{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T14:59:01Z","timestamp":1761663541136,"version":"3.41.2"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2016,11,25]],"date-time":"2016-11-25T00:00:00Z","timestamp":1480032000000},"content-version":"vor","delay-in-days":329,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Background. \u2003Despite the low and decreasing prevalence of tuberculosis (TB) in the United States, there remain certain high-risk groups with high incidence rates. The targeted screening and treatment of latent TB infection (LTBI) among these high-risk groups are needed to achieve TB elimination; however, by most accounts, LTBI treatment completion rates remain low.<\/jats:p>\n               <jats:p>Methods. \u2003We retrospectively studied all patients accepting treatment for LTBI at the Fulton County Health Department TB clinic over 2 years. Medical chart abstraction was performed to collect information on sociodemographics, medical, and LTBI treatment history. Treatment completion was defined as finishing \u226588% of the prescribed regimen. Logistic regression analysis was performed to identify predictors of treatment completion.<\/jats:p>\n               <jats:p>Results. \u2003Among 547 adults offered LTBI treatment, 424 (78%) accepted treatment and 298 of 424 (70%) completed treatment. The median age was 42 years, most patients were black (77%), and close to one third did not have stable housing. No significant difference in completion rates was found between the 3 regimens of 9 months isoniazid (65%), 4 months rifampin (71%), and 3 months of weekly rifapentine and isoniazid (79%). In multivariate analysis, having stable housing increased the odds of finishing treatment, whereas tobacco use and an adverse event decreased the odds.<\/jats:p>\n               <jats:p>Conclusion. \u2003Utilizing comprehensive case management, we demonstrated high rates of LTBI treatment completion, including among those receiving a 3-month regimen. Completion rates were higher among persons with stable housing, and this finding highlights the need to develop strategies that will improve adherence among homeless persons.<\/jats:p>","DOI":"10.1093\/ofid\/ofw082","type":"journal-article","created":{"date-parts":[[2016,10,14]],"date-time":"2016-10-14T03:05:21Z","timestamp":1476414321000},"source":"Crossref","is-referenced-by-count":17,"title":["Predictors of Latent Tuberculosis Infection Treatment After Introduction of a New Regimen: A Retrospective Cohort Study at an Inner City Clinic"],"prefix":"10.1093","volume":"3","author":[{"given":"Aliya","family":"Yamin","sequence":"first","affiliation":[{"name":"Fulton County Health Department, Atlanta, Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ethan","family":"Bornstein","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine, Atlanta, Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Hensel","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine, Atlanta, Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Fulton County Health Department, Atlanta, Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Russell R.","family":"Kempker","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine, Atlanta, Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2016,4,21]]},"reference":[{"key":"2020081006163176300_OFW082C1","first-page":"265","article-title":"Tuberculosis trends--United States, 2014","volume":"64","author":"Scott","year":"2015","journal-title":"MMWR Morb Mortal Wkly Rep"},{"author":"World Health Organization","article-title":"Global tuberculosis 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