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Using data from a multicohort database (Injecting Cohorts [InC3] Collaborative), we establish an independent association between host IFNL4 genotype and symptoms of acute hepatitis C virus infection. This association potentially explains the higher spontaneous clearance observed in some patients with symptomatic disease.<\/jats:p>","DOI":"10.1093\/ofid\/ofw024","type":"journal-article","created":{"date-parts":[[2016,2,9]],"date-time":"2016-02-09T01:08:43Z","timestamp":1454980123000},"source":"Crossref","is-referenced-by-count":2,"title":["Interferon Lambda 4 Genotype Is Associated With Jaundice and Elevated Aminotransferase Levels During Acute Hepatitis C Virus Infection: Findings From the InC3 Collaborative"],"prefix":"10.1093","volume":"3","author":[{"given":"Kimberly","family":"Page","sequence":"first","affiliation":[{"name":"Division of Epidemiology, Biostatistics and Preventive Medicine, University ofNew Mexico Health Sciences Center, Albuquerque, New Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Mirzazadeh","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, University of California San 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