{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T23:25:00Z","timestamp":1778541900333,"version":"3.51.4"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T00:00:00Z","timestamp":1750809600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["75D30121C11953"],"award-info":[{"award-number":["75D30121C11953"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>There is limited knowledge on the extent of antimicrobial stewardship program (ASP) implementation in health care facilities (HCFs) in Latin America.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We performed an evaluation of ASPs in Latin American HCFs from March 2022 to February 2023 using a structured self-assessment survey associated with a scoring system that evaluated leadership support and accountability, resources, antibiotic stewardship actions, education, and antibiotic use (AU) monitoring and reporting. Additionally, we collected monthly AU data (antibiotic consumption and point prevalence surveys) and number of multidrug-resistant infections in medical-surgical intensive care units. Self-assessment scores were correlated with AU through multivariable regression models adjusting for bed size, country of HCF, and incidence of infections (when appropriate).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of the 39 HCFs recruited for the study, all completed the self-assessment, 36 performed the point prevalence survey, and 29 collected antibiotic consumption data. The overall median self-assessment score was 252.5 (IQR, 212.5\u2013285) for a maximum possible score of 335. A high self-assessment score (top quartile) was associated with higher guideline-compliant AU (odds ratio [OR], 8.63; 95% CI, 3.03\u201324.6; P &amp;lt; .001), higher use of directed therapy (OR, 2.11; 95% CI, 1.41\u20133.1; P &amp;lt; .001), and less consumption of anti\u2013methicillin-resistant Staphylococcus aureus agents (OR, \u22128.59; SE = 4.12; P = .037) after adjusting for bed size, country, and incidence of methicillin-resistant S aureus infections.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Higher-level ASP implementation in Latin American HCFs correlated with better compliance with AU guidelines and decreased the use of vancomycin in the intensive care unit, supporting the need to improve resources for ASPs.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ofid\/ofaf364","type":"journal-article","created":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T07:40:43Z","timestamp":1750750843000},"source":"Crossref","is-referenced-by-count":2,"title":["Multicenter Evaluation of Antibiotic Use and Antibiotic Stewardship Programs in Latin American Hospitals"],"prefix":"10.1093","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7374-9678","authenticated-orcid":false,"given":"Valeria","family":"Fabre","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, School of Medicine, Johns Hopkins University , Baltimore, Maryland ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara E","family":"Cosgrove","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, School of Medicine, Johns Hopkins University , Baltimore, Maryland ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yea-Jen","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Health Policy and Management, Johns Hopkins Bloomberg of School of Public Health , Baltimore, Maryland ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Twisha S","family":"Patel","sequence":"additional","affiliation":[{"name":"International Infection Control Branch, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention , Atlanta, Georgia ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda C","family":"Lessa","sequence":"additional","affiliation":[{"name":"International Infection Control Branch, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention , Atlanta, Georgia ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7055-1054","authenticated-orcid":false,"given":"Andrea","family":"Alvarado","sequence":"additional","affiliation":[{"name":"Unidad de Cirugia Cardiovascular de Guatemala , Guatemala ,","place":["Guatemala"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1197-134X","authenticated-orcid":false,"given":"Bowen","family":"Aquiles","sequence":"additional","affiliation":[{"name":"Hospital Sociedad de Lucha Contra el C\u00e1ncer , Guayaquil ,","place":["Ecuador"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana B","family":"Arauz","sequence":"additional","affiliation":[{"name":"Departamento de Medicina, Universidad de Panam\u00e1 ,","place":["Panama"]},{"name":"Hospital Santo Tomas , Panama ,","place":["Panama"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria F","family":"Barberis","sequence":"additional","affiliation":[{"name":"Hospital Nacional Profesor Alejandro Posadas , El Palomar ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Del Carmen","family":"Bangher","sequence":"additional","affiliation":[{"name":"Instituto de Cardiolog\u00eda de Corrientes \u201cJuana Francisca Cabral,\u201d \u00a0 Corrientes ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8227-2022","authenticated-orcid":false,"given":"Maria