{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T08:48:06Z","timestamp":1792399686506,"version":"4.4.0"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"10","funder":[{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["75D30123F00002"],"award-info":[{"award-number":["75D30123F00002"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["75D30124F00003"],"award-info":[{"award-number":["75D30124F00003"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007268","name":"Washington University in St Louis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007268","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Oseltamivir is an antiviral medication for influenza that can reduce the duration of symptoms and may lower the risk of some complications. Recommendations for use of oseltamivir include in the outpatient setting for individuals at higher risk of developing influenza complications. The objectives of the current study were to describe oseltamivir initiation and treatment completion among influenza-positive outpatients and identify factors associated with each.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In a US outpatient household transmission study, index participants with laboratory-confirmed influenza provided up to 12 days of detailed information on medication use. We described oseltamivir initiation among index case patients and treatment course completion of \u226510 doses among patients who started oseltamivir. We used adjusted logistic regression to identify factors associated with initiation and course completion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 823 enrolled index patients, 324 (39%) initiated oseltamivir treatment. Of 406 persons at higher risk for influenza complications, 172 (42%) initiated treatment. Oseltamivir initiation was lowest among children aged 2\u20134 years (19%), compared with all other age groups. After exclusion of the likely censored cases, 133 of 313 patients (42%) completed the recommended treatment course. Among 163 individuals at higher risk of influenza complications, 69 (42%) completed the recommended treatment course. Children &amp;lt;2 years old were significantly less likely to complete treatment than adults aged 18\u201350 years (adjusted odds ratio, 0.21 [95% confidence interval, .04\u2013.78; P = .03); the reasons for discontinuation could not be determined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this population in the outpatient setting, fewer than half of persons at higher risk for influenza complications initiated oseltamivir treatment, and fewer than half of those who initiated treated completed it.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ofid\/ofag587","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T19:32:53Z","timestamp":1789673573000},"source":"Crossref","is-referenced-by-count":0,"title":["Characterizing Oseltamivir Use Among Community-Dwelling Patients Diagnosed With Influenza Virus Infection, 2023\u20132025"],"prefix":"10.1093","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-5642-9694","authenticated-orcid":false,"given":"Emily A","family":"McNair","sequence":"first","affiliation":[{"name":"STI Federal , Sault Ste Marie, Michigan ,","place":["USA"]},{"name":"Influenza Division, Centers for Disease Control and Prevention , Atlanta, Georgia ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennie H","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Medicine, Northwestern University Feinberg School of Medicine , Chicago, Illinois ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos G","family":"Grijalva","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center , Nashville, Tennessee ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9947-588X","authenticated-orcid":false,"given":"Son H","family":"McLaren","sequence":"additional","affiliation":[{"name":"New York-Presbyterian Hospital , New York, New York ,","place":["USA"]},{"name":"Department of Emergency Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center , New York, New York ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6702-8698","authenticated-orcid":false,"given":"Jessica E","family":"Biddle","sequence":"additional","affiliation":[{"name":"Influenza Division, Centers for Disease Control and Prevention , Atlanta, Georgia ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Dean","sequence":"additional","affiliation":[{"name":"Influenza Division, Centers for Disease Control and Prevention , Atlanta, Georgia ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8208-9971","authenticated-orcid":false,"given":"Lydia","family":"Bristol","sequence":"additional","affiliation":[{"name":"Influenza Division, Centers for Disease Control and Prevention , Atlanta, Georgia ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9242-3507","authenticated-orcid":false,"given":"Elizabeth B","family":"White","sequence":"additional","affiliation":[{"name":"Influenza Division, Centers for Disease Control and Prevention , Atlanta, Georgia ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8602-5879","authenticated-orcid":false,"given":"Stephanie A","family":"Fritz","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine , St. Louis, Missouri ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5469-0727","authenticated-orcid":false,"given":"Rachel M","family":"Presti","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine , St. Louis, Missouri ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline A","family":"O\u2019Neil","sequence":"additional","affiliation":[{"name":"Department of Medicine, Northwestern University Feinberg School of Medicine , Chicago, Illinois ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen","family":"Sano","sequence":"additional","affiliation":[{"name":"New York-Presbyterian Hospital , New York, New York ,","place":["USA"]},{"name":"Department of Emergency Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center , New York, New York ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celibell","family":"Vargas","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center , New York, New York ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Schmitz","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center , Nashville, Tennessee ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9849-1634","authenticated-orcid":false,"given":"Yuwei","family":"Zhu","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center , Nashville, Tennessee ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1832-7020","authenticated-orcid":false,"given":"Theresa A","family":"Scott","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center , Nashville, Tennessee ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacey","family":"House","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine , St. Louis, Missouri ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H Keipp","family":"Talbot","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center , Nashville, Tennessee ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2113-7247","authenticated-orcid":false,"given":"Melissa S","family":"Stockwell","sequence":"additional","affiliation":[{"name":"New York-Presbyterian Hospital , New York, New York ,","place":["USA"]},{"name":"Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center , New York, New York ,","place":["USA"]},{"name":"Department of Population and Family Health, Mailman School of Public Health, Columbia University Irving Medical Center , New York, New York ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra M","family":"Mellis","sequence":"additional","affiliation":[{"name":"Influenza Division, Centers for Disease Control and Prevention , Atlanta, Georgia ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,9,21]]},"reference":[{"key":"2026101904315578400_ofag587-B1","author":"Centers for Disease Control and Prevention"},{"key":"2026101904315578400_ofag587-B2","author":"Centers for Disease Control and Prevention"},{"key":"2026101904315578400_ofag587-B3","article-title":"Recommendations for prevention and control of influenza in children, 2025-2026: policy statement","volume":"156","author":"Committee on Infectious 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