{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T22:05:31Z","timestamp":1761948331315,"version":"3.41.2"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2017,11,24]],"date-time":"2017-11-24T00:00:00Z","timestamp":1511481600000},"content-version":"vor","delay-in-days":327,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UL1TR000454"],"award-info":[{"award-number":["UL1TR000454"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A patient who never resided in an endemic area for dimorphic fungi was diagnosed with Histoplasma capsulatum endocarditis. His diagnosis was suggested by yeast and hyphae on cardiac valve tissue pathology. Isavuconazole was an optimal therapeutic option due to renal dysfunction and anticoagulation with warfarin for mechanical valve replacement.<\/jats:p>","DOI":"10.1093\/ofid\/ofx241","type":"journal-article","created":{"date-parts":[[2017,11,24]],"date-time":"2017-11-24T09:16:11Z","timestamp":1511514971000},"source":"Crossref","is-referenced-by-count":12,"title":["Diagnostic Importance of Hyphae on Heart Valve Tissue in Histoplasma Endocarditis and Treatment With Isavuconazole"],"prefix":"10.1093","volume":"4","author":[{"given":"Zanthia","family":"Wiley","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael H","family":"Woodworth","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesse T","family":"Jacob","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shawn R","family":"Lockhart","sequence":"additional","affiliation":[{"name":"Fungal Reference Laboratory Mycotic Diseases Branch Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadine G","family":"Rouphael","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan C","family":"Gullett","sequence":"additional","affiliation":[{"name":"Microbiology, Southern California Permanente Medical Group Regional Reference Laboratories, Greater Los Angeles Area, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeannette","family":"Guarner","sequence":"additional","affiliation":[{"name":"Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberly","family":"Workowski","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2017,11,24]]},"reference":[{"key":"2020081005374173800_CIT0001","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/ofid\/ofw194.33","article-title":"Multistate epidemiologic description of histoplasmosis in the United States, 2004\u20132015","volume":"3","author":"Armstrong","year":"2016","journal-title":"Open Forum Infect Dis"},{"key":"2020081005374173800_CIT0002","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.3201\/eid2111.141950","article-title":"Mycotic infections acquired outside areas of known endemicity, United States","volume":"21","author":"Benedict","year":"2015","journal-title":"Emerg Infect Dis"},{"key":"2020081005374173800_CIT0003","doi-asserted-by":"crossref","first-page":"K21","DOI":"10.1530\/ERP-14-0103","article-title":"Severe pulmonic valve regurgitation due to histoplasma endocarditis","volume":"2","author":"Konik","year":"2015","journal-title":"Echo Res Pract"},{"key":"2020081005374173800_CIT0004","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1097\/MD.0000000000000034","article-title":"Histoplasma capsulatum endocarditis: multicenter case series with review of current diagnostic techniques and treatment","volume":"93","author":"Riddell","year":"2014","journal-title":"Medicine"},{"key":"2020081005374173800_CIT0005","first-page":"330","article-title":"Hyphal forms of Histoplasma capsulatum. 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