{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:13:14Z","timestamp":1753877594776,"version":"3.41.2"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"3","funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Enterohepatic Helicobacter-like organisms (HLO) have been recognized as causes of human infection since 1984, primarily as a cause of bacteremia and cellulitis in immunocompromised individuals, but the spectrum of illness due to HLO has expanded based on numerous reports from Japan.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We report 4 epidemiologically unrelated immunocompetent patients with HLO bacteremia diagnosed within a 2-year period. Three patients had cellulitis and 1 patient had unexplained fever. 16S ribosomal deoxyribonucleic acid (rDNA) sequence analysis of 2 isolates suggested that they were Helicobacter cinaedi, and whole-genome sequencing showed that they differed only slightly from reference strains.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>We believe that this syndrome is more common than reported, but it is easily overlooked because the skin lesions resemble streptococcal cellulitis and respond very rapidly to \u03b2-lactam antibiotics, and the organism is difficult to isolate from the blood. All HLO in our series were isolated from blood using the ESP system and were not detected in 2 other widely used commercial blood culture systems.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ofid\/ofx074","type":"journal-article","created":{"date-parts":[[2017,8,3]],"date-time":"2017-08-03T17:57:58Z","timestamp":1501783078000},"source":"Crossref","is-referenced-by-count":1,"title":["Bacteremia and Skin Infections in Four Patients Caused by\n            Helicobacter-Like Organisms"],"prefix":"10.1093","volume":"4","author":[{"given":"Josu\u00e9","family":"P\u00e9rez-Santiago","sequence":"first","affiliation":[{"name":"Department of Medicine, University of California San Diego, La Jolla"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Ramirez-Gaona","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics, University of Alberta, Edmonton, Canada; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Holm-Kennedy","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California San Diego, La Jolla"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davey M","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California San Diego, La Jolla"},{"name":"Veterans Affairs Healthcare Systems, San Diego, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Fierer","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California San Diego, La Jolla"},{"name":"Veterans Affairs Healthcare Systems, San Diego, 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