{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T09:48:59Z","timestamp":1785923339549,"version":"3.56.0"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000030","name":"US Centers for Disease Control and Prevention","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Surveillance for serious fungal diseases (SFDs) relies on the capacity to recognize them and request and accurately perform diagnostic investigations. However, knowledge in resource-limited settings is suboptimal. This study evaluated the impact of a training intervention on the diagnosis and management of SFDs among clinicians and laboratory scientists in Nigerian tertiary hospitals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Clinicians in 6 hospitals were purposively selected and trained in 6 SFDs using standardized modules developed by international medical mycology experts. A quasi-experimental design assessed performance using a pretest and posttest. Designated laboratory scientists received hands-on training with pretraining and posttraining assessments. Paired t tests were used to assess differences in mean scores. An impact assessment of the laboratory mycology records was performed 1 year after intervention using analysis of variance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 149 clinicians and 8 laboratory scientists participated. Mean performance scores of participants improved significantly after training, with the following percentage increases: invasive aspergillosis (25.4%), chronic pulmonary aspergillosis (13.0%), invasive candidiasis (23.8%), Pneumocystis pneumonia (22.6%), mucormycosis (29.5%), and histoplasmosis (20.6%) (all P &amp;lt; .001). There was also a significant improvement in the laboratory scientists\u2019 posttraining performance (59.1%; P &amp;lt; .001). The laboratory mycology records reviewed 1 year later indicated a significant increase in the number of samples sent to the laboratory for mycological testing (P &amp;lt; .001) and the number and distribution of fungal isolates identified (P &amp;lt; .001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Training significantly improved SFD diagnosis and enhanced surveillance and patient care. Expanding this model across other low-resource settings is recommended.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ofid\/ofag442","type":"journal-article","created":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T11:40:03Z","timestamp":1784979603000},"source":"Crossref","is-referenced-by-count":0,"title":["Serious Fungal Diseases: Assessing the Impact of Training Clinicians and Laboratory Scientists in Nigeria"],"prefix":"10.1093","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1488-3345","authenticated-orcid":false,"given":"Rita","family":"Oladele","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos , Lagos ,","place":["Nigeria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1682-3733","authenticated-orcid":false,"given":"Damilola","family":"Akinlawon","sequence":"additional","affiliation":[{"name":"Department of Community Health and Primary Care, Lagos University Teaching Hospital , Lagos ,","place":["Nigeria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7834-866X","authenticated-orcid":false,"given":"Alexander","family":"Jordan","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention , Atlanta, Georgia ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8111-0743","authenticated-orcid":false,"given":"Iriagbonse","family":"Osaigbovo","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, College of Medical Sciences, University of Benin , Benin ,","place":["Nigeria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7785-0183","authenticated-orcid":false,"given":"Olufunmilola","family":"Makanjuola","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Parasitology, University of Ibadan , Ibadan ,","place":["Nigeria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7673-2414","authenticated-orcid":false,"given":"Ubong A","family":"Udoh","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Parasitology, University of Calabar , Calabar ,","place":["Nigeria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4111-8817","authenticated-orcid":false,"given":"Philip","family":"Nwajiobi-Princewill","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Parasitology, National Hospital , Abuja ,","place":["Nigeria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0075-9511","authenticated-orcid":false,"given":"Yahaya","family":"Mohammed","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Parasitology, College of Medical Sciences, Usmanu Danfodiyo University Teaching Hospital , Sokoto ,","place":["Nigeria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8671-4829","authenticated-orcid":false,"given":"Folake","family":"Peters","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Parasitology, Lagos University Teaching Hospital , Lagos ,","place":["Nigeria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2391-7770","authenticated-orcid":false,"given":"Tochi","family":"Okwor","sequence":"additional","affiliation":[{"name":"Nigeria Centre for Disease Control Antimicrobial Resistance\/Infection Prevention and Control Unit, , Abuja ,","place":["Nigeria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0788-9143","authenticated-orcid":false,"given":"Akin","family":"Osibogun","sequence":"additional","affiliation":[{"name":"Department of Community Health and Primary Care, College of Medicine University of Lagos , Lagos ,","place":["Nigeria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7734-685X","authenticated-orcid":false,"given":"Folasade","family":"Ogunsola","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos , Lagos ,","place":["Nigeria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1653-2824","authenticated-orcid":false,"given":"Martin","family":"Hoenigl","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine, Medical University of Graz , Graz ,","place":["Austria"]},{"name":"ECMM Excellence Center for Medical Mycology, Translational Medical Mycology Research Unit, Medical University of Graz , Graz ,","place":["Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4974-5607","authenticated-orcid":false,"given":"Jean-Pierre","family":"Gangneux","sequence":"additional","affiliation":[{"name":"Centre National de R\u00e9f\u00e9rence des Mycoses et Antifongiques LA-AspC Aspergilloses Chroniques, European Excellence Center for Medical Mycology (ECMM EC), Centre Hospitalier Universitaire de Rennes , Rennes ,","place":["France"]},{"name":"IRSET (Institut de Recherche en Sant\u00e9, Environnement et Travail), UMR_S 1085, Inserm, Universit\u00e9 de Rennes, CHU Rennes, \u00c9cole des Hautes \u00c9tudes en Sant\u00e9 Publique (EHESP), Rennes ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4383-5994","authenticated-orcid":false,"given":"Shawn R","family":"Lockhart","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention , Atlanta, Georgia ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2251-8033","authenticated-orcid":false,"given":"Tom","family":"Chiller","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention , Atlanta, Georgia ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3777-9500","authenticated-orcid":false,"given":"Nancy A","family":"Chow","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention , Atlanta, Georgia ,","place":["USA"]},{"name":"The members of Nigeria Fungal Diseases Surveillance and Capacity Building (NIFUSCAB) program are listed in the Supplementary Data"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,7,29]]},"reference":[{"key":"2026080505420056700_ofag442-B1","volume-title":"WHO fungal priority pathogens list to guide research, development and public health action","author":"World Health 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