is-referenced-by-count":2,"title":["Introducing a New Polymerase Chain Reaction Panel\u2013Based Cerebrospinal Fluid Evaluation for Encephalitis and Meningitis: Does It Influence Empiric Treatment Duration, Length of Hospital Stay, and Pathogen-Specific Diagnoses?"],"prefix":"10.1093","volume":"12","author":[{"given":"Fabian","family":"Sidler","sequence":"first","affiliation":[{"name":"Department of Visceral Surgery and Medicine, Inselspital Bern University Hospital, University of Bern , Bern 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