{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T14:51:48Z","timestamp":1790347908816,"version":"4.1.0"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T00:00:00Z","timestamp":1571961600000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["U38 PS004646"],"award-info":[{"award-number":["U38 PS004646"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21 MH112449"],"award-info":[{"award-number":["R21 MH112449"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 AI138783"],"award-info":[{"award-number":["R01 AI138783"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008374","name":"Center for AIDS Research at Emory University","doi-asserted-by":"crossref","award":["P30 AI050409)."],"award-info":[{"award-number":["P30 AI050409)."]}],"id":[{"id":"10.13039\/100008374","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The incidence of bacterial sexually transmitted infections (STIs) in men who have sex with men (MSM) has increased substantially despite availability of effective antibiotics. The US Centers for Disease Control and Prevention (CDC) recommends annual screening for all sexually active (SA) MSM and more frequent screening for high-risk (HR) MSM. The population-level benefits of improved coverage vs increased frequency of STI screening among SA vs HR MSM are unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We used a network transmission model of gonorrhea (NG) and chlamydia (CT) among MSM to simulate the implementation of STI screening across different scenarios, starting with the CDC guidelines at current coverage levels. Counterfactual model scenarios varied screening coverage and frequency for SA MSM and HR MSM (MSM with multiple recent partners). We estimated infections averted and the number needed to screen to prevent 1 new infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared with current recommendations, increasing the frequency of screening to biannually for all SA MSM and adding some HR screening could avert 72% of NG and 78% of CT infections over 10 years. Biannual screening of 30% of HR MSM at empirical coverage levels for annual SA screening could avert 76% of NG and 84% of CT infections. Other scenarios, including higher coverage among SA MSM and increasing frequency for HR MSM, averted fewer infections but did so at a lower number needed to screen.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The optimal screening scenarios in this model to reduce STI incidence among MSM included more frequent screening for all sexually active MSM and higher coverage of screening for HR men with multiple partners.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ofid\/ofz405","type":"journal-article","created":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T22:42:55Z","timestamp":1572043375000},"source":"Crossref","is-referenced-by-count":21,"title":["Optimizing Coverage vs Frequency for Sexually Transmitted Infection Screening of Men Who Have Sex With Men"],"prefix":"10.1093","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9669-8236","authenticated-orcid":false,"given":"Kevin M","family":"Weiss","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Emory University, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9165-1658","authenticated-orcid":false,"given":"Jeb S","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Emory University, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emeli J","family":"Anderson","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Emory University, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Gift","sequence":"additional","affiliation":[{"name":"Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6695-3141","authenticated-orcid":false,"given":"Harrell","family":"Chesson","sequence":"additional","affiliation":[{"name":"Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle","family":"Bernstein","sequence":"additional","affiliation":[{"name":"Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9918-9493","authenticated-orcid":false,"given":"Kimberly","family":"Workowski","sequence":"additional","affiliation":[{"name":"Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"},{"name":"Department of Medicine, Emory University, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4373-9337","authenticated-orcid":false,"given":"Ashleigh","family":"Tuite","sequence":"additional","affiliation":[{"name":"BlueDot Inc., Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1695-8075","authenticated-orcid":false,"given":"Eli S","family":"Rosenberg","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Emory University, Atlanta, Georgia, USA"},{"name":"Department of Epidemiology and Biostatistics, University at Albany, Albany, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick S","family":"Sullivan","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Emory University, Atlanta, Georgia, USA"},{"name":"Department of Global Health, Emory University, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8840-105X","authenticated-orcid":false,"given":"Samuel M","family":"Jenness","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Emory University, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,10,25]]},"reference":[{"key":"2020081005082671000_CIT0001","volume-title":"Sexually Transmitted Disease Surveillance 2017","author":"Centers for Disease Control and Prevention.","year":"2018"},{"key":"2020081005082671000_CIT0002","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1089\/aid.2015.0013","article-title":"The effect of high rates of bacterial sexually transmitted infections on HIV incidence in a cohort of black and white men who have sex with men in Atlanta, Georgia","volume":"31","author":"Kelley","year":"2015","journal-title":"AIDS Res Hum 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