P","family":"Bernachea","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Conciencia , Neuqu\u00e9n ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marisa L","family":"Bernan","sequence":"additional","affiliation":[{"name":"Hospital Interzonal General de Agudos San Roque , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Canton","sequence":"additional","affiliation":[{"name":"Hospital Punta Pac\u00edfica Salud , Panam\u00e1 ,","place":["Panama"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ximena","family":"Casta\u00f1eda","sequence":"additional","affiliation":[{"name":"Cl\u00ednica De La Mujer , Bogot\u00e1 ,","place":["Colombia"]},{"name":"Hospital Mederi , Bogota ,","place":["Colombia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angel M","family":"Colque","sequence":"additional","affiliation":[{"name":"Complejo M\u00e9dico Churruca Visca , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5135-6047","authenticated-orcid":false,"given":"Rosa","family":"Contreras","sequence":"additional","affiliation":[{"name":"Hospital Dr Marcial V. Quiroga , San Juan ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2830-8552","authenticated-orcid":false,"given":"Wanda","family":"Cornistein","sequence":"additional","affiliation":[{"name":"Hospital Universitario Austral , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia Mabel","family":"Correa","sequence":"additional","affiliation":[{"name":"Hospital Municipal de Trauma Dr Federico Abete , Malvinas Argentinas ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo","family":"Costilla Campero","sequence":"additional","affiliation":[{"name":"Hospital Angel C. Padilla , Tucum\u00e1n ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta Isabel","family":"Chamorro Ayala","sequence":"additional","affiliation":[{"name":"Hospital Zonal General de Agudos Dr Alberto Eurnekian , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lidia","family":"Espinola","sequence":"additional","affiliation":[{"name":"Hospital El Cruce , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clara","family":"Esquivel","sequence":"additional","affiliation":[{"name":"Hospital San Benito , Peten ,","place":["Guatemala"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7720-4098","authenticated-orcid":false,"given":"Cecilia","family":"Ezcurra","sequence":"additional","affiliation":[{"name":"Hospital Alem\u00e1n , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johana","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Hospital Dr Guillermo Rawson , San Juan ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Hospital Dr Guillermo Rawson , San Juan ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia","family":"Frassone","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Universitaria Privada Reina Fabiola , C\u00f3rdoba ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Garcia Cruz","sequence":"additional","affiliation":[{"name":"Hospital Sociedad de Lucha Contra el C\u00e1ncer , Guayaquil ,","place":["Ecuador"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1426-1442","authenticated-orcid":false,"given":"Maria Isabel","family":"Garz\u00f3n","sequence":"additional","affiliation":[{"name":"Hospital Privado Universitario de C\u00f3rdoba , C\u00f3rdoba ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8987-9351","authenticated-orcid":false,"given":"Carlos H","family":"Gomez Quintero","sequence":"additional","affiliation":[{"name":"Cl\u00ednica De La Mujer , Bogot\u00e1 ,","place":["Colombia"]},{"name":"Hospital Militar Central , Bogot\u00e1 ,","place":["Colombia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 A","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Hospital Irma de Lourdes Tzanetatos , Panama ,","place":["Panama"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucrecia","family":"Guaymas","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Provincial de Merlo , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5839-8539","authenticated-orcid":false,"given":"Fausto","family":"Guerrero-Toapanta","sequence":"additional","affiliation":[{"name":"Hospital Carlos Andrade Mar\u00edn , Quito ,","place":["Ecuador"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Lambert","sequence":"additional","affiliation":[{"name":"Hospital El Cruce , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2375-1686","authenticated-orcid":false,"given":"Diego","family":"Laplume","sequence":"additional","affiliation":[{"name":"Hospital Nacional Profesor Alejandro Posadas , El Palomar ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Itzel L","family":"Lopez","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Hospital San Fernando , Panama ,","place":["Panama"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1964-1660","authenticated-orcid":false,"given":"Herberth","family":"Maldonado","sequence":"additional","affiliation":[{"name":"Unidad de Cirugia Cardiovascular de Guatemala , Guatemala ,","place":["Guatemala"]},{"name":"Universidad del Valle de Guatemala , Guatemala ,","place":["Guatemala"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noelia","family":"Ma\u00f1ez","sequence":"additional","affiliation":[{"name":"Hospital