{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:14:15Z","timestamp":1753877655383,"version":"3.41.2"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2019,2,11]],"date-time":"2019-02-11T00:00:00Z","timestamp":1549843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Sharpe-Strumia Research Foundation of the Bryn Mawr Hospital","award":["SSRF2017-05","SSRF2018-03"],"award-info":[{"award-number":["SSRF2017-05","SSRF2018-03"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Tick-borne illnesses are increasing but are often underreported. Few cases of babesiosis have been reported from Pennsylvania. Our 4-hospital system in southeastern Pennsylvania saw a rise in cases from 7 or fewer yearly in 2008\u20132014 to 26 cases in 2015. There appear to be multiple potential causes of this increase in frequency.<\/jats:p>","DOI":"10.1093\/ofid\/ofz066","type":"journal-article","created":{"date-parts":[[2019,2,11]],"date-time":"2019-02-11T15:19:05Z","timestamp":1549898345000},"source":"Crossref","is-referenced-by-count":7,"title":["Increasing Babesiosis in Southeastern Pennsylvania, 2008\u20132017"],"prefix":"10.1093","volume":"6","author":[{"given":"Hans H","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Medicine, Main Line Health System, Bryn Mawr, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Cushinotto","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Main Line Health System, Bryn Mawr, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olarae","family":"Giger","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Main Line Health System, Bryn Mawr, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary","family":"Daum","sequence":"additional","affiliation":[{"name":"Department of Pathology, Main Line Health System, Bryn Mawr, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"McBride","sequence":"additional","affiliation":[{"name":"Department of Infection Prevention, Main Line Health System, Bryn Mawr, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth A","family":"Negron","sequence":"additional","affiliation":[{"name":"Pennsylvania Department of Health, Harrisburg, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kurt","family":"Vandegrift","sequence":"additional","affiliation":[{"name":"Department of Biology, Pennsylvania State University, State College, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciano","family":"Kapelusznik","sequence":"additional","affiliation":[{"name":"Department of Medicine, Main Line Health System, Bryn Mawr, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,2,11]]},"reference":[{"key":"2020081003473500400_CIT0001","doi-asserted-by":"crossref","first-page":"496","DOI":"10.15585\/mmwr.mm6717e1","article-title":"Vital signs: trends in reported vectorborne diseases cases \u2013 United States and Territories, 2004\u20132016","volume":"67","author":"Rosenberg","year":"2018","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2020081003473500400_CIT0002","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1056\/NEJMra1202018","article-title":"Human babesiosis","volume":"366","author":"Vannier","year":"2012","journal-title":"New Eng J Med"},{"key":"2020081003473500400_CIT0003","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.pt.2015.09.008","article-title":"Coinfection by Ixodes tick-borne pathogens: ecological, epidemiological, and clinical consequences","volume":"32","author":"Diuk-Wasser","year":"2016","journal-title":"Trends Parasitol"},{"key":"2020081003473500400_CIT0004","doi-asserted-by":"crossref","first-page":"e115494","DOI":"10.1371\/journal.pone.0115494","article-title":"Borrelia burgdorferi promotes the establishment of Babesia microti in the Northeastern United States","volume":"9","author":"Dunn","year":"2014","journal-title":"PLoS One"},{"key":"2020081003473500400_CIT0005","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3201\/eid2002.130644","article-title":"Monitoring human babesiosis emergence through vector surveillance, New England, USA","volume":"20","author":"Diuk-Wasser","year":"2014","journal-title":"Emerg Infect Dis"},{"key":"2020081003473500400_CIT0006","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1186\/s13071-014-0553-z","article-title":"Comparison of phenology and pathogen prevalence, including infection with the Ehrlichia muris-like (EML) agent, of Ixodes scapularis removed from soldiers in the