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We describe a series of 19 CDC cases in which plasma microbial cell-free DNA sequencing was performed due to diagnostic uncertainty. Results influenced antifungal management in most cases.<\/jats:p>","DOI":"10.1093\/ofid\/ofag543","type":"journal-article","created":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T11:40:53Z","timestamp":1788522053000},"source":"Crossref","is-referenced-by-count":0,"title":["Plasma Microbial Cell-Free DNA Sequencing for the Diagnosis of Chronic Disseminated Candidiasis in Patients with Hematologic Malignancies"],"prefix":"10.1093","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9073-1258","authenticated-orcid":false,"given":"Alejandro","family":"De La Hoz","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Brigham and Women's Hospital , Boston, Massachusetts ,","place":["USA"]},{"name":"Division of Infectious Diseases, Massachusetts General Hospital , Boston, Massachusetts ,","place":["USA"]},{"name":"Department of Medicine, Harvard Medical School , Boston, Massachusetts 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C","family":"Issa","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Brigham and Women's Hospital , Boston, Massachusetts ,","place":["USA"]},{"name":"Department of Medicine, Harvard Medical School , Boston, Massachusetts ,","place":["USA"]},{"name":"Dana-Farber Cancer Institute Division of Infectious Diseases, , Boston, Massachusetts ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyssa","family":"Letourneau","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Massachusetts General Hospital , Boston, Massachusetts ,","place":["USA"]},{"name":"Department of Medicine, Harvard Medical School , Boston, Massachusetts ,","place":["USA"]},{"name":"Mass General Cancer Center Division of Infectious Diseases, , Boston, Massachusetts ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsey R","family":"Baden","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Brigham and Women's Hospital , Boston, Massachusetts ,","place":["USA"]},{"name":"Department of Medicine, Harvard Medical School , Boston, Massachusetts ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4271-7443","authenticated-orcid":false,"given":"Sarah P","family":"Hammond","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Massachusetts General Hospital , Boston, Massachusetts ,","place":["USA"]},{"name":"Department of Medicine, Harvard Medical School , Boston, Massachusetts ,","place":["USA"]},{"name":"Mass General Cancer Center Division of Infectious Diseases, , Boston, Massachusetts ,","place":["USA"]},{"name":"Dana-Farber Cancer Institute Division of Infectious Diseases, , Boston, Massachusetts ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8093-5647","authenticated-orcid":false,"given":"Jessica 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