Italiano de Buenos Aires , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego M","family":"Maurizi","sequence":"additional","affiliation":[{"name":"Hospital Municipal de Agudos Dr Leonidas Lucero , Bah\u00eda Blanca ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Melgar","sequence":"additional","affiliation":[{"name":"Hospital Roosevelt , Guatemala ,","place":["Guatemala"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florencia","family":"Mesplet","sequence":"additional","affiliation":[{"name":"Hospital Cesar Milstein , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6453-3960","authenticated-orcid":false,"given":"Carlos","family":"Morales Pertuz","sequence":"additional","affiliation":[{"name":"Hospital Del Tunal , Bogot\u00e1 ,","place":["Colombia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Moreno Izquierdo","sequence":"additional","affiliation":[{"name":"Hospital Metropolitano , Quito ,","place":["Ecuador"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciana Gabriela","family":"Moya","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Conciencia , Neuqu\u00e9n ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanina","family":"Nuccetelli","sequence":"additional","affiliation":[{"name":"Instituto de Diagnostico , La Plata ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glendys","family":"N\u00fa\u00f1ez","sequence":"additional","affiliation":[{"name":"Hospital Santo Tomas , Panama ,","place":["Panama"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Argelis","family":"Olmedo","sequence":"additional","affiliation":[{"name":"Hospital Punta Pac\u00edfica Salud , Panam\u00e1 ,","place":["Panama"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bel\u00e9n","family":"Palacio","sequence":"additional","affiliation":[{"name":"Sanatorio Allende Nueva C\u00f3rdoba , C\u00f3rdoba ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Pauluzzi","sequence":"additional","affiliation":[{"name":"Hospital Universitario Austral , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0042-5370","authenticated-orcid":false,"given":"Mariana","family":"de Paz Sierra","sequence":"additional","affiliation":[{"name":"Hospital Italiano de Buenos Aires , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florencia","family":"Pellice","sequence":"additional","affiliation":[{"name":"Hospital Dr Marcial V. Quiroga , San Juan ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loraine","family":"Perez Alvear","sequence":"additional","affiliation":[{"name":"Hospital Del Tunal , Bogot\u00e1 ,","place":["Colombia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla Lorena","family":"Raffo","sequence":"additional","affiliation":[{"name":"Hospital Municipal de Trauma Dr Federico Abete , Malvinas Argentinas ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fanny","family":"Reino","sequence":"additional","affiliation":[{"name":"Hospital Carlos Andrade Mar\u00edn , Quito ,","place":["Ecuador"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ligia","family":"Vence Reyes","sequence":"additional","affiliation":[{"name":"The Panama Clinic , Panama ,","place":["Panama"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerardo","family":"Ricoy","sequence":"additional","affiliation":[{"name":"Complejo M\u00e9dico Churruca Visca , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4862-5486","authenticated-orcid":false,"given":"Viviana E","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Hospital Alem\u00e1n , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3939-1358","authenticated-orcid":false,"given":"Federico","family":"Romero","sequence":"additional","affiliation":[{"name":"Sanatorio Allende Nueva C\u00f3rdoba , C\u00f3rdoba ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0123-8806","authenticated-orcid":false,"given":"Juan J","family":"Romero","sequence":"additional","affiliation":[{"name":"Hospital Vozandes , Quito ,","place":["Ecuador"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariquena","family":"Ruiz","sequence":"additional","affiliation":[{"name":"Hospital Cesar Milstein , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Eugenia","family":"Russo","sequence":"additional","affiliation":[{"name":"Hospital Interzonal General de Agudos San Roque , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graciela","family":"Sadino","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Universitaria Privada Reina Fabiola , C\u00f3rdoba ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy","family":"Sandoval","sequence":"additional","affiliation":[{"name":"Hospital Roosevelt , Guatemala ,","place":["Guatemala"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia","family":"Staffolani","sequence":"additional","affiliation":[{"name":"Maternidad Nuestra Se\u00f1ora De Las Mercedes De Tucum\u00e1n , Tucum\u00e1n ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Jose","family":"Torralvo","sequence":"additional","affiliation":[{"name":"Hospital Mederi , Bogota ,","place":["Colombia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandra M","family":"Urue\u00f1a","sequence":"additional","affiliation":[{"name":"Maternidad Nuestra Se\u00f1ora