{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T09:03:46Z","timestamp":1789981426394,"version":"4.0.1"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2018,4,7]],"date-time":"2018-04-07T00:00:00Z","timestamp":1523059200000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>To investigate to what extent asymptomatic vs symptomatic prenatal Zika virus infections contribute to birth defects, we identified 3 prospective and 8 retrospective studies. The ratio varied greatly in the retrospective studies, most likely due to recruitment and recall bias. The prospective studies revealed a ratio of 1:1 for asymptomatic vs symptomatic maternal Zika infections resulting in adverse fetal outcomes.<\/jats:p>","DOI":"10.1093\/ofid\/ofy073","type":"journal-article","created":{"date-parts":[[2018,4,7]],"date-time":"2018-04-07T08:13:46Z","timestamp":1523088826000},"source":"Crossref","is-referenced-by-count":36,"title":["Asymptomatic Prenatal Zika Virus Infection and Congenital Zika Syndrome"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4797-908X","authenticated-orcid":false,"given":"Enny S","family":"Paixao","sequence":"first","affiliation":[{"name":"Infectious Disease Epidemiology and Department of Disease Control, London School of Hygiene and Tropical Medicine, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Yee","family":"Leong","sequence":"additional","affiliation":[{"name":"Lee Kong Chian School of Medicine, Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura C","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Infectious Disease Epidemiology and Department of Disease Control, London School of Hygiene and Tropical Medicine, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annelies","family":"Wilder-Smith","sequence":"additional","affiliation":[{"name":"Infectious Disease Epidemiology and Department of Disease Control, London School of Hygiene and Tropical Medicine, London, UK"},{"name":"Lee Kong Chian School of Medicine, Singapore, Singapore"},{"name":"Department of Public Health and Clinical Medicine, Umea University, Umea, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,4,7]]},"reference":[{"key":"2020081004280001000_CIT0001","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1056\/NEJMsr1604338","article-title":"Zika virus and birth 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