Midwestern and the Northeastern United States over a 15 year period (1997\u20132012)","volume":"7","author":"Stromdahl","year":"2014","journal-title":"J Parasit Vectors"},{"key":"2020081003473500400_CIT0007","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1093\/jme\/tjv037","article-title":"Prevalence rates of Borrelia burgdorferi (Spirochaetales: Spirochaetaceae), Anaplasma phagocytophilum (Rickettsiales: Anaplasmataceae), and Babesia microti (Piroplasmida: Babesiidae) in host-seeking Ixodes scapularis (Acari: Ixodidae) from Pennsylvania","volume":"52","author":"Hutchinson","year":"2015","journal-title":"J Med Entomol"},{"key":"2020081003473500400_CIT0008","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.3201\/eid1907.121593","article-title":"Babesia microti infection, Eastern Pennsylvania, USA","volume":"19","author":"Acosta","year":"2013","journal-title":"Emerg Infect Dis"},{"key":"2020081003473500400_CIT0009","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.4269\/ajtmh.17-0146","article-title":"Risk factors for severe infection, hospitalization, and prolonged antimicrobial therapy in patients with babesiosis","volume":"97","author":"Mareedu","year":"2017","journal-title":"Am J Trop Med Hyg"},{"key":"2020081003473500400_CIT0010"},{"key":"2020081003473500400_CIT0011","doi-asserted-by":"crossref","first-page":"e0193837","DOI":"10.1371\/journal.pone.0193837","article-title":"Zoonotic Babesia microti in the Northeastern U.S.: evidence for the expansion of a specific parasite lineage","volume":"13","author":"Goethert","year":"2018","journal-title":"PLoS One"},{"key":"2020081003473500400_CIT0012","doi-asserted-by":"crossref","first-page":"687","DOI":"10.15585\/mmwr.mm6626a2","article-title":"Babesiosis surveillance \u2013 Wisconsin, 2001\u20132015","volume":"66","author":"Stein","year":"2017","journal-title":"Morb Mortal Wkly Rep"},{"key":"2020081003473500400_CIT0013","doi-asserted-by":"crossref","DOI":"10.1089\/vbz.2012.1198","article-title":"The relevance of forest fragmentation on the incidence of human babesiosis: investigating the landscape epidemiology of an emerging tick-borne disease","volume":"13","author":"Walsh","year":"2013","journal-title":"Vector Borne Zoonotic Dis"},{"key":"2020081003473500400_CIT0014","doi-asserted-by":"crossref","first-page":"14589","DOI":"10.1073\/pnas.1604980113","article-title":"Impact of El Ni\u00f1o Southern Oscillation on infectious disease hospitalization risk in the United States","volume":"113","author":"Fisman","year":"2016","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2020081003473500400_CIT0015","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1126\/science.279.5353.1023","article-title":"Chain reactions linking acorns to gypsy moth outbreaks and Lyme disease risk","volume":"279","author":"Jones","year":"1998","journal-title":"Science"},{"key":"2020081003473500400_CIT0016","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1002\/ecy.2386","article-title":"Tick-borne disease risk in a forest food web","volume":"99","author":"Ostfeld","year":"2018","journal-title":"Ecology"},{"key":"2020081003473500400_CIT0017"},{"key":"2020081003473500400_CIT0018"},{"key":"2020081003473500400_CIT0019","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.mehy.2004.04.006","article-title":"Human babesiosis\u2013an unrecorded reality. Absence of formal registry undermines its detection, diagnosis and treatment, suggesting need for immediate mandatory reporting","volume":"63","author":"Sherr","year":"2004","journal-title":"Med Hypotheses"},{"key":"2020081003473500400_CIT0020"}],"container-title":["Open Forum Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ofid\/article-pdf\/6\/3\/ofz066\/33590335\/ofz066.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ofid\/article-pdf\/6\/3\/ofz066\/33590335\/ofz066.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,10]],"date-time":"2020-08-10T07:50:45Z","timestamp":1597045845000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ofid\/article\/doi\/10.1093\/ofid\/ofz066\/5315596"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,11]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ofid\/ofz066","relation":{},"ISSN":["2328-8957"],"issn-type":[{"type":"electronic","value":"2328-8957"}],"subject":[],"published-other":{"date-parts":[[2019,3]]},"published":{"date-parts":[[2019,2,11]]},"article-number":"ofz066"}}