{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T21:19:24Z","timestamp":1783977564233,"version":"3.55.0"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"vor","delay-in-days":14,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Edinburgh Clinical Academic Track"},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["214178\/Z\/18\/Z"],"award-info":[{"award-number":["214178\/Z\/18\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We identified a high prevalence of glycopeptide heteroresistance amongst coagulase-negative staphylococci (41.4%, 95% confidence interval 30.7\u201352.9; meta-analysis including n = 1432 isolates). Heteroresistance was associated with methicillin resistance, did not require glycopeptide exposure, and may be more prevalent among isolates from invasive infections. Heteroresistance may represent an under-appreciated reason for treatment failure of CoNS infections.<\/jats:p>","DOI":"10.1093\/ofid\/ofaf494","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T09:32:22Z","timestamp":1755163942000},"source":"Crossref","is-referenced-by-count":3,"title":["Glycopeptide Heteroresistance Among Coagulase-Negative Staphylococci: A Systematic Review and Meta-analysis"],"prefix":"10.1093","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9873-8243","authenticated-orcid":false,"given":"Clark D","family":"Russell","sequence":"first","affiliation":[{"name":"Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh , Edinburgh ,","place":["UK"]},{"name":"NHS Lothian Infection Service, Royal Infirmary of Edinburgh , Edinburgh ,","place":["UK"]},{"name":"Clinical Infection Research Group, Western General Hospital , Edinburgh 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