{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T16:25:55Z","timestamp":1782923155709,"version":"3.54.5"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2017,3,27]],"date-time":"2017-03-27T00:00:00Z","timestamp":1490572800000},"content-version":"vor","delay-in-days":85,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Pyogenic arthritis of the small joints of the hand and wrist is a known but poorly described entity. The objective of this work was to characterize the clinical presentation, antimicrobial treatment, and surgical interventions of native small joint arthritis (SJA) treated in our tertiary center.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>According to predefined variables, medical records of adult patients with SJA treated in a Swiss university hospital between 2005 and 2013 were retrospectively analyzed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The median age of 97 patients (101 joints) was 52 years (interquartile range [IQR], 38\u201368 years); 52% had no comorbidity. Small joint arthritis of the second and third fingers accounted for 53% of infections, with metacarpal-phalangeal and proximal interphalangeal joints most commonly involved. Of 86 (89%) episodes with an exogenous source, 63 (65%) followed a trauma. The most commonly isolated microorganism was Staphylococcus aureus (38%), followed by \u03b2-hemolytic streptococci (13%) and Pasteurella spp (11%). Eighty-seven episodes (89 joints) in patients with follow-up examinations were included in treatment and outcome analyses. Up to 2 surgical interventions were required to cure infection in 74 (83%) joints. Median antimicrobial treatment duration was 14 days (IQR, 12\u201328 days), with amoxicillin\/clavulanate administered in 74 (85%) episodes. At follow up, cure of infection was noted in all episodes and good functional outcome in 79% of episodes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Small joint arthritis shows considerable differences from clinical patterns reported for larger joints. In our series, the outcome was good with no more than 2 surgical interventions and median treatment duration of 14 days in 79% of episodes.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ofid\/ofx058","type":"journal-article","created":{"date-parts":[[2017,3,25]],"date-time":"2017-03-25T13:56:23Z","timestamp":1490450183000},"source":"Crossref","is-referenced-by-count":31,"title":["Pyogenic Arthritis of the Fingers and the Wrist: Can We Shorten Antimicrobial Treatment Duration?"],"prefix":"10.1093","volume":"4","author":[{"given":"Rahel","family":"Meier","sequence":"first","affiliation":[{"name":"Departments of Plastic and Hand Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Wirth","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Inselgruppe Aarberg, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederik","family":"Hahn","sequence":"additional","affiliation":[{"name":"Division of Hand Surgery, Department of Orthopedics, University of Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"V\u00f6gelin","sequence":"additional","affiliation":[{"name":"Departments of Plastic and Hand Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parham","family":"Sendi","sequence":"additional","affiliation":[{"name":"Infectious Diseases, Inselspital, Bern University Hospital and"},{"name":"Institute of Infectious Diseases, University of Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,3,25]]},"reference":[{"key":"2020081005073655100_CIT0001","first-page":"11","article-title":"Pyogenic arthritis in adults","volume":"67","author":"Dubost","year":"2000","journal-title":"Joint Bone Spine"},{"key":"2020081005073655100_CIT0002","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.3899\/jrheum.150434","article-title":"Native joint septic arthritis: epidemiology, clinical features, and microbiological causes in a New Zealand population","volume":"42","author":"Kennedy","year":"2015","journal-title":"J Rheumatol"},{"key":"2020081005073655100_CIT0003","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/s15010-013-0566-0","article-title":"Antimicrobial management of septic arthritis of the hand and wrist","volume":"42","author":"Kowalski","year":"2014","journal-title":"Infection"},{"key":"2020081005073655100_CIT0004","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1055\/s-2007-965137","article-title":"[Septic arthritis of finger joints]","volume":"39","author":"Angly","year":"2007","journal-title":"Handchir Mikrochir Plast Chir"},{"key":"2020081005073655100_CIT0005","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1097\/00000637-200212000-00012","article-title":"Surgical infections of the hand and upper extremity: a county hospital experience","volume":"49","author":"Weinzweig","year":"2002","journal-title":"Ann