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We present the first known pediatric case of Cache Valley virus encephalitis in an adolescent with IKZF1\/Ikaros immunodeficiency with viral clearance from cerebrospinal fluid after molnupiravir antiviral therapy.<\/jats:p>","DOI":"10.1093\/ofid\/ofag217","type":"journal-article","created":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T11:34:55Z","timestamp":1776339295000},"source":"Crossref","is-referenced-by-count":0,"title":["Molnupiravir Treatment Associated With Clearance of Cache Valley Virus From Cerebrospinal Fluid in an Immunocompromised Child With Meningoencephalitis"],"prefix":"10.1093","volume":"13","author":[{"given":"Destini Smith","family":"Byrd","sequence":"first","affiliation":[{"name":"Vanderbilt University Department of Pediatrics, , Nashville, Tennessee ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amitha","family":"Ananth","sequence":"additional","affiliation":[{"name":"University of Alabama at Birmingham Department of 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