{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T15:20:03Z","timestamp":1784647203134,"version":"3.55.0"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:00:00Z","timestamp":1758758400000},"content-version":"vor","delay-in-days":27,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Increased prevalence of reduced bone mineral density (BMD) is well documented in persons infected with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or both. This study's purpose was to determine if an association exists between dietary calcium intake and BMD in these patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Participants were individuals with virologically suppressed HIV or untreated HCV monoinfections, those with HIV\/HCV coinfection, and noninfected controls. The Hertzler-Frary dietary calcium questionnaire documented calcium intake with calcium amounts based on the US Department of Agriculture nutrient database. BMD was measured at baseline by dual-energy x-ray absorptiometry, and \u03c72 tests were used to assess the relationship between BMD and infection status. One-way analysis of covariance was used to compare calcium intake data with the prevalence of normal BMD and osteoporosis by infection group. Adjustments were made for race, age, body mass index, and smoking status. Spearman correlation was used to identify relationships between calcium intake from foods\/beverages and BMD.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 452 men were recruited into the study. Osteoporosis and osteopenia were prevalent, but there was no association between infection group and BMD result (\u03c72(6) = 6.813; P = .34). Only HCV-infected patients with osteoporosis had lower calcium intake than patients with normal BMD (mean difference, 409 mg\/d [95% confidence interval, 35\u2013784 mg\/d]; P = .03).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>In this study population, dietary calcium intake was correlated with reduced BMD only in patients with HCV monoinfection.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ofid\/ofaf562","type":"journal-article","created":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T13:00:13Z","timestamp":1758805213000},"source":"Crossref","is-referenced-by-count":1,"title":["Calcium Intake and Bone Mineral Density in People With HIV and\/or Chronic Hepatitis C"],"prefix":"10.1093","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0698-2717","authenticated-orcid":false,"given":"Zoey B","family":"Temesgen","sequence":"first","affiliation":[{"name":"University of Minnesota Medical School , Minneapolis, Minnesota ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9179-6697","authenticated-orcid":false,"given":"Zelalem","family":"Temesgen","sequence":"additional","affiliation":[{"name":"Public Health, Infectious Diseases, and Occupational Medicine, Mayo Clinic , Rochester, Minnesota ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9794-0389","authenticated-orcid":false,"given":"Roger J","family":"Bedimo","sequence":"additional","affiliation":[{"name":"Infectious Diseases Section, VA North Texas Health Care System, The University of Texas Southwestern Medical Center at Dallas , Dallas, Texas ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,9,25]]},"reference":[{"key":"2025092509000676100_ofaf562-B1","doi-asserted-by":"crossref","first-page":"e1004325","DOI":"10.1371\/journal.pmed.1004325","article-title":"The forecasted prevalence of comorbidities and multimorbidity in people with HIV in the United States through the year 2030: a modeling study","volume":"21","author":"Althoff","year":"2024","journal-title":"PLoS Med"},{"key":"2025092509000676100_ofaf562-B2","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1111\/hiv.13139","article-title":"Trends of age-related non-communicable diseases in people living with HIV and comparison with uninfected controls: a nationwide population-based study in South Korea","volume":"22","author":"Kim","year":"2021","journal-title":"HIV 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(Baltimore)"},{"key":"2025092509000676100_ofaf562-B33","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1086\/656417","article-title":"Comparison of changes in bone density and turnover with abacavir-lamivudine versus tenofovir-emtricitabine in HIV-infected adults: 48-week results from the ASSERT study","volume":"51","author":"Stellbrink","year":"2010","journal-title":"Clin Infect Dis"},{"key":"2025092509000676100_ofaf562-B34","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1093\/infdis\/jir188","article-title":"Bone mineral density and fractures in antiretroviral-naive persons randomized to receive abacavir-lamivudine or tenofovir disoproxil fumarate-emtricitabine along with efavirenz or atazanavir-ritonavir: AIDS Clinical Trials Group A5224s, a substudy of ACTG A5202","volume":"203","author":"McComsey","year":"2011","journal-title":"J Infect Dis"}],"container-title":["Open Forum Infectious 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