{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:03:10Z","timestamp":1792789390099,"version":"4.5.0"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"vor","delay-in-days":12,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004911","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","award":["E-26\/211.565\/2019"],"award-info":[{"award-number":["E-26\/211.565\/2019"]}],"id":[{"id":"10.13039\/501100004911","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004911","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","award":["CNE E-26\/200.935\/2022"],"award-info":[{"award-number":["CNE E-26\/200.935\/2022"]}],"id":[{"id":"10.13039\/501100004911","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004911","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","award":["JCNE E-26\/200.157\/2023"],"award-info":[{"award-number":["JCNE E-26\/200.157\/2023"]}],"id":[{"id":"10.13039\/501100004911","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004911","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","award":["SEI-260003\/019669\/2022"],"award-info":[{"award-number":["SEI-260003\/019669\/2022"]}],"id":[{"id":"10.13039\/501100004911","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020655","name":"European Health and Digital Executive Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020655","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["311562\/2021\u20133"],"award-info":[{"award-number":["311562\/2021\u20133"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["421620\/2023-4"],"award-info":[{"award-number":["421620\/2023-4"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["307748\/2025-1"],"award-info":[{"award-number":["307748\/2025-1"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006506","name":"Brazilian Ministry of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006506","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Oropouche virus (OROV), an arbovirus causing acute febrile illness, was mostly restricted to the Amazon basin until 2023, when a reassortant lineage spread across Latin America. Increasing numbers of cases have subsequently been reported in extra-Amazonian regions of Brazil. However, follow-up and detailed clinical description is limited. This study aimed to describe viral, clinical, and epidemiological characteristics of OROV cases in the Brazilian states of Rio de Janeiro and Minas Gerais.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This longitudinal study enrolled adults with OROV exposure. Clinical and laboratorial data were assessed, and serum, urine, and saliva samples were tested for OROV RNA and sequenced.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From December 2024 to May 2025, 55 OROV cases were recruited (median age: 46, 65% female). The novel OROV reassortant was confirmed by RNA sequencing. The acute phase was characterized by headache (87%), malaise (87%), fever (82%), myalgia (75%), and rash (45%). Recurrence of symptoms occurred in one-third of participants, including malaise (53%), fever (41%), arthralgia (41%), and chills (41%), but without resurgence of viral load. Viral RNA in serum and saliva was primarily detected in the first week of disease, and beyond the third week in urine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Cases appeared in clusters and rash was frequently observed. Symptoms returned after 1 week, indicating the importance of patient follow-up. Cases either lived near banana plantations or participated in recreational activities at waterfalls, raising concerns about ecotourism in the Atlantic Forest. Since OROV RNA was detectable in urine for a prolonged period, urine samples may be useful for diagnosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ofid\/ofaf736","type":"journal-article","created":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T13:20:00Z","timestamp":1764854400000},"source":"Crossref","is-referenced-by-count":4,"title":["Viral, Clinical, and Epidemiological Characteristics of Oropouche Fever in Southeastern Brazil"],"prefix":"10.1093","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3373-0408","authenticated-orcid":false,"given":"Ezequias Batista","family":"Martins","sequence":"first","affiliation":[{"name":"Laborat\u00f3rio de Doen\u00e7as Febris Agudas, Instituto Nacional de Infectologia Evandro Chagas, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]},{"name":"Departamento de Doen\u00e7as infecciosas e Parasit\u00e1rias, Universidade Federal Fluminense , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otilia","family":"Lupi","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Doen\u00e7as