{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T07:49:20Z","timestamp":1776412160404,"version":"3.51.2"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007270","name":"University of Michigan","doi-asserted-by":"publisher","award":["5 NU38FT000002-02-00"],"award-info":[{"award-number":["5 NU38FT000002-02-00"]}],"id":[{"id":"10.13039\/100007270","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100025287","name":"Center for Forecasting and Outbreak Analytics","doi-asserted-by":"publisher","award":["CDC-RFA-FT-23-0069"],"award-info":[{"award-number":["CDC-RFA-FT-23-0069"]}],"id":[{"id":"10.13039\/100025287","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Increasing the precision of outbreak containment for emerging virus strains requires real-time virus identification that can be integrated with specific public health actions. During the SARS-CoV-2 pandemic, we established a multisector partnership to support rapid genomically informed containment response. This system was in place prior to emergence of the first cluster of SARS-CoV-2 cases with lineage B.1.1.7 in the state of Michigan, which was identified through intensive university-led surveillance sampling and rapid, targeted sequencing. Sequencing data were integrated in real time with a collaborative investigation and response led by the local and state health departments, with university and athletic medicine COVID-19 response teams. In this response, subsequent sampling and just-in-time sequencing were specifically directed toward first- and second-order contacts of B.1.1.7 cases. A total of 50 cases of B.1.1.7-lineage SARS-CoV-2 were identified in this outbreak, which was due to 3 coincident introductions of B.1.1.7-lineage SARS-CoV-2 in the background of a large number of non-B.1.1.7 cases. This initial outbreak was contained, as all subsequent B.1.1.7 infections in the university and surrounding community were due to genetically distinct lineages. This investigation demonstrates the successful implementation of a genomically informed outbreak response that can be extended to university campuses and other settings at high risk for rapid emergence of new viruses or viral variants.<\/jats:p>","DOI":"10.1093\/ofid\/ofag096","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T11:38:34Z","timestamp":1774957114000},"source":"Crossref","is-referenced-by-count":0,"title":["Containment of a Multi-index B.1.1.7 Outbreak on a University Campus Through a Genomically Informed Public Health Response"],"prefix":"10.1093","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5771-8895","authenticated-orcid":false,"given":"Emily T","family":"Martin","sequence":"first","affiliation":[{"name":"University of Michigan , Ann Arbor, Michigan ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam S","family":"Lauring","sequence":"additional","affiliation":[{"name":"University 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