{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T09:58:07Z","timestamp":1785491887134,"version":"3.56.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection (LRTI) in infants. Although influenza, parainfluenza, and human metapneumovirus also contribute to LRTI-related hospitalizations, their comparative population-level healthcare burden is not well defined. This study compared population-level healthcare utilization (HCU) associated with RSV-LRTI and LRTI caused by other respiratory viruses (ORspV-LRTI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This nationwide retrospective cohort study used electronic health records from Clalit Health Services (CHS), covering more than 5 million individuals in Israel. Infants born in 2015\u20132023 and hospitalized before 12 months of age with PCR-confirmed viral LRTI during the RSV season were included. Acute healthcare utilization (HCU) was assessed within 30 days following hospital discharge, and long-term respiratory HCU was evaluated through 6 years of age. HCU was expressed as population-level event rates per 100 000 live births during the study period, and incidence rate ratios (IRRs) were estimated using quasi-Poisson regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The cohort included 5822 infants (4951 RSV-LRTI; 871 ORspV-LRTI). RSV-LRTI infants were younger at hospitalization (median 2.7 vs 4.4 months; P &amp;lt; .001); Acute HCU was markedly higher in the RSV-LRTI group, including hospitalization duration (IRR = 6.90; 95% CI 4.07\u201312.6), and anti-asthma medications use (IRR = 4.77\u20138.04, P &amp;lt; .001 for all). Elevated HCU persisted long-term, with higher rates of respiratory medication use, pediatric pulmonologist visits (94.3 vs 16.3 per 100 000; IRR 6.44), and respiratory-related hospitalizations (IRR = 5.39) through 6 years of age. These findings remained consistent in subgroups of younger children and those who experienced more severe disease during the index bronchiolitis hospitalization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>RSV-associated LRTI in infancy is associated with substantially greater population-level HCU than LRTI caused by other respiratory viruses, both acutely and throughout early childhood, supporting prioritization of early-life RSV prevention strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ofid\/ofag402","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T22:36:43Z","timestamp":1782859003000},"source":"Crossref","is-referenced-by-count":0,"title":["Asthma-related Pediatric Healthcare Utilization after Hospitalization for RSV and Other Viral Lower Respiratory Tract Infections"],"prefix":"10.1093","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7372-6262","authenticated-orcid":false,"given":"Guy","family":"Hazan","sequence":"first","affiliation":[{"name":"Faculty of Health Sciences, Ben-Gurion University , Beer-Sheva ,","place":["Israel"]},{"name":"Pediatric Pulmonary Unit, Saban's Children Hospital, Soroka University Medical Center , Beer-Sheva ,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2276-521X","authenticated-orcid":false,"given":"Mai","family":"Ofri","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Ben-Gurion University , Beer-Sheva ,","place":["Israel"]},{"name":"Research and Innovation Center, Soroka University Medical Center , Beer-Sheva ,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lital","family":"Hertz","sequence":"additional","affiliation":[{"name":"Sanofi Israel Ltd, Vaccines 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