Febris Agudas, Instituto Nacional de Infectologia Evandro Chagas, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4062-3785","authenticated-orcid":false,"given":"Ot\u00e1vio Melo","family":"Esp\u00edndola","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Doen\u00e7as Febris Agudas, Instituto Nacional de Infectologia Evandro Chagas, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"de Bruycker-Nogueira","sequence":"additional","affiliation":[{"name":"Instituto Oswaldo Cruz, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ighor","family":"Arantes","sequence":"additional","affiliation":[{"name":"Instituto Oswaldo Cruz, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3870-871X","authenticated-orcid":false,"given":"Clarisse da Silveira","family":"Bressan","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Doen\u00e7as Febris Agudas, Instituto Nacional de Infectologia Evandro Chagas, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anielle","family":"de Pina-Costa","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Doen\u00e7as Febris Agudas, Instituto Nacional de Infectologia Evandro Chagas, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]},{"name":"Departamento de Doen\u00e7as infecciosas e Parasit\u00e1rias, Universidade Federal Fluminense , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele Fernanda Borges","family":"da Silva","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Doen\u00e7as Febris Agudas, Instituto Nacional de Infectologia Evandro Chagas, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tulio Vieira","family":"Mendes","sequence":"additional","affiliation":[{"name":"Departamento de Cl\u00ednica M\u00e9dica, Universidade Federal de Ju\u00edz de Fora , Minas Gerais ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rog\u00e9rio Valls","family":"de Souza","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Doen\u00e7as Febris Agudas, Instituto Nacional de Infectologia Evandro Chagas, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0089-6682","authenticated-orcid":false,"given":"Manuela da Costa","family":"Medeiros","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Doen\u00e7as Febris Agudas, Instituto Nacional de Infectologia Evandro Chagas, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4618-5831","authenticated-orcid":false,"given":"Diego Henrique","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Secretaria Municipal de Sa\u00fade de Piau , Minas Gerais ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uindianara Thereza","family":"da Silva","sequence":"additional","affiliation":[{"name":"Secretaria Municipal de Sa\u00fade de Piau , Minas Gerais ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo Silva","family":"Silv\u00e9rio","sequence":"additional","affiliation":[{"name":"Departamento de Cl\u00ednica M\u00e9dica, Universidade Federal de Ju\u00edz de Fora , Minas Gerais ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana Flores","family":"Mamani","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Doen\u00e7as Febris Agudas, Instituto Nacional de Infectologia Evandro Chagas, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marise","family":"Mattos","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Doen\u00e7as Febris Agudas, Instituto Nacional de Infectologia Evandro Chagas, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trevon Louis","family":"Fuller","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Doen\u00e7as Febris Agudas, Instituto Nacional de Infectologia Evandro Chagas, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0047-6538","authenticated-orcid":false,"given":"Lusiele","family":"Guaraldo","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Doen\u00e7as Febris Agudas, Instituto Nacional de Infectologia Evandro Chagas, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe Gomes","family":"Naveca","sequence":"additional","affiliation":[{"name":"Instituto Oswaldo Cruz, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]},{"name":"Instituto Le\u00f4nidas e Maria Deane, Funda\u00e7\u00e3o Oswaldo Cruz , Amaz\u00f4nia ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzalo","family":"Bello","sequence":"additional","affiliation":[{"name":"Instituto Oswaldo Cruz, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Maria","family":"Bispo de Filippis","sequence":"additional","affiliation":[{"name":"Instituto Oswaldo Cruz, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3545-5238","authenticated-orcid":false,"given":"Guilherme