{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T09:58:07Z","timestamp":1785491887109,"version":"3.56.0"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Candida auris is an emerging fungal pathogen of global concern. Data on its epidemiology in the Middle East remain limited. We characterized the clinical profile, predictors, and outcomes of C. auris colonization among hospitalized patients in Saudi Arabia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective cohort study of 322 patients screened for C. auris between 2019 and 2025 at a tertiary care hospital in Riyadh. Patients were classified as C. auris positive (n = 107) or negative (n = 215). Baseline characteristics were compared using Mann\u2013Whitney U and Fisher's exact tests. Logistic regression identified predictors of positivity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The C. auris positivity rate was 33.2%, declining from 58.1% in 2021 to 24.8% in 2024 as surveillance expanded. Positive patients were older (median 70 vs 59 years, P &amp;lt; .001) and had longer hospital stays (median 124 vs 21 days, P &amp;lt; .001). Cardiovascular, endocrine, renal, and hematological comorbidities were significantly more prevalent. Age (per 10 years: odds ratio [OR] 1.26, 95% confidence interval [CI] 1.12\u20131.42) and length of stay (per 30 days: OR 1.20, 95% CI 1.12\u20131.28) were the strongest continuous predictors. All-cause in-hospital mortality was higher in positive patients (51.4% vs 25.1%; OR 3.15, 95% CI 1.90\u20135.23, P &amp;lt; .001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Candida auris\u2013positive patients exhibited advanced age, multimorbidity, prolonged hospitalization, and elevated all-cause mortality. These findings support targeted screening of high-risk populations in Gulf-region healthcare facilities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ofid\/ofag403","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T22:39:41Z","timestamp":1782859181000},"source":"Crossref","is-referenced-by-count":0,"title":["<i>Candida auris<\/i>\n                    Colonization in Hospitalized Patients at a Tertiary Care Center in Saudi Arabia: Clinical Characteristics, Predictors, and Outcomes"],"prefix":"10.1093","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5362-1228","authenticated-orcid":false,"given":"Abdullah A","family":"Awadh","sequence":"first","affiliation":[{"name":"College of Medicine, King Saud Bin Abdulaziz for Health Sciences , Jeddah ,","place":["Saudi Arabia"]},{"name":"King Abdulaziz Medical City, Ministry of National Guard-Health Affairs , Jeddah ,","place":["Saudi Arabia"]},{"name":"King Abdullah International Medical Research Center , Jeddah ,","place":["Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albaraa A","family":"Alsharif","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud Bin Abdulaziz for Health Sciences , Jeddah ,","place":["Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saad H","family":"Alahmari","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud Bin Abdulaziz for Health Sciences , Jeddah ,","place":["Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anmar A","family":"Bannani","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud Bin Abdulaziz for Health Sciences , Jeddah ,","place":["Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mazeed F","family":"Albogami","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud Bin Abdulaziz for Health Sciences , Jeddah ,","place":["Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assaf A","family":"Alzahrani","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud Bin Abdulaziz for Health Sciences , Jeddah ,","place":["Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulamajeed Y","family":"Ghazali","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud Bin Abdulaziz for Health Sciences , Jeddah ,","place":["Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,7,3]]},"reference":[{"key":"2026073105070524800_ofag403-B1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1348-0421.2008.00083.x","article-title":"Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese 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