Plast Surg"},{"key":"2020081005073655100_CIT0006","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1093\/cid\/cis803","article-title":"Diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America","volume":"56","author":"Osmon","year":"2013","journal-title":"Clin Infect Dis"},{"key":"2020081005073655100_CIT0007","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1016\/j.jhsa.2014.03.031","article-title":"Acute hand infections","volume":"39","author":"Osterman","year":"2014","journal-title":"J Hand Surg Am"},{"key":"2020081005073655100_CIT0008","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/J.JHSB.2006.08.011","article-title":"Septic arthritis of the small joints of the hand","volume":"31","author":"Sinha","year":"2006","journal-title":"J Hand Surg Br"},{"key":"2020081005073655100_CIT0009","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/S0753-9053(82)80004-5","article-title":"Acute septic arthritis of the fingers. A clinical study of 87 cases","volume":"1","author":"Richard","year":"1982","journal-title":"Ann Chir Main"},{"key":"2020081005073655100_CIT0010","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1097\/00000637-199906000-00007","article-title":"Septic arthritis of the metacarpophalangeal and interphalangeal joints of the hand","volume":"42","author":"Boustred","year":"1999","journal-title":"Ann Plast Surg"},{"key":"2020081005073655100_CIT0011","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1111\/j.1553-2712.2011.01121.x","article-title":"Evidence-based diagnostics: adult septic arthritis","volume":"18","author":"Carpenter","year":"2011","journal-title":"Acad Emerg Med"},{"key":"2020081005073655100_CIT0012","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.jbspin.2014.05.001","article-title":"Three-decade trends in the distribution of organisms causing septic arthritis in native joints: single-center study of 374 cases","volume":"81","author":"Dubost","year":"2014","journal-title":"Joint Bone Spine"},{"key":"2020081005073655100_CIT0013","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1136\/ard.2007.077131","article-title":"Septic arthritis in Iceland 1990\u20132002: increasing incidence due to iatrogenic infections","volume":"67","author":"Geirsson","year":"2008","journal-title":"Ann Rheum Dis"},{"key":"2020081005073655100_CIT0014","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1128\/CMR.15.4.527-544.2002","article-title":"Acute septic arthritis","volume":"15","author":"Shirtliff","year":"2002","journal-title":"Clin Microbiol Rev"},{"key":"2020081005073655100_CIT0015","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s00068-007-6183-9","article-title":"Hand trauma pitfalls: a retrospective study of fight bites","volume":"34","author":"Goon","year":"2008","journal-title":"Eur J Trauma Emerg Surg"},{"key":"2020081005073655100_CIT0016","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1055\/s-2003-39097","article-title":"Diagnosis and treatment of bites by cats, dogs and humans","volume":"128","author":"Vogt","year":"2003","journal-title":"Dtsch Med Wochenschr"},{"key":"2020081005073655100_CIT0017","doi-asserted-by":"crossref","first-page":"330","DOI":"10.3109\/2000656X.2014.886581","article-title":"Treatment of open hand injuries: does timing of surgery matter? A single-centre prospective analysis","volume":"48","author":"Juon","year":"2014","journal-title":"J Plast Surg Hand Surg"},{"key":"2020081005073655100_CIT0018","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.jinf.2015.08.002","article-title":"Administration of antibiotic agents before intraoperative sampling in orthopedic infections alters culture results","volume":"71","author":"Al-Mayahi","year":"2015","journal-title":"J Infect"},{"key":"2020081005073655100_CIT0019","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/S0140-6736(09)61595-6","article-title":"Bacterial septic arthritis in adults","volume":"375","author":"Mathews","year":"2010","journal-title":"Lancet"}],"container-title":["Open Forum Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ofid\/article-pdf\/4\/2\/ofx058\/33602771\/ofx058.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ofid\/article-pdf\/4\/2\/ofx058\/33602771\/ofx058.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,10]],"date-time":"2020-08-10T09:09:42Z","timestamp":1597050582000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ofid\/article\/doi\/10.1093\/ofid\/ofx058\/3090339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,4,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ofid\/ofx058","relation":{},"ISSN":["2328-8957"],"issn-type":[{"value":"2328-8957","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017]]},"published":{"date-parts":[[2017]]},"article-number":"ofx058"}}