Amaral","family":"Calvet","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Doen\u00e7as Febris Agudas, Instituto Nacional de Infectologia Evandro Chagas, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9555-7976","authenticated-orcid":false,"given":"Patricia","family":"Brasil","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Doen\u00e7as Febris Agudas, Instituto Nacional de Infectologia Evandro Chagas, Funda\u00e7\u00e3o Oswaldo Cruz , Rio de Janeiro ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"OROV Outbreak Research Group (OrORG)","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia Maria Braga","family":"Mello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario Sergio","family":"Ribeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela Silva","family":"Vidal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Cony","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debora Fontenelle","family":"dos Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia Cristina","family":"de Carvalho Cardoso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Giordano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Braga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciane","family":"de Souza Velasque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thais Pires","family":"Trindade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leticia Lopes","family":"Corr\u00eaa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"Moronoe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heloisa","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Moraes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Penetra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Brendolin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cintia Damasceno","family":"dos Santos Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina Cardoso","family":"dos Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla Santos","family":"de Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Desiree","family":"dos Santos Nunes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos Proen\u00e7a","family":"Moura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelle Aline","family":"dos Santos Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"de Lima Cunha da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia Lowen Levy","family":"Chailhoub","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda Thereza","family":"de Assis Greggio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda Moreira","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josiani Pereira","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur Cabral","family":"Gon\u00e7alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olavo","family":"dos Santos Pereira Junior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livia Mara","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,1,7]]},"reference":[{"key":"2026010712315188000_ofaf736-B1","doi-asserted-by":"crossref","first-page":"574","DOI":"10.4269\/ajtmh.1961.10.574","article-title":"Oropouche virus: a new human disease agent from Trinidad, West Indies","volume":"10","author":"Anderson","year":"1961","journal-title":"Am J Trop Med Hyg"},{"key":"2026010712315188000_ofaf736-B2","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.3201\/eid3010.240900","article-title":"Oropouche fever, Cuba, May 2024","volume":"30","author":"Benitez","year":"2024","journal-title":"Emerg Infect Dis"},{"key":"2026010712315188000_ofaf736-B3","volume-title":"Epidemiological update oropouche in the region of the americas\u201413 August 2025","author":"Pan American Health Organization, World Health Organization","year":"2025"},{"key":"2026010712315188000_ofaf736-B4","doi-asserted-by":"crossref","first-page":"3509","DOI":"10.1038\/s41591-024-03300-3","article-title":"Human outbreaks of a novel reassortant oropouche virus in the Brazilian Amazon region","volume":"30","author":"Naveca","year":"2024","journal-title":"Nat Med"},{"key":"2026010712315188000_ofaf736-B5","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/S1473-3099(24)00687-X","article-title":"Expansion of Oropouche virus in non-endemic Brazilian regions: analysis of genomic characterisation and ecological drivers","volume":"25","author":"Gr\u00e4f","year":"2025","journal-title":"Lancet Infect Dis"},{"key":"2026010712315188000_ofaf736-B6","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.3201\/eid3107.250468","article-title":"Estimation of incubation period for oropouche virus disease among travel-associated cases, 2024\u20132025","volume":"31","author":"Guagliardo","year":"2025","journal-title":"Emerg