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The patient presented with an acute febrile mononucleosis-like illness after increasing nonadherence to antiretroviral therapy. A marked increase in HIV RNA level of 1 220 000 copies\/mL from less than 20 copies\/mL occurred within 3 weeks. The diagnosis of acute HIV syndrome was made after alternative causes of illness were ruled out.<\/jats:p>","DOI":"10.1093\/ofid\/ofu112","type":"journal-article","created":{"date-parts":[[2014,12,9]],"date-time":"2014-12-09T03:11:31Z","timestamp":1418094691000},"source":"Crossref","is-referenced-by-count":2,"title":["Acute Human Immunodeficiency Virus (HIV) Syndrome After Nonadherence to Antiretroviral Therapy in a Patient With Chronic HIV Infection: A Case Report"],"prefix":"10.1093","volume":"1","author":[{"given":"Seong K.","family":"Choi","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Cedars-Sinai Medical Center, Los Angeles, California"},{"name":"Infectious Diseases Section, VA Greater Los Angeles Healthcare System, California"},{"name":"David Geffen School of Medicine at the University of California, Los Angeles"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher J.","family":"Graber","sequence":"additional","affiliation":[{"name":"Infectious Diseases Section, VA Greater Los Angeles Healthcare System, California"},{"name":"David Geffen School of Medicine at the University of California, Los Angeles"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2014,12,23]]},"reference":[{"key":"2020081009564491300_OFU112C1","doi-asserted-by":"crossref","first-page":"827","DOI":"10.7326\/0003-4819-128-10-199805150-00005","article-title":"Acute HIV syndrome after discontinuation of antiretroviral therapy in a patient treated before seroconversion","volume":"128","author":"Daar","year":"1998","journal-title":"Ann Intern Med"},{"key":"2020081009564491300_OFU112C2","doi-asserted-by":"crossref","first-page":"435","DOI":"10.7326\/0003-4819-133-6-200009190-00011","article-title":"Recurrence of the acute HIV syndrome after interruption of antiretroviral therapy in a patient with chronic HIV infection: a case report","volume":"133","author":"Kilby","year":"2000","journal-title":"Ann Intern Med"},{"key":"2020081009564491300_OFU112C3","doi-asserted-by":"crossref","first-page":"430","DOI":"10.7326\/0003-4819-133-6-200009190-00010","article-title":"Retroviral rebound syndrome after cessation of suppressive antiretroviral therapy in three patients with chronic HIV infection","volume":"133","author":"Colven","year":"2000","journal-title":"Ann Intern Med"},{"key":"2020081009564491300_OFU112C4","doi-asserted-by":"crossref","first-page":"e43754","DOI":"10.1371\/journal.pone.0043754","article-title":"Plasma HIV viral rebound following protocol-indicated cessation of ART commenced in primary and chronic HIV infection","volume":"7","author":"Hamlyn","year":"2012","journal-title":"PloS One"},{"key":"2020081009564491300_OFU112C5","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1086\/512681","article-title":"Interruption of antiretroviral treatment in HIV-infected patients with preserved immune function is associated with a low rate of clinical progression: a prospective study by AIDS Clinical Trials Group 5170","volume":"195","author":"Skiest","year":"2007","journal-title":"J Infect Dis"}],"container-title":["Open Forum Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ofid\/article-pdf\/1\/3\/ofu112\/33621723\/ofu112.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ofid\/article-pdf\/1\/3\/ofu112\/33621723\/ofu112.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,10]],"date-time":"2020-08-10T14:15:15Z","timestamp":1597068915000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ofid\/article\/doi\/10.1093\/ofid\/ofu112\/1400864"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":5,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ofid\/ofu112","relation":{},"ISSN":["2328-8957"],"issn-type":[{"type":"electronic","value":"2328-8957"}],"subject":[],"published-other":{"date-parts":[[2014]]},"published":{"date-parts":[[2014]]},"article-number":"ofu112"}}