{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T16:52:06Z","timestamp":1774630326206,"version":"3.50.1"},"reference-count":47,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T00:00:00Z","timestamp":1772236800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Amazonian toxoplasmosis is classically associated with severe disease in hospitalized adults. However, little is known about milder outpatient forms in French Guiana.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed 174 immunocompetent adults diagnosed with acute toxoplasmosis in French Guiana (2002\u20132019), comparing clinical and laboratory features between hospitalized (HPs) and outpatient (OPs) cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Seventy-four patients (43%) were OPs. Fever (93%), lymphadenopathy (62%), and digestive symptoms (56%) predominated among OPs, while respiratory symptoms, anemia, and hyponatremia predicted hospitalization (aOR 9.8, 3.9, and 5.4, respectively). Parasitaemia was detected in 27% of OPs but genotyping succeeded only in HPs, all infected by Toxoplasma gondii strains of the Amazonian population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Mild parasitaemic forms of toxoplasmosis occur in immunocompetent adults in French Guiana. The clinical spectrum of toxoplasmosis in French Guiana appears broader than previously described, extending beyond the severe forms typically associated with strains of the Amazonian population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ofid\/ofag087","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T12:39:51Z","timestamp":1772109591000},"source":"Crossref","is-referenced-by-count":0,"title":["Toxoplasmosis Acquired in French Guiana in Immunocompetent Adults: Case Series From 2002 to 2019, With a Focus on Outpatients"],"prefix":"10.1093","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-9541-0195","authenticated-orcid":false,"given":"Nolwenn","family":"Vidal","sequence":"first","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Department, Limoges University Hospital , Limoges ,","place":["France"]},{"name":"Infectious Diseases and Tropical Medicine Unit, French Guiana University Hospital , Cayenne ,","place":["French Guiana"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1629-1194","authenticated-orcid":false,"given":"Jean-Fran\u00e7ois","family":"Faucher","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Department, Limoges University Hospital , Limoges ,","place":["France"]},{"name":"Inserm U1094, IRD UMR270, Univ. Limoges, Limoges University Hospital, EpiMaCT\u2014Epidemiology of Chronic Diseases in Tropical Zone, Institute of Epidemiology and Global Health\u2014Michel Dumas, OmegaHealth , Limoges ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romain","family":"Blaizot","sequence":"additional","affiliation":[{"name":"Dermatology Unit, French Guiana University Hospital , Cayenne ,","place":["French Guiana"]},{"name":"Tropical Biome and Immunophysiopathology, University of Cayenne , Cayenne ,","place":["French Guiana"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"Pommier de SAnti","sequence":"additional","affiliation":[{"name":"French Armed Forces Centre for Epidemiology and Public Health , Marseille ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Audrey","family":"Valdes","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Unit, French Guiana University Hospital , Cayenne ,","place":["French Guiana"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymonde","family":"Tabi","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Unit, French Guiana University Hospital , Cayenne ,","place":["French Guiana"]},{"name":"GMF Clinique Azur , Qu\u00e9bec ,","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lokman","family":"Galal","sequence":"additional","affiliation":[{"name":"Inserm U1094, IRD UMR270, Univ. 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Limoges, Limoges University Hospital, EpiMaCT\u2014Epidemiology of Chronic Diseases in Tropical Zone, Institute of Epidemiology and Global Health\u2014Michel Dumas, OmegaHealth , Limoges ,","place":["France"]},{"name":"National Reference Centre (NRC) for Toxoplasmosis, Limoges University Hospital , Limoges ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Laure","family":"Dard\u00e9","sequence":"additional","affiliation":[{"name":"Inserm U1094, IRD UMR270, Univ. 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