Infect Dis"},{"key":"2026010712315188000_ofaf736-B7","first-page":"e136","article-title":"[Key clinical manifestations to differentiate Oropouche fever from dengue and other arboviral diseases: a living systematic reviewRevis\u00e3o sistem\u00e1tica viva das manifesta\u00e7\u00f5es cl\u00ednicas da febre do Oropouche: caracter\u00edsticas-chave para diferenci\u00e1-la da dengue e de outras arboviroses]","volume":"48","author":"Tortosa","year":"2024","journal-title":"Rev Panam Salud Publica"},{"key":"2026010712315188000_ofaf736-B8","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.4269\/ajtmh.16-0672","article-title":"Oropouche virus: clinical, epidemiological, and molecular aspects of a neglected orthobunyavirus","volume":"96","author":"Travassos da Rosa","year":"2017","journal-title":"Am J Trop Med Hyg"},{"key":"2026010712315188000_ofaf736-B9","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1007\/s13365-021-00987-9","article-title":"Neurological disease caused by Oropouche virus in northern Brazil: should it be included in the scope of clinical neurological diseases?","volume":"27","author":"Chiang","year":"2021","journal-title":"J Neurovirol"},{"key":"2026010712315188000_ofaf736-B10","doi-asserted-by":"crossref","first-page":"2711","DOI":"10.3201\/eid2710.204760","article-title":"Outbreak of oropouche virus in French guiana","volume":"27","author":"Gaillet","year":"2021","journal-title":"Emerg Infect Dis"},{"key":"2026010712315188000_ofaf736-B11","doi-asserted-by":"crossref","first-page":"380","DOI":"10.3201\/eid2502.181189","article-title":"Oropouche virus-associated aseptic meningoencephalitis, southeastern Brazil","volume":"25","author":"Vernal","year":"2019","journal-title":"Emerg Infect Dis"},{"key":"2026010712315188000_ofaf736-B12","doi-asserted-by":"crossref","first-page":"199318","DOI":"10.1016\/j.virusres.2024.199318","article-title":"Oropouche virus: a neglected global arboviral threat","volume":"341","author":"Zhang","year":"2024","journal-title":"Virus Res"},{"key":"2026010712315188000_ofaf736-B13","volume-title":"Painel epidemiol\u00f3gico","author":"Brazilian Ministry of Health","year":"2025"},{"key":"2026010712315188000_ofaf736-B14","doi-asserted-by":"crossref","first-page":"e439","DOI":"10.1016\/S1473-3099(23)00740-5","article-title":"Emergence of oropouche fever in Latin America: a narrative review","volume":"24","author":"Wesselmann","year":"2024","journal-title":"Lancet Infect Dis"},{"key":"2026010712315188000_ofaf736-B15","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.micinf.2017.11.013","article-title":"Oropouche fever, an emergent disease from the Americas","volume":"20","author":"Romero-Alvarez","year":"2018","journal-title":"Microbes Infect"},{"key":"2026010712315188000_ofaf736-B16","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1590\/0074-02760160062","article-title":"Multiplexed reverse transcription real-time polymerase chain reaction for simultaneous detection of Mayaro, Oropouche, and Oropouche-like viruses","volume":"112","author":"Naveca","year":"2017","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"2026010712315188000_ofaf736-B17","doi-asserted-by":"crossref","first-page":"2445","DOI":"10.1128\/JCM.39.7.2445-2452.2001","article-title":"Diagnosis of Oropouche virus infection using a recombinant nucleocapsid protein-based enzyme immunoassay","volume":"39","author":"Saeed","year":"2001","journal-title":"J Clin Microbiol"},{"key":"2026010712315188000_ofaf736-B18","doi-asserted-by":"crossref","DOI":"10.1201\/9780429340512","volume-title":"Principles of biostatistics","author":"Pagano","year":"2022","edition":"Third edition"},{"key":"2026010712315188000_ofaf736-B19","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.3201\/eid3011.241220","article-title":"Reemergence of oropouche virus in the americas and risk for spread in the United States and its territories, 2024","volume":"30","author":"Guagliardo","year":"2024","journal-title":"Emerg Infect Dis"},{"key":"2026010712315188000_ofaf736-B20","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.3201\/eid3010.241088","article-title":"Spatiotemporal epidemiology of oropouche fever, Brazil, 2015\u20132024","volume":"30","author":"Martins-Filho","year":"2024","journal-title":"Emerg Infect Dis"},{"key":"2026010712315188000_ofaf736-B21","doi-asserted-by":"crossref","first-page":"e0012962","DOI":"10.1371\/journal.pntd.0012962","article-title":"Clinical presentation of Oropouche virus infection: a systematic review and meta-analysis","volume":"19","author":"Wang","year":"2025","journal-title":"PLoS Negl Trop