{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T15:13:46Z","timestamp":1778080426643,"version":"3.51.4"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T00:00:00Z","timestamp":1775088000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["R01DA054553"],"award-info":[{"award-number":["R01DA054553"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["U2CDA050098"],"award-info":[{"award-number":["U2CDA050098"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01HL160325"],"award-info":[{"award-number":["R01HL160325"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Doxycycline postexposure prophylaxis (doxy-PEP) is a low-cost, effective strategy for preventing syphilis and other bacterial sexually transmitted infections among men who have sex with men and transgender women, yet doxy-PEP remains underused by young black sexual and gender minorities (YBSGM). This analysis examined sociodemographic, sexual health, and substance use factors associated with interest in doxy-PEP among a human immunodeficiency virus (HIV) status\u2013neutral cohort of YBSGM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Neighborhoods and Networks Phase 2 (N2P2) cohort included YBSGM, and our primary outcome was interest in doxy-PEP. Generalized linear models were fit to calculate the unadjusted and adjusted relative risks (RRs) between interest in doxy-PEP and sociodemographic and health factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 538 participants were included in the analysis, with 59.9% reporting interest in doxy-PEP. Participants interested in doxy-PEP were older (RR, 1.02 [95% confidence interval (CI), 1.00\u20131.04]; P = .04), more likely to be living with HIV (1.25 [1.08\u20131.44]; P &amp;lt; .01), and more likely to have a history of syphilis (1.45 [1.23\u20131.70]; P &amp;lt; .01). Self-report stimulant use (RR, 1.28 [95% CI, 1.15\u20131.53]; P &amp;lt; .01) and group sex (1.32 [1.15\u20131.53]; P &amp;lt; .01) were greater among those interested in doxy-PEP. When adjusted for age, HIV status, and stimulant use, history of syphilis (adjusted RR, 1.17 [95% CI, 1.05\u20131.31]; P = .01) and group sex (1.14 [1.02\u20131.28]; P = .02) remained associated with interest in doxy-PEP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>YBSGM who were interested in doxy-PEP were more likely to have had a syphilis diagnosis and participate in group sex. YBSGM with these risk factors represent an important demographic for the scale-up of doxy-PEP use.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ofid\/ofag176","type":"journal-article","created":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T11:40:08Z","timestamp":1775043608000},"source":"Crossref","is-referenced-by-count":0,"title":["Syphilis Diagnosis and Interest in Doxycycline Postexposure Prophylaxis Among Young Black Sexual and Gender Minorities"],"prefix":"10.1093","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7593-3022","authenticated-orcid":false,"given":"E","family":"Remund Wiger","sequence":"first","affiliation":[{"name":"Chicago Center for HIV Elimination, University of Chicago , Chicago, Illinois ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Almirol","sequence":"additional","affiliation":[{"name":"Chicago Center for HIV Elimination, University of Chicago , Chicago, Illinois ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M C","family":"Castro","sequence":"additional","affiliation":[{"name":"Chicago Center for HIV Elimination, University of Chicago , Chicago, Illinois ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6771-8138","authenticated-orcid":false,"given":"J","family":"Knox","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Columbia University, Mailman School of Public Health , NewYork, New York ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3422-4622","authenticated-orcid":false,"given":"Y T","family":"Chen","sequence":"additional","affiliation":[{"name":"Edward J. 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