De Las Mercedes De Tucum\u00e1n , Tucum\u00e1n ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo","family":"Videla","sequence":"additional","affiliation":[{"name":"Instituto de Diagnostico , La Plata ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marisol","family":"Valle","sequence":"additional","affiliation":[{"name":"Hospital Municipal de Agudos Dr Leonidas Lucero , Bah\u00eda Blanca ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Vera Amate Perez","sequence":"additional","affiliation":[{"name":"Hospital Angel C. Padilla , Tucum\u00e1n ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hernan","family":"Vergara-Samur","sequence":"additional","affiliation":[{"name":"Hospital Militar Central , Bogot\u00e1 ,","place":["Colombia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvina","family":"Villamandos","sequence":"additional","affiliation":[{"name":"Instituto de Cardiolog\u00eda de Corrientes \u201cJuana Francisca Cabral,\u201d \u00a0 Corrientes ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7916-0071","authenticated-orcid":false,"given":"Olmedo","family":"Villarreal","sequence":"additional","affiliation":[{"name":"Hospital Irma de Lourdes Tzanetatos , Panama ,","place":["Panama"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Warley","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Provincial de Merlo , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guadalupe","family":"Reyes-Morales","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, School of Medicine, Johns Hopkins University , Baltimore, Maryland ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5820-380X","authenticated-orcid":false,"given":"Rodolfo E","family":"Quiros","sequence":"additional","affiliation":[{"name":"Sanatorio Las Lomas , Buenos Aires ,","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,6,25]]},"reference":[{"key":"2025071806265049800_ofaf364-B1","first-page":"100596","article-title":"Lives lost and disease burden related to antimicrobial resistance in the Americas can no longer be ignored","volume":"26","author":"Undurraga","year":"2023","journal-title":"Lancet Reg Health Am"},{"key":"2025071806265049800_ofaf364-B2","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/S0140-6736(24)01867-1","article-title":"Global burden of bacterial antimicrobial resistance 1990\u20132021: a systematic analysis with forecasts to 2050","volume":"404","author":"GBD 2021 Antimicrobial Resistance Collaborators","year":"2024","journal-title":"Lancet"},{"key":"2025071806265049800_ofaf364-B3","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/S1473-3099(17)30325-0","article-title":"Effect of antibiotic stewardship on the incidence of infection and colonisation with antibiotic-resistant bacteria and Clostridium difficile infection: a systematic review and meta-analysis","volume":"17","author":"Baur","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"2025071806265049800_ofaf364-B4","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1086\/375818","article-title":"A hospitalwide intervention program to optimize the quality of antibiotic use: impact on prescribing practice, antibiotic consumption, cost savings, and bacterial resistance","volume":"37","author":"Bantar","year":"2003","journal-title":"Clin Infect Dis"},{"key":"2025071806265049800_ofaf364-B5"},{"issue":"suppl 1","key":"2025071806265049800_ofaf364-B6","doi-asserted-by":"crossref","first-page":"S53","DOI":"10.1093\/cid\/ciad184","article-title":"Deep dive into gaps and barriers to implementation of antimicrobial stewardship programs in hospitals in Latin America","volume":"77","author":"Fabre","year":"2023","journal-title":"Clin Infect Dis"},{"key":"2025071806265049800_ofaf364-B7","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1093\/cid\/ciad624","article-title":"Stewardship in Brazil: a call for action","volume":"78","author":"Portela de Assis","year":"2024","journal-title":"Clin Infect Dis"},{"key":"2025071806265049800_ofaf364-B8","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s13756-023-01344-7","article-title":"Challenges and success stories of the implementation of infection control and antimicrobial stewardship strategies: proceedings of the 5th Global Ministerial Summit on Patient Safety, 2023","volume":"13","author":"Buchler","year":"2024","journal-title":"Antimicrob Resist Infect Control"},{"key":"2025071806265049800_ofaf364-B9","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1186\/s13756-024-01484-4","article-title":"Contextual barriers to infection prevention and control program implementation in hospitals in Latin America: a mixed methods evaluation","volume":"13","author":"Fabre","year":"2024","journal-title":"Antimicrob Resist Infect Control"},{"key":"2025071806265049800_ofaf364-B10","doi-asserted-by":"crossref","first-page":"ofae620","DOI":"10.1093\/ofid\/ofae620","article-title":"Antibiotic use in medical-surgical intensive care units and general wards in Latin American hospitals","volume":"11","author":"Fabre","year":"2024","journal-title":"Open Forum Infect Dis"},{"key":"2025071806265049800_ofaf364-B11","doi-asserted-by":"crossref","first-page":"s520","DOI":"10.1017\/ice.2020.1203","article-title":"Impact