Dis"},{"key":"2026010712315188000_ofaf736-B22","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.3201\/eid3106.241946","article-title":"Emergence of oropouche virus in esp\u00edrito santo state, Brazil, 2024","volume":"31","author":"Delatorre","year":"2025","journal-title":"Emerg Infect Dis"},{"key":"2026010712315188000_ofaf736-B23","first-page":"001857","article-title":"Oropouche virus infection induces ROS production and oxidative stress in liver and spleen of mice","volume":"104","author":"da Silva Menegatto","year":"2023","journal-title":"J Gen Virol"},{"key":"2026010712315188000_ofaf736-B24","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1590\/S0036-46651989000400011","article-title":"1st register of an epidemic caused by Oropouche virus in the states of Maranh\u00e3o and Goi\u00e1s, Brazil","volume":"31","author":"Vasconcelos","year":"1989","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"2026010712315188000_ofaf736-B25","doi-asserted-by":"crossref","first-page":"769","DOI":"10.15585\/mmwr.mm7335e1","article-title":"Oropouche virus disease among U.S. Travelers\u2014united States, 2024","volume":"73","author":"Morrison","year":"2024","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2026010712315188000_ofaf736-B26","doi-asserted-by":"crossref","first-page":"149","DOI":"10.4269\/ajtmh.1981.30.149","article-title":"Oropouche virus. I. A review of clinical, epidemiological, and ecological findings","volume":"30","author":"Pinheiro","year":"1981","journal-title":"Am J Trop Med Hyg"},{"key":"2026010712315188000_ofaf736-B27","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/s41541-022-00456-2","article-title":"Baseline mapping of Oropouche virology, epidemiology, therapeutics, and vaccine research and development","volume":"7","author":"Files","year":"2022","journal-title":"NPJ Vaccines"},{"key":"2026010712315188000_ofaf736-B28","doi-asserted-by":"crossref","first-page":"3299","DOI":"10.1128\/JCM.41.7.3299-3305.2003","article-title":"Rapid detection of human pathogenic orthobunyaviruses","volume":"41","author":"Weidmann","year":"2003","journal-title":"J Clin Microbiol"},{"key":"2026010712315188000_ofaf736-B29","doi-asserted-by":"crossref","first-page":"164","DOI":"10.7883\/yoken.JJID.2019.296","article-title":"Oropouche virus detection in febrile patients\u2019 Saliva and urine samples in salvador, Bahia, Brazil","volume":"73","author":"Fonseca","year":"2020","journal-title":"Jpn J Infect Dis"},{"key":"2026010712315188000_ofaf736-B30","doi-asserted-by":"crossref","first-page":"e190338","DOI":"10.1590\/0074-02760190338","article-title":"Oropouche virus detection in saliva and urine","volume":"115","author":"do Nascimento","year":"2020","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"2026010712315188000_ofaf736-B31","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.3201\/eid3012.241470","article-title":"Replication-competent oropouche virus in semen of traveler returning to Italy from Cuba, 2024","volume":"30","author":"Castilletti","year":"2024","journal-title":"Emerg Infect Dis"},{"key":"2026010712315188000_ofaf736-B32","doi-asserted-by":"crossref","first-page":"e64","DOI":"10.1016\/S1473-3099(24)00815-6","article-title":"Persistence of Oropouche virus in body fluids among imported cases in France, 2024","volume":"25","author":"Gourjault","year":"2025","journal-title":"Lancet Infect Dis"},{"key":"2026010712315188000_ofaf736-B33","doi-asserted-by":"crossref","first-page":"17924","DOI":"10.1038\/s41598-019-54223-w","article-title":"IFN-\u03b1 as a time-sensitive biomarker during Oropouche virus infection in early and late seroconverters","volume":"9","author":"de Oliveira","year":"2019","journal-title":"Sci Rep"},{"key":"2026010712315188000_ofaf736-B34","author":"Centers for Disease Control and Prevention"}],"container-title":["Open Forum Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ofid\/article-pdf\/13\/1\/ofaf736\/66293832\/ofaf736.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ofid\/article-pdf\/13\/1\/ofaf736\/66293832\/ofaf736.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T17:34:10Z","timestamp":1767807250000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ofid\/article\/doi\/10.1093\/ofid\/ofaf736\/8416504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,26]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,12,26]]}},"URL":"https:\/\/doi.org\/10.1093\/ofid\/ofaf736","relation":{},"ISSN":["2328-8957"],"issn-type":[{"value":"2328-8957","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,1]]},"published":{"date-parts":[[2025,12,26]]},"article-number":"ofaf736"}}