of antimicrobial stewardship programs in Latin American adult intensive care units: PROA-LATAM project","volume":"41","author":"Quir\u00f3s","year":"2020","journal-title":"Infect Control Hosp Epidemiol"},{"key":"2025071806265049800_ofaf364-B12"},{"key":"2025071806265049800_ofaf364-B13","doi-asserted-by":"crossref","first-page":"e68","DOI":"10.1017\/ash.2022.47","article-title":"Antimicrobial stewardship in Latin America: past, present, and future","volume":"2","author":"Fabre","year":"2022","journal-title":"Antimicrob Steward Healthc Epidemiol"},{"key":"2025071806265049800_ofaf364-B14","doi-asserted-by":"crossref","first-page":"e061286","DOI":"10.1136\/bmjopen-2022-061286","article-title":"Identifying context-specific domains for assessing antimicrobial stewardship programmes in Asia: protocol for a scoping review","volume":"12","author":"Vu","year":"2022","journal-title":"BMJ Open"},{"key":"2025071806265049800_ofaf364-B15"},{"key":"2025071806265049800_ofaf364-B16"},{"key":"2025071806265049800_ofaf364-B17","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1017\/ice.2021.80","article-title":"Antimicrobial stewardship programs in adult intensive care units in Latin America: implementation, assessments, and impact on outcomes","volume":"43","author":"Quiros","year":"2022","journal-title":"Infect Control Hosp Epidemiol"},{"key":"2025071806265049800_ofaf364-B18"},{"key":"2025071806265049800_ofaf364-B19","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1086\/591741","article-title":"Recommendations for metrics for multidrug-resistant organisms in healthcare settings: SHEA\/HICPAC position paper","volume":"29","author":"Cohen","year":"2008","journal-title":"Infect Control Hosp Epidemiol"},{"key":"2025071806265049800_ofaf364-B20","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1097\/INF.0000000000001245","article-title":"Handshake stewardship: a highly effective rounding-based antimicrobial optimization service","volume":"35","author":"Hurst","year":"2016","journal-title":"Pediatr Infect Dis J"},{"key":"2025071806265049800_ofaf364-B21","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/S1473-3099(21)00809-4","article-title":"The first WHO global survey on infection prevention and control in health-care facilities","volume":"22","author":"Tomczyk","year":"2022","journal-title":"Lancet Infect Dis"},{"key":"2025071806265049800_ofaf364-B22","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/s13756-024-01400-w","article-title":"Knowledge, attitudes and perceptions of Latin American healthcare workers relating to antibiotic stewardship and antibiotic use: a cross-sectional multi-country study","volume":"13","author":"Fabre","year":"2024","journal-title":"Antimicrob Resist Infect Control"},{"key":"2025071806265049800_ofaf364-B23","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.ajic.2024.10.004","article-title":"Health care workers\u2019 perceptions about infection prevention and control in Latin America","volume":"53","author":"Fabre","year":"2024","journal-title":"Am J Infect Control"},{"key":"2025071806265049800_ofaf364-B24","doi-asserted-by":"crossref","first-page":"e51","DOI":"10.1093\/cid\/ciw118","article-title":"Implementing an antibiotic stewardship program: guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America","volume":"62","author":"Barlam","year":"2016","journal-title":"Clin Infect Dis"},{"key":"2025071806265049800_ofaf364-B25","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1093\/cid\/ciae234","article-title":"Rapid diagnostic tests and antimicrobial stewardship programs for the management of bloodstream infection: what is their relative contribution to improving clinical outcomes? A systematic review and network meta-analysis","volume":"79","author":"Peri","year":"2024","journal-title":"Clin Infect Dis"},{"key":"2025071806265049800_ofaf364-B26","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1086\/664771","article-title":"Evaluation of postprescription review and feedback as a method of promoting rational antimicrobial use: a multicenter intervention","volume":"33","author":"Cosgrove","year":"2012","journal-title":"Infect Control Hosp Epidemiol"}],"container-title":["Open Forum Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ofid\/advance-article-pdf\/doi\/10.1093\/ofid\/ofaf364\/63580252\/ofaf364.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ofid\/article-pdf\/12\/7\/ofaf364\/63580252\/ofaf364.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ofid\/article-pdf\/12\/7\/ofaf364\/63580252\/ofaf364.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T10:27:01Z","timestamp":1752834421000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ofid\/article\/doi\/10.1093\/ofid\/ofaf364\/8173784"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,25]]},"references-count":26,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,6,30]]}},"URL":"https:\/\/doi.org\/10.1093\/ofid\/ofaf364","relation":{},"ISSN":["2328-8957"],"issn-type":[{"value":"2328-8957","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,7]]},"published":{"date-parts":[[2025,6,25]]},"article-number